Is Januvia used for weight loss?

No. Januvia (sitagliptin) is not approved for weight loss. It is generally weight-neutral and is used to help control blood sugar (glucose) in adults with type 2 diabetes along with diet & exercise.

How quickly does Januvia start working?

Januvia (sitagliptin) begins to lower blood glucose levels within hours, with noticeable effects over 1-2 weeks after initiation of treatment. However, it may take up to three to six months (or 24 weeks) to see its full therapeutic effect on average blood sugar (A1C) levels.

Is Januvia legal to buy online from Canada?

Yes, Januvia can be ordered online from Canada for personal use when a valid prescription is provided, and the medication is dispensed by a licensed pharmacy like Polar Bear Meds.

Is Januvia safe for the kidneys?

Januvia is generally safe for the kidneys when used as prescribed. However, it requires careful dose adjustment in patients with existing kidney impairment. Your physician will assess your renal function before and during treatment to ensure safe dosing.

How long can I take Januvia for type 2 diabetes?

Januvia (sitagliptin) is intended for long-term use and can be taken indefinitely, potentially for life, as part of your diabetes management plan. Many patients take it for years under medical supervision because type 2 diabetes is a chronic (ongoing) condition that requires continuous management, not a cure.

Why is Januvia cheaper in Canada?

Januvia is often cheaper in Canada because prescription drug prices are regulated by the Canadian government, which helps keep medication costs lower compared to U.S. pricing.

Does Januvia cause hair loss?

Hair loss was not reported as a Januvia side effect. If hair thinning occurs, it may be related to other medical conditions or medications rather than Januvia itself.

Is a U.S. prescription required to buy Januvia?

Yes, a valid prescription from a licensed healthcare provider is required to buy Januvia, including when ordering from a licensed Canadian pharmacy.

Buy Januvia (Sitagliptin) Online for Type 2 Diabetes

Name: Januvia
Brand: Januvia
Availability: InStock
Rating: 4.9 (371 reviews)

What Is Januvia Used For?

Januvia (sitagliptin) is a prescription tablet indicated as an adjunct to diet & exercise to improve glycemic control in adults with type 2 diabetes mellitus. It is part of a class of drugs called DPP‑4 inhibitors and works alongside a healthy diet and regular exercise to improve how your body manages blood glucose (sugar). Common adverse reactions of Januvia include upper respiratory tract infection, nasopharyngitis, and headache.

Januvia is not used for type 1 diabetes or diabetic ketoacidosis, and it must be prescribed by a healthcare provider. It helps reduce post-meal blood sugar increases and supports steady glucose control throughout the day. For added convenience, Januvia can be ordered from licensed Canadian pharmacies that ship to the U.S.

Quick Facts About Januvia

Category	Details
Brand name	Januvia
Generic name	Sitagliptin
Drug class	DPP‑4 inhibitor (dipeptidyl peptidase‑4 inhibitor)
FDA approval	Yes (FDA-approved in 2006)
Indication	Improves blood sugar control in adults with type 2 diabetes mellitus (used with diet and exercise)
Limitations	Not for type 1 diabetes or diabetic ketoacidosis (DKA)
Administration	Oral tablet, taken once daily
Strengths available	25 mg, 50 mg, 100 mg
Prescription required	Yes
Storage	Room temperature, away from moisture and light
Pregnancy Warning	Safety & effectiveness in pregnancy have not been established; use only if clearly needed under medical supervision
Combination therapy	May be prescribed with metformin, sulfonylureas, or insulin
Manufacturer	Merck & Co., Inc.

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Januvia Dosage Guide

Patient Group	Recommended Dose	Notes
Adults with normal kidney function (eGFR ≥ 45 mL/min/1.73 m²)	100 mg once daily	Can be taken with or without food
Moderate renal impairment (eGFR 30–44 mL/min/1.73 m²)	50 mg once daily	Assess renal function before and during treatment
Severe renal impairment, end‑stage renal disease (ESRD) requiring dialysis, or (eGFR < 30 mL/min/1.73 m²)	25 mg once daily	May be taken without regard to dialysis timing
Children	Not FDA‑approved	Safety and efficacy not established

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How to Take Januvia Tablets

Take Januvia (sitagliptin) exactly as instructed by your healthcare provider.
You may take it with or without food, but try to take it around the same time every day.
Keep taking this medicine even if you feel well; high blood sugar often has no symptoms.

Januvia Mechanism of Action

Januvia contains sitagliptin, which blocks the enzyme DPP-4 (dipeptidyl peptidase-4). This enzyme normally degrades incretin hormones such as GIP and GLP-1, which help regulate blood glucose. By preventing their breakdown, Januvia increases insulin release and reduces glucagon (a hormone that raises blood glucose levels). This helps lower your blood glucose levels in patients with type 2 diabetes.

Januvia Side Effects

Common	Serious	Rare
Headache	Pancreatitis (severe stomach pain, nausea, vomiting)	Stevens‑Johnson syndrome (severe skin reaction)
Stuffy/runny nose	Severe joint pain
Sore throat	Kidney problems	Severe allergic reactions (anaphylaxis, angioedema)
Cough	Allergic reactions (rash, swelling of face/lips/tongue, difficulty breathing)	Skin blistering or peeling
Diarrhea	Low blood sugar (especially with insulin or sulfonylureas)

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When to Call Your Doctor While Taking Januvia Tablets

Stop and call your doctor right away if you experience severe stomach pain, difficulty breathing, signs of pancreatitis, swelling of the face or throat, or any serious skin reaction

Januvia Vs. Other Type 2 Diabetes Medicines

Here’s a simple comparison of Januvia with other common type 2 diabetes medicines, highlighting the key differences:

Comparison	Key Difference
Januvia vs Jardiance	Januvia lowers blood sugar without weight change. Jardiance may help with weight loss and has proven heart & kidney benefits.
Januvia vs Invokana	Januvia has a low risk of hypoglycemia. Invokana also lowers sugar, but may cause more urination and dehydration.
Januvia vs Janumet	Janumet combines Januvia with metformin for stronger glucose control than Januvia alone.
Januvia vs Jardiance (Cost)	Both are usually similar in price, but the actual cost depends on the pharmacy, insurance, and discount programs.
Januvia vs Ozempic	Januvia is an oral tablet. Ozempic is an injection that usually gives more weight loss and stronger A1C reduction.
Januvia vs Metformin	Metformin is first-line, low-cost. Januvia is used if metformin isn’t tolerated or as add-on therapy.
Januvia vs Glipizide	Januvia has a lower risk of hypoglycemia. Glipizide may cause low blood sugar and weight gain.

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Important Safety Information About Januvia Tablets

Do not use Januvia if you are allergic to sitagliptin or any ingredient in the medication.
Before starting Januvia, tell your doctor if you:
Do not share your tablets with another person.
When used with insulin secretagogues or insulin, the risk of hypoglycemia increases; monitor blood glucose closely.
Consider discussing the risks and benefits with your doctor if you have existing heart failure risk factors.
If you miss a Januvia dose, take it as soon as you remember. If it is almost time for your next one, skip the missed dose. Do not double up.
An overdose of Januvia may cause nausea or abdominal pain. Seek medical attention or call Poison Control if a Januvia overdose is suspected.

Januvia Clinical Trials

Januvia (sitagliptin) has been studied in multiple randomized, controlled clinical trials involving adults with type 2 diabetes. These studies showed that Januvia significantly lowers A1C levels when used alone or as add-on therapy with medications such as metformin, sulfonylureas, or insulin.

In the trial evaluating cardiovascular outcomes with sitagliptin (TECOS), sitagliptin was shown to have a neutral effect on major cardiovascular outcomes. It did not increase the risk of nonfatal myocardial infarction, cardiovascular death, nonfatal stroke, or hospitalization for heart failure compared with placebo. Overall, studies indicate that Januvia is generally considered well-tolerated, with a low risk of hypoglycemia when not combined with insulin or sulfonylureas.

What Medications Can Interact with Januvia?

Januvia tablets can interact with several medications. Some of the main Januvia interactions are listed below:

Januvia Interaction with Other Diabetes Medications
Januvia Interactions with Heart Medications
Januvia Interactions with Seizure Medications

Januvia Alternatives

Zituvio (sitagliptin)
Janumet (sitagliptin / metformin)
Onglyza (saxagliptin)
Tradjenta (linagliptin)
Nesina (alogliptin)

Why Buy Januvia from Polar Bear Meds?

When you choose Polar Bear Meds to buy Januvia (sitagliptin) online, you get trusted, affordable access to your prescription medication.

Offers lower prices, often up to 90% lower than U.S. retail pharmacies, for many medications.
All medications are dispensed by licensed Canadian pharmacies.
Ships directly to the U.S.
Secure ordering and dedicated customer support.
Extra 10% off for first-time customers with the Januvia coupon WELCOMEPB10.

How Can You Buy Januvia (Sitagliptin)?

Here are the general steps on how to order Januvia online from Polar Bear Meds:

Select Januvia on the Polar Bear Meds website.
Complete checkout with U.S. shipping details.
Upload or send your valid prescription.
Our pharmacist will verify your order.
Once approved, your Januvia tablets will be shipped to your home.

Januvia Frequently Asked Questions

Shipping Januvia from Canada to the U.S.

Order Januvia confidently with reliable U.S. delivery from our trusted Canadian pharmacy partners. Most orders arrive within 3-5 business days via Xpress Post once your prescription is approved. You can track your order online in real time, and our support team is ready to assist until your medication reaches your doorstep.

Important Notice

This information is for educational purposes only and does not replace any professional medical advice, diagnosis, or treatment. Always consult a licensed healthcare expert before starting, stopping, or changing Januvia dosages. Individual results, dosing, and Januvia side effects may vary.