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Jardiance

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Product Details

What Is Jardiance?

What Is Jardiance?

Jardiance is a prescription medication that contains the active ingredient empagliflozin and belongs to a class of drugs called SGLT2 inhibitors. It is primarily used to treat T2D (type 2 diabetes) by decreasing blood sugar levels. Jardiance also reduces the risk of heart-related death in adults with T2D and heart disease. It helps prevent hospitalization for heart failure and slows the progression of chronic kidney disease.

Quick Facts About Jardiance

Quick Facts About Jardiance

Product NameJardiance
Active IngredientEmpagliflozin
Drug TypeSGLT2 (Sodium-Glucose Co-Transporter 2) Inhibitors
FDA Approval Status & DateFDA-approved for Type 2 diabetes, expanded indications for CV risk reduction, heart failure, and chronic kidney disease
Available FormsOral tablets
Strengths Available10 mg, 25 mg
Routes of AdministrationBy mouth (tablets)
Administration FrequencyOnce daily
Jardiance UsesLowers blood sugar in type 2 diabetes.

Reduces the risk of heart-related death in people with type 2 diabetes and heart disease.

Helps prevent hospitalization for heart failure (with or without diabetes).

Slows down chronic kidney disease progression and lowers the risk of kidney/heart complications.
Elimination Half-Life12.4 hours
Jardiance StorageStore at room temperature (20°C-25°C)
PregnancyNot recommended (risk to fetus, esp. in 2nd/3rd trimester)
Legal StatusRx only
ManufacturerBoehringer Ingelheim (co-marketed with Eli Lilly)

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What Are the Uses of Jardiance?

What Are the Uses of Jardiance?

Jardiance is FDA-approved to:

  • Treat type 2 diabetes (T2D) in adults and children aged 10 years and older
  • Lower the chances of cardiovascular death in adults with type 2 diabetes & established heart disease.
  • Reduce the risk of cardiovascular death & hospitalization in adults with heart failure, whether or not they have diabetes.
  • Slow the progression of CKD (chronic kidney disease) and reduce the risk of cardiovascular (CV) death in adults with CKD.
How Does Jardiance (empagliflozin) Work?

How Does Jardiance (empagliflozin) Work?

Jardiance (empagliflozin) works by helping your kidneys get rid of extra sugar from your blood. Normally, the kidneys filter sugar and send it back into the bloodstream, but Jardiance blocks a protein called SGLT2 that does this job. As a result, more sugar leaves the body through urine, which lowers blood sugar levels. This is why Jardiance helps protect both the heart and kidneys, not just control blood sugar.

Jardiance Dosage Guide

Jardiance Dosage Guide

Follow this Jardiance dosing schedule to effectively manage or treat your condition:

Population / IndicationYour doctor may increase to 25 mg once daily if tolerated.Notes
Jardiance for Type 2 Diabetes (Adults)Start with 10 mg once dailyYour doctor may increase the Jardiance dose to 25 mg once daily if tolerated, and better control is needed.
Jardiance for Heart Failure (Adults)10 mg once dailyThis may reduce the risk of CV death and hospitalization.
Jardiance for Chronic Kidney Disease (Adults)10 mg once dailyJardiance slows kidney disease progression and reduces CV risk.
Jardiance for Type 2 Diabetes + CV Disease (Adults)10 mg once dailyThis may reduce the risk of cardiovascular death.
Children ≥10 years (Type 2 Diabetes)10 mg once dailyYour doctor may increase to 25 mg once daily if tolerated.

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How and When to Take empagliflozin (Jardiance) Tablets?

How and When to Take empagliflozin (Jardiance) Tablets?

You must follow these Jardiance administration guidelines for effective use:

  • Take one tablet of Jardiance once daily. Morning is the best time to take it.
  • This tablet can be taken with or without food
  • Swallow the whole Jardiance tablet with water. Do not crush or chew.
  • Take this medication at the same time every day.
  • Stay hydrated while taking Jardiance tablets.
What Are the Jardiance Warnings?

What Are the Jardiance Warnings?

Before starting Jardiance, it’s important to understand these safety warnings:

  • Jardiance tablets may cause diabetic ketoacidosis (DKA). This is a very serious condition where too much acid builds up in the blood. Symptoms of DKA may include stomach pain, nausea, vomiting, confusion, and difficulty breathing.
  • It can increase the risk of genital mycotic infections in both men and women.
  • Rarely, Jardiance has been linked to Fournier’s gangrene. This is a life-threatening infection in the genital or rectal area. Immediate medical attention is needed if redness, pain, swelling, or tenderness occurs.
  • Dehydration and low blood pressure may happen because Jardiance increases urination. This can lead to dizziness, especially in older adults, people with kidney problems, or those taking diuretics. Acute kidney injury can occur if dehydration reduces blood flow to the kidneys.
  • The risk of hypoglycemia is higher when Jardiance is taken with insulin or sulfonylurea medicines.
  • Jardiance may cause lower limb problems, including amputation risk, which have been reported with SGLT2 inhibitors. Patients should check their feet regularly for ulcers, infections, or wounds.
What Are the Precautions for empagliflozin (Jardiance)?

What Are the Precautions for empagliflozin (Jardiance)?

Patients taking Jardiance should follow certain precautions to ensure safe use of the medication:

  • This medication is not recommended for people with severe kidney impairment or for those on dialysis.
  • Jardiance may increase LDL cholesterol, so cholesterol levels should be monitored during treatment.
  • Patients should drink plenty of fluids to stay hydrated and reduce the risk of dehydration.
  • Jardiance is not advised during pregnancy or breastfeeding, as it may harm the newborn or fetus.
  • Alcohol intake should be limited because it increases the risk of ketoacidosis.
  • Jardiance should be stopped temporarily before major surgery to lower the risk of ketoacidosis.
  • Jardiance is not FDA-approved for type 1 diabetes and weight loss.
What to Do If You Forget to Take Your Jardiance Dose?

What to Do If You Forget to Take Your Jardiance Dose?

If you forget to take your Jardiance dose, take it as soon as you remember. However, if it is almost time for your next scheduled Jardiance dose, skip the missed one. After that, you can continue with your regular Jardiance dosing schedule. Do not take two doses of Jardiance at once to make up for the missed dose, as this may increase the risk of serious side effects.

What Happens If You Take Too Much Jardiance?

What Happens If You Take Too Much Jardiance?

If you take more Jardiance than prescribed, contact your doctor immediately. Taking more than the prescribed amount can lead to dehydration, low blood pressure, or dangerously low blood sugar levels (hypoglycemia), especially if taken with other diabetes medicines. If you suspect a Jardiance overdose, contact the poison control center or your healthcare provider immediately.

What Are the Jardiance Side Effects?

What Are the Jardiance Side Effects?

Common Jardiance Side EffectsRare or Serious Side Effects of Jardiance
Increased urinationDiabetic ketoacidosis (DKA)
Thirst or dehydrationGenital yeast infections
Urinary tract infections (UTIs)Fournier’s gangrene
Joint painAcute kidney injury
Weight lossHypoglycemia
Increased cholesterolLower limb amputation
NauseaSevere dehydration and low blood pressure (hypotension)

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Jardiance Vs. Other Medications for Type 2 Diabetes

Jardiance Vs. Other Medications for Type 2 Diabetes

FeatureJardiance (empagliflozin)MetforminSulfonylureasSemaglutide
FormOral tabletOral tabletOral tabletInjection (weekly)
Best forPatients needing blood sugar control plus heart/kidney protectionFirst-line therapy for most patientsQuick blood sugar loweringPatients needing weight loss and heart protection
EffectiveStrong for lowering blood sugar and reducing complicationsVery effective for glucose controlEffective but risk of hypoglycemiaVery effective for glucose control and weight loss
Major BenefitsProtects the heart and kidneysAffordable, widely availableRapid glucose reductionWeight loss and cardiovascular benefit
Major RisksUTIs, dehydration, ketoacidosisGastrointestinal upsetHypoglycemia, weight gainNausea, vomiting, injection required

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Jardiance Vs. Other Medications for CKD

Jardiance Vs. Other Medications for CKD

FeatureJardiance (empagliflozin)Kerendia (finerenone)Farxiga (dapagliflozin)ACE inhibitors or ARBs
FormOral tabletOral tabletOral tabletOral tablet
Best forAdults with CKD (with or without diabetes), especially those at risk of heart failureCKD with type 2 diabetes and high risk of progressionCKD patients with or without diabetes, especially those with heart failureCKD patients with hypertension or proteinuria
EffectiveProven to slow CKD progression and reduce cardiovascular deathEffective in reducing kidney inflammation and fibrosisEffective in slowing CKD progression and lowering hospitalization riskEffective in reducing proteinuria and protecting kidney function
Major BenefitsProtects the kidneys and heart, reduces hospitalizationSlows CKD progression, lowers cardiovascular riskKidney and heart protection reduces hospitalizationBlood pressure control, kidney protection
Major RisksUTIs, genital infections, dehydration, ketoacidosisHigh potassium (hyperkalemia), dizzinessUTIs, dehydration, ketoacidosisCough (ACE inhibitors), high potassium, low blood pressure

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How Should Jardiance Be Stored?

How Should Jardiance Be Stored?

Consider the following Jardiance storage guidelines to keep the medication safe:

  • Jardiance tablets are best kept at room temperature, between 20°C-25°C (68°F-77°F).
  • These tablets should be kept away from moisture and direct light.
  • Do not store Jardiance tablets in the bathroom or near the kitchen sink.
  • Always keep Jardiance tablets in their original container with the lid tightly closed.
  • Ensure it is out of reach of children and pets.
  • Do not use the Jardiance tablets after the expiration date, and avoid freezing them.
  • If you have unused or expired Jardiance tablets, dispose of them safely according to local pharmacy or medical guidelines rather than throwing them in household trash.
Jardiance Interactions

Jardiance Interactions

  • Sulfonylureas (e.g., glipizide, glyburide)
  • Glinides (e.g., repaglinide, nateglinide)
  • Losartan
  • Lisinopril
  • Amlodipine
  • Aspirin
  • Atorvastatin
  • Carvedilol
  • Clopidogrel
  • Apixaban (Eliquis)
  • Sacubitril/valsartan (Entresto)
  • Famotidine
  • Gabapentin
  • Levothyroxine
  • Metformin
Jardiance Alternatives

Jardiance Alternatives

  • Farxiga (dapagliflozin)
  • Ozempic (semaglutide)
  • Mounjaro (tirzepatide)
  • Januvia (sitagliptin)
  • Metformin
  • Afrezza (inhaled insulin)
  • Brenzavvy
  • Kerendia (finerenone)
Why Buy Jardiance Online from Polar Bear Meds?

Why Buy Jardiance Online from Polar Bear Meds?

A high Jardiance cost can make managing type 2 diabetes difficult for many patients. That is why people choose Polar Bear Meds to buy Jardiance online from Canada at affordable prices. By ordering from licensed Canadian pharmacies, customers can save up to 80% on Jardiance prescription prices compared to U.S. pharmacies.

This helps make type 2 diabetes treatment more affordable while ensuring safe access. We also offer extra savings for new customers with our Jardiance coupon code “WELCOMEPB10,” which gives 10% off your first order. Jardiance orders ship quickly and generally arrive within 3-5 business days via Xpress Post.

Important Disclaimer

Important Disclaimer

This information is for general knowledge only and does not replace medical advice. Always talk to your pharmacist or doctor before starting, stopping, or changing any medicine, including Jardiance. Each person’s health condition is different, and only a healthcare professional can decide the right treatment. Do not use this information to diagnose or treat any medical problem. In case of an emergency, seek medical help immediately. The authors are not responsible for any harm caused by using this information.

Jardiance FAQs

Jardiance FAQs

Dr. Jackson Miller

Medically Reviewed by Dr. Jackson Miller (M.D)

Dr. Jackson Miller is a board-certified medicine physician & hospitalist. He is a healthcare professional with a strong background in patient care. With years of experience and a patient-first approach, he believes the foundation of good health is a patient who feels informed and empowered. He contributes to medical content review, drawing on his background in clinical practice and patient education. He focuses on presenting health information in a clear, accurate, and accessible way to help readers make informed decisions. His work emphasizes clarity, evidence-based guidance, and understandable explanations of medical topics.

Find Dr. Jackson Miller on:LinkedIn

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