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Ziac

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Product Details

Description

Buy Ziac Online from Licensed Canadian Pharmacies

Ziac, a combination tablet containing bisoprolol fumarate and hydrochlorothiazide, is a reliable solution for lowering high blood pressure (hypertension). By leveraging the unique mechanisms of its two active agents, Ziac effectively reduces your heart’s workload and fluid volume, making it easier for your body to maintain healthy blood pressure.

Since it includes a diuretic and a beta-blocker, it must be used under medical supervision with periodic monitoring of heart, kidney, and electrolyte status. You’ll want to stay aware of symptoms like dizziness, fatigue, or swelling. Proper use helps maximize blood pressure control while minimizing risks. If you are ready to buy Ziac online from Canada, get a prescription from your doctor.

Generic NameBisoprolol fumarate/Hydrochlorothiazide
Brand NameZiac
FormsOral Tablets
Strengths Available2.5 mg/6.25 mg & 5 mg/6.25 mg
Packaging30 tablets per bottle (or equivalent prescription packaging)
Requires PrescriptionPrescription only (Rx)
Ships to the USAYes
Uses and Benefits

What Are the Uses of Ziac?

  • Ziac is prescribed to lower hypertension

Benefits of Ziac

  • Combines a beta-blocker and a diuretic to tackle hypertension via two different pathways.
  • Helps lower blood pressure, reducing the risk of stroke, heart attack, and kidney damage.
  • May reduce the dose of either agent needed when used alone, potentially lowering side effect risks.
  • The diuretic component helps remove extra fluid and salt, easing strain on the cardiovascular system.
  • The beta-blocker component slows heart rate and decreases cardiac workload.
  • Once-daily dosing helps improve adherence and consistency in blood pressure control.
  • Because the component doses (for example, 6.25 mg HCTZ) are low, the risk of electrolyte disturbance may be less pronounced than with higher diuretic doses.
  • In controlled use, Ziac can provide balanced control of blood pressure with a manageable safety profile.
Dosage

What Are the Recommended Ziac Dosages?

Ziac Dosage for High Blood Pressure (Hypertension)

  • Starting dose: 2.5 mg/6.25 mg once daily, usually in the morning.
  • Titration: Increase at 14 day intervals, depending on response, up to 10 mg/6.25 mg or as per clinician judgment.
  • Maximum: Some labels permit up to 20 mg bisoprolol/12.5 mg HCTZ in total (that is, two 10/6.25 tablets) once daily.
  • Renal/hepatic impairment: Dosing should be adjusted cautiously; close monitoring is required.
  • Geriatrics: No routine adjustment for age alone, though comorbidities (kidney/liver) may influence dosing.
  • Pediatric: Not established. It is not commonly used in children.
Usage Guide

What Are the Usage Guidelines for Ziac?

Here’s how to use Ziac properly:

  • Take Ziac by mouth once daily, with or without food.
  • Try to take it at the same time each day to keep levels stable.
  • Avoid taking it late in the evening to prevent overnight urination (due to the diuretic effect).
  • Do not abruptly stop taking Ziac. Doses should be tapered under medical supervision.
  • Maintain adequate hydration, but avoid excessive fluid intake without guidance.
  • Monitor blood pressure, kidney function, and electrolytes regularly as directed.
  • Inform your doctor if you experience symptoms like lightheadedness, swelling, or irregular heartbeats.
  • Stay consistent with lifestyle measures (diet, exercise) to support its effect.
How It Works

How the Ziac Works?

Ziac combines bisoprolol, a selective beta-1 blocker, and hydrochlorothiazide, a thiazide diuretic. Bisoprolol works by slowing the heart rate and reducing the force of contraction, thereby lowering cardiac workload and blood pressure. Hydrochlorothiazide increases urine output by blocking salt reabsorption in the kidneys, reducing blood volume and vascular strain. Together, they act synergistically to lower blood pressure more effectively than either would alone, while potentially balancing out adverse effects like electrolyte loss.

Side Effects

What Are the Side Effects of Ziac?

Common Ziac side effects may include:

  • Dizziness or lightheadedness, especially on standing
  • Fatigue, weakness, or tiredness
  • Headache
  • Diarrhea, nausea, or stomach upset
  • Cough
  • Bradycardia or slow heart rate (from the beta-blocker effect)
  • Changes in electrolyte levels (for example, low potassium)

Serious side effects (rare):

  • Worsening heart failure or fluid retention
  • Heart block or conduction abnormalities
  • Bronchospasm in susceptible individuals (for example, with asthma)
  • Severe hypotension or syncope
  • Skin reactions or photosensitivity

Note: Contact your healthcare provider immediately if you experience any severe symptoms or unusual changes.

Warnings

What Are the Warnings for Ziac?

If your doctor has prescribed you Ziac tablets, consider the following warnings associated with this medication:

  • Avoid use if you have severe bradycardia, second- or third-degree heart block, cardiogenic shock, or overt heart failure without stabilization.
  • Use cautiously in patients with respiratory diseases (for example, asthma) due to the risk of bronchospasm from beta-blockade.
  • May worsen peripheral artery disease or mask signs of hypoglycemia in diabetics.
  • The diuretic component can cause dehydration, electrolyte imbalance, or kidney dysfunction. Monitor kidney, sodium, and potassium levels.
  • Use caution in the elderly or those with impaired renal/hepatic function.
  • May increase the risk of skin cancer. Limit sun exposure, use sunscreen, and monitor skin changes.
  • Don’t stop abruptly. Dosing should be tapered to avoid rebound hypertension or worsening cardiac conditions.
Safety Guide

What Are the Safety Guidelines for Ziac?

To use Ziac safely and effectively:

  • Keep consistent with dosing time to maintain stable blood levels.
  • Regularly monitor blood pressure, electrolytes, heart rate, and kidney function.
  • Stay hydrated but avoid overhydration, especially in hot weather or when taking diuretics.
  • Avoid abrupt discontinuation. Always taper under medical supervision.
  • Wear sunscreen, protective clothing, and avoid extended sun exposure.
  • Inform other health providers and your pharmacist that you are using Ziac.
  • Be cautious with activities requiring alertness if dizziness or fatigue occurs.
  • Use with care when combining with other medications that affect heart rate or kidney function.
Missed Dose

If you miss a dose of Ziac, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue your regular dosing schedule. Do not take two doses at once to make up for a missed dose.

Overdose

If someone takes too much Ziac, symptoms may include severe low blood pressure, very slow heart rate, dizziness, or fainting. Seek emergency medical care immediately or contact poison control at 1-800-222-1222. Bring the medication packaging so professionals know exactly what was taken.

Storage Guide

What Are the Storage Guidelines for Ziac?

To maintain potency and safety:

  • Store Ziac tablets at room temperature (68 to 77 °F / 20 to 25 °C).
  • Short excursions between 59–86 °F (15 to 30 °C) are acceptable.
  • Keep tablets in a tightly closed container, away from moisture and heat.
  • Protect from direct light.
  • Avoid storing in the bathroom or near steam.
  • Keep out of reach of children and pets.
  • Discard unused medication after its expiration date.
  • Do not transfer tablets to unlabeled containers.
Interactions

Ziac may interact with several medications. Some notable ones include:

  • Digoxin
  • Calcium channel blockers (for example, Verapamil, Diltiazem)
  • NSAIDs (Nonsteroidal anti-inflammatory drugs)
  • Other beta-blockers or antihypertensives
  • Corticosteroids
  • Diuretics
  • Antidiabetic agents
  • Lithobid (lithium)
Alternatives

What Are the Alternatives for Ziac?

If Ziac is not suitable for you, your healthcare provider might consider:

  • Tenoretic (atenolol/chlorthalidone)
  • Lotrel (amlodipine/benazepril)
  • Diovan HCT (valsartan/hydrochlorothiazide)
  • Zestoretic (lisinopril/hydrochlorothiazide)
  • Elisor (losartan/hydrochlorothiazide)
Cost & Coupons

Why Buy Ziac from Polar Bear Meds?

At Polar Bear Meds, we’re committed to making prescription medications like Ziac more accessible and affordable for USA patients. Our prices are significantly lower than typical USA pharmacy retail rates without compromising on safety or quality. Every order is sourced exclusively from licensed and trusted pharmacies and undergoes complete prescription verification to ensure compliance and authenticity. We offer discreet, trackable shipping to all USA states, along with refill support for ongoing treatment. Our friendly customer service team is here to help you.

Cost & Coupons

Get Ziac delivered straight from Canada to your doorstep in the USA. You can also save more by using the coupon code “WELCOMEPB10” for 10% off on your first order. There are no hidden handling or processing fees, as we believe in complete transparency. Looking to save even more? Join our referral program and earn a $20 credit every time you refer a friend or a family member. Your referral will also receive a $20 credit, so everyone wins. Additionally, after every 10 verified customers' referrals, you'll receive a $100 credit in your account as a thank-you for spreading the word.

FAQ

Guarantee

AtPolar Bear Meds, your safety is our priority. Every order is dispensed from a fully licensed Canadian pharmacy following strict standards for quality, security, and patient care. To conveniently buy Ziac from Canada at a substantial cost, call us at 1-888-779-2193 toll-free.

Important Notice

The content provided on the Polar Bear Meds website serves to increase knowledge about healthcare products and medical conditions and is strictly for informational purposes. It should not replace professional medical advice. We urge you to consult with a qualified healthcare professional prior to utilizing any prescription or over-the-counter medication. Our platform grants access to an extensive array of products, sourced internationally, including Canada. We collaborates with a licensed pharmacy partner in Canada and trusted dispensing pharmacies globally. All affiliated fulfillment centers are accredited by the regulatory authorities of their respective countries.

Dr. Jackson Miller

Medically Reviewed by "Dr. Jackson Miller (M.D)"

Dr. Jackson Miller is a board-certified medicine physician & hospitalist. He is a healthcare professional with a strong background in patient care. With years of experience and a patient-first approach, he believes the foundation of good health is a patient who feels informed and empowered. He contributes to medical content review, drawing on his background in clinical practice and patient education. He focuses on presenting health information in a clear, accurate, and accessible way to help readers make informed decisions. His work emphasizes clarity, evidence-based guidance, and understandable explanations of medical topics.

Find Dr. Jackson Miller on:LinkedIn
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We offer competitive pricing on all our medications. We'll match if you find a lower price on an identical product at a verified Canadian online pharmacy!

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