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Buy Zaxine 550 Mg Tablets Online from a Canadian Pharmacy


Zaxine is a medication that contains rifaximin, which belongs to a class of medications called antibacterial agents. It is used in addition to lactulose to reduce the risk of hepatic encephalopathy recurrence in adults. Hepatic encephalopathy is a condition that frequently develops when a person has chronic liver disease, and the body is unable to get rid of the waste product, ammonia, easily. This FDA-approved medication is available in 550 mg strengths and can be taken orally. So, if you want to buy Zaxine tablets online from a Canadian pharmacy, you must get a valid prescription from your doctor first.

Product Overview

Zaxine, a medication containing rifaximin, falls under the category of antibacterial agents. Its primary use, alongside lactulose, is to minimize hepatic encephalopathy recurrence in adults with chronic liver disease. This condition arises when the body struggles to eliminate ammonia, a waste product. Zaxine, available in 550 mg strength, is an FDA-approved drug taken orally with a valid prescription.

Zaxine serves a dual purpose, also treating Irritable Bowel Syndrome with Diarrhea (IBS-D). The recommended dosage varies for each condition – adults take a 550 mg tablet twice daily for hepatic encephalopathy and one tablet thrice daily for IBS-D.

Administer Zaxine on an empty stomach, swallowing the tablets whole with water and avoiding crushing or chewing. The drug works primarily in the intestines, targeting and slowing down the growth of harmful bacteria, alleviating symptoms of conditions like traveler’s diarrhea and IBS-D.

Despite its benefits, Zaxine has common side effects such as bloating, dizziness, and vomiting, as well as mild effects like itchiness, diarrhea, headache, and nausea. Certain precautions must be taken, especially if you have liver issues or experience antibiotic-related diarrhea.

Zaxine interactions should be noted, including drugs like warfarin, hepatitis C antivirals, and macrolide antibiotics. Alternatives like trimethoprim-sulfamethoxazole or norfloxacin exist, but their usage requires consultation with a healthcare provider.

Uses of Zaxine

Zaxine is used:

  • To minimize the likelihood of adults experiencing a recurrence of hepatic encephalopathy.
  • For the treatment of IBS-D (Irritable Bowel Syndrome with Diarrhea).

How to Use Zaxine?


Zaxine tablets come in only one strength of 550 mg.

Recommended Dosage for Different Patients

Hepatic Encephalopathy: To prevent hepatic encephalopathy, a condition linked to chronic liver disease, adults should take a 550 mg dose twice daily. 

Irritable Bowel Syndrome with Diarrhea (IBS-D): For the treatment of IBS-D, adults are advised to take one tablet (550 mg) three times a day.

[Note: Remember these recommendations may vary depending on person to person. Discuss it with your doctor, and they’ll customize your dosage accordingly.]

How to Take It?

  • Take 550 mg of Zaxine twice a day if you’re an adult.
  • Always take Zaxine on an empty stomach.
  • Swallow the tablets whole with water. 
  • Don’t crush or chew Zaxine tablets.

[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They’ll adjust it as needed over time.]

How Does Zaxine Work?

Zaxine 550 mg doesn’t get into the bloodstream much when you take it by mouth. Instead, it mainly works in the intestines to fight off harmful bacteria. Rifaximin, the active ingredient, targets and slows down the growth of certain bacteria, helping you assist against issues like traveler’s diarrhea and irritable bowel syndrome with diarrhea. 

Important Safety Information

Side Effects

Common side effects of Zaxine include

  • Bloating
  • Dizziness
  • Vomiting
  • Reddish Color to Sweat, Urine, or Tears

Mild side effects of Zaxine include:

  • Itchiness
  • Diarrhea
  • Headache
  • Nausea
  • Reduced Reflexes

[Note: Remember, this list may not cover all possible side effects. Always consult with your healthcare giver for medical advice about side effects.]


Before you start taking any medicine, make sure to tell your doctor about any health issues, allergies, or other medications you’re using.

Antibiotic-Related Diarrhea: Like some other antibiotics, rifaximin may cause severe diarrhea linked to a condition called pseudomembranous colitis. If you get severe diarrhea while taking this medicine or within a few weeks of using it, contact your doctor.

Liver Issues: If you have liver problems, this medicine might build up in your body and cause side effects. Discuss with your doctor how it might affect you, how your liver condition can influence the dosage and effectiveness, and whether special monitoring is necessary. Your doctor may want to check your liver function regularly with blood tests while you’re on this medicine.


Let your doctor know if you’re pregnant, breastfeeding, or anything important about your health. These things can impact how you should use the medicine.

Pregnancy: Avoid using this medicine during pregnancy unless the benefits are greater than the risks. If you become pregnant while using it, contact your doctor right away.

Breastfeeding: It’s unclear if rifaximin passes into breast milk. If you’re breastfeeding and taking this medicine, talk to your doctor about whether you should continue.

Children: The safety and effectiveness of this medicine for children have not been proven.

Missed Dose

If you forget to take a dose, take it as soon as you remember and stick to your usual schedule. If it’s nearly time for your next dose, just skip the missed one and stick to your regular routine. Don’t take two doses to make up for the one you missed. If you’re unsure about what to do, ask your doctor or pharmacist for guidance.

[Note: If you have missed a dose of your medication and are unsure about when to take the next one, immediately consult your doctor or pharmacist.]


If you think you’ve taken Zaxine (rifaximin) more than the recommended dose, it’s really important to get help from a doctor right away. Taking too much of this medicine can be very serious. Additionally, make sure to mention any symptoms or discomfort you’re experiencing, as this information will help the medical professionals assist you better.

[Note: If you consumed more than the recommended dose, get medical help right away or call the Poison Help line at 1-800-222-1222.]


  • Keep this medicine at room temperature. 
  • Shield it from light and moisture. 
  • Make sure it’s not accessible to children while storing.

[Note: Discuss with your healthcare professional about the proper disposal of any unused medicine and any questions you may have regarding its storage.]

Zaxine Interactions

Zaxine (rifaximin) might have interactions with the following:

  • Quinidine
  • Warfarin
  • BCG vaccine
  • Quinine
  • Eliglustat
  • Hepatitis C Antivirals
  • Macrolide Antibiotics
  • Dronedarone
  • Flibanserin
  • Lapatinib
  • Cyclosporine
  • Verapamil
  • Elagolix
  • Lumacaftor and Ivacaftor
  • Amiodarone
  • Erdafitinib
  • Carvedilol
  • Azole” Antifungal Medications
  • Propafenone
  • Ritonavir
  • Osimertinib
  • Sodium Picosulfate

[Note: This isn’t a complete list, and there could be other drugs that interact with (drug name). Make sure to tell your doctor about any prescription, over-the-counter medicines, and herbal products you’re taking.]

Zaxine Alternatives

  • Septra (trimethoprim-sulfamethoxazole)
  • Noroxin (norfloxacin)
  • Flagyl (metronidazole)
  • Actisite (tetracycline)
  • Augmentin (amoxicillin-clavulanic acid)
  • Sibofix (rifaximin)

[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.] 

Frequently Asked Questions

Should Zaxine be taken with food?

No, you should not take this medicine with food. Follow your doctor’s instructions precisely when taking this medicine. 

How is rifaximin excreted?

The majority of the antibacterial activity in the bile is attributed to this metabolite. However, Rifampicin is excreted almost equally in both bile and urine, with the recovery in these two fluids being of similar magnitude.

What is the half-life of rifaximin?

The average half-life of rifaximin in individuals without health conditions was found to be 5.6 hours, while in patients with irritable bowel syndrome with diarrhea (IBS-D), it extended to 6 hours. This indicates that the elimination rate of rifaximin varies between healthy subjects and those with IBS-D.

Is rifaximin safe for kidneys?

Although rifaximin has shown protective effects against acute kidney injury (AKI) and hepatorenal syndrome (HRS) in cirrhosis induced by alcohol, its impact on the long-term renal function of cirrhotic patients with other etiologies remains unclear.

Is it possible to take Zaxine with other antibiotics? 

A healthcare provider should be consulted before taking Zaxine with other antibiotics. Treatment outcomes may be affected if antibiotics are combined and have additive effects. To ensure safe and effective treatment, inform your healthcare provider about all medications you’re taking. If you mix antibiotics without professional advice, their effectiveness can be affected, and side effects may occur.

Our Guarantee

At, we assure you the most affordable price to buy Zaxine from Canada. Rest easy knowing that your order will be dispatched from a reputable Licensed Canada Pharmacy Online, adhering to the highest standards of quality and authenticity. Our discounted medications are shipped directly from Canada to your doorstep, ensuring a swift and secure delivery experience. To conveniently access Zaxine tablets at a substantial cost, call us at 1-888-779-2193 toll-free.


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