Felodipine

Plendil

Plendil, or felodipine, is a prescription medication used to treat hypertension (high blood pressure). It is a calcium channel blocker that relaxes the heart and blood vessels, allowing for more effortless blood flow. The typical starting dosage is 2.5 to 5 mg once daily, with a maximum recommended dosage of 20 mg daily. Plendil should be taken consistently and swallowed whole. Patients with liver disease, low blood pressure, or heart failure should use this medication with caution. Lastly, if you are planning to buy Plendil online, do not forget to inform your healthcare provider about the medications you take to avoid potential drug interactions.

 Product Overview

Plendil, also known as felodipine, is a prescription medication used primarily in managing hypertension (high blood pressure). This FDA-approved medication works by relaxing the muscles of the heart and blood vessels, enabling smooth blood flow and reducing the pressure on the heart. It is available in extended-release tablets with strengths of 2.5 mg, 5 mg, and 10 mg. Adults typically start with a dose of 2.5 to 5 mg once daily, which may be adjusted based on response and tolerance. The maximum recommended dosage is 20 mg per day. 

Plendil should be taken consistently, with or without food, and the tablets should be swallowed whole without crushing or breaking. It is generally well-tolerated, but common side effects can include swelling of the hands, ankles, or feet (edema), headache, flushing, dizziness, and increased heart rate. More severe side effects, such as overgrowth of gums, rash, and fainting, may occur and should be reported to a healthcare provider.

Patients with liver disease, low blood pressure, or heart failure should use caution when taking Plendil. It is also essential to inform healthcare providers of all medications being taken, as Plendil can interact with other drugs, including beta-blockers, CYP3A4 inhibitors, and grapefruit products. Plendil should be stored in a cool, dry place below 25°C, away from heat and moisture. 

What Are the Uses of Plendil?

Plendil 5 mg tablets are commonly used to treat hypertension (high blood pressure).

What Are the Forms & Strengths of Plendil?

This medication comes in the following strengths and forms:

Tablets, Extended-release

• 2.5mg
• 5mg
• 10mg

What Is the Recommended Dosage of Plendil?

The dosage recommendations for Plendil may vary depending on various factors, such as the type and form of medication you take and the severity of your medical condition. Typically, the doctors may prescribe a starting dose and gradually adjust the doses as per your response to the treatment. It is important to note that your dosage recommendations may differ from those of other patients, so do not change them without consulting your medical professional. Here are some of the average dosage recommendations for different patients:     

Dosage for Adults

Hypertension (High Blood Pressure):

• Usual Dose: Start with 2.5 to 5 milligrams (mg) taken orally once a day.
• Maintenance Dose: 2.5 to 10 mg taken orally once daily; some experts suggest that up to 20 mg per day can be used if needed.

Hepatic Impairment (Liver Problems):

• Start with 2.5 mg taken by mouth once a day.

Dosage for Children

Hypertension (Off-Label Use):

• Start with 2.5 milligrams (mg) taken by mouth once a day.
• Do not exceed 10 mg taken by mouth once a day.

Dosage for Older Adults

Starting Dose: 2.5 milligrams (mg) taken orally once a day. The dosage should be adjusted based on how the patient responds to the treatment. Any increase in the dosage should be made at intervals of at least 2 weeks. The highest dose allowed is 10 mg taken by mouth once a day.

[Note: Remember, these recommendations may vary from person to person. Discuss it with your doctor, and they’ll customize your dosage accordingly.]

How Do You Take Plendil?

• Before you buy Plendil tablets online, read the instructions mentioned on your prescription label or medication guide.
• Take Plendil exactly as your doctor prescribes. Your doctor may adjust your dose from time to time.
• Plendil is typically taken once a day.
• You can take Plendil with or without food, but be consistent in how you take it each time.
• Swallow the tablet as a whole with a glass of water or as your doctor instructed.
• Do not crush, break, or dissolve it. Doing so may release the drug at once. 
• Regularly check your blood pressure during the course of your treatment.
• Continue using Plendil even if you feel well, as high blood pressure often shows no symptoms.
• Do not alter your dose or stop taking Plendil without consulting your doctor.
• Your treatment plan may include a healthy diet, regular exercise, weight management, and periodic blood tests.
• Maintain good dental hygiene by brushing and flossing your teeth regularly while taking Plendil.

[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They’ll adjust it as needed over time.]

How Does Plendil Work?

Plendil is a brand name for the medication felodipine, a calcium channel blocker. It works by relaxing the muscles of your heart and blood vessels. Specifically, it blocks calcium entry into the heart cells and bloodstream. This action widens blood vessels, reducing the pressure and making it easier for the heart to pump blood. As a result, Plendil is an effective option in treating hypertension (high blood pressure) and preventing chest pain (angina). By lowering blood pressure, it helps prevent strokes, heart attacks, and kidney problems.

Important Safety Information

What Are the Side Effects of Plendil?

Common Side Effects of Plendil: This medication can cause various side effects. While these effects are usually temporary, lasting from a few days to weeks, if left untreated, they can cause serious complications. So, if you suspect any reaction lasting more than the mentioned time period or gets intense over time, seek immediate medical assistance. Some of the common side effects of Plendil 5 mg tablets may include:

• Edema: When Plendil lowers your blood pressure, it relaxes blood vessels, allowing fluid to leak from blood vessels into surrounding tissues. As a result, you experience swelling on the hands, ankles, or feet (edema).  
• Headache: Many patients may experience headaches during their treatment with Plendil. These headaches may range from minor to severe and usually occur at the initial stage of the treatment. If the pain persists or gets intense, consult your doctor.
• Flushing (Feeling of Warmth): It is indicated by skin redness associated with a feeling of warmth. This side effect happens due to the increased blood flow to the various parts of the body, including neck, upper chest, or face. While this side effect is usually common, do not overlook it. Doing so may cause lead to potential risks.
• Dizziness: Relaxed blood vessels can slow down the blood flow, resulting in lower blood pressure. If your blood pressure drops drastically, the blood amount reaching to the brain lowers, leading to dizziness.
• Increased Heart Rates: When considering treatment with Plendil, be sure to monitor your heart rates, as you may experience increased heart rates. However, it is not a serious reaction, but if the condition worsens, talk to a medical professional.
• Hypotension: Like all blood pressure medication, Plendil can cause low levels of blood pressure. This usually happens due to lack of blood supply to the heart. So, if you notice significantly low blood pressure levels during your treatment with this medication, reach out to your doctor.
• Cough: This medication may lead to dry cough by impacting the functioning of your lungs and throat function. It is usually a common side effect but if it worsens over time, do not overlook and seek immediate medical attention.
• Nausea: Plendil may affect your digestion, leading to an uneasy feeling or making you nauseous. 
• Constipation: Felodipine may slow down your bowel movements, leading to constipation. It is common to experience this side effect at the start of your treatment.   
• Abdominal Pain: Stomach pain is among the common side effects of this medication. The drugs in Plendil can irritate the lining of your digestive system, making the digestion slower. If you suspect any cramping or pain in your abdomen after taking the medication that gets intense over time, seek medical assistance.
• Insomnia: It is a sleeping disorder in which you do not get quality sleep. If it is happening frequently, contact a medical practitioner.
• Joint Pain & Muscle Cramps: Drugs present in felodipine can affect oxygen supply in the joints and muscles, resulting in inflammation and tension in these areas. That’s why you may feel joint pain or muscle cramps during your course.  
• Increased Urination: Felodipine helps relax blood vessels, leading to increased blood flow through the kidneys. Due to this reason, your kidneys produce more urine than usual.   
• Common Cold: Many people may also experience cold symptoms, including stuffy nose, sneezing, and sore throat, during their treatment with this medication.

Serious Side Effects of Plendil: Other than the above side effects, Plendil can lead to various adverse reactions, causing life-threatening situations. Therefore, when you notice any unusual or unwanted side effects, do not overlook them and immediately contact your doctor. Some of the serious side effects of Plendil may include: 

• Gingival Hyperplasia: Also known as hypertrophy, gingival hyperplasia can cause swelling and enlargement of the gums. If you are noticing any of the following symptoms, reach out to your healthcare provider:
  • Gum bleeding
  • Foul breath
  • Pain in the gums
  • Plaque
• Allergic Reactions: Plendil contains various ingredients that can cause severe allergic reactions. Its symptoms may include:
  • Skin rash
  • Difficulty breathing
  • Feeling ill 
  • Swollen lymph nodes
  • Swelling on the mouth, lips, tongue, or throat
  • Dizziness or fainting
  • Nausea 
  • Difficulty swallowing
  • Stomach pain
  • Skin itching
  • Hives
• Palpitations: Plendil may cause irregular heartbeats, known as heart palpitations. If you notice that your heart is skipping beats, fluttering, or discomfort associated with chest pain, talk to your doctor right away.
• Upper Respiratory Tract Infection: In this side effect, your upper respiratory system, including the throat, nose, sinuses, and trachea, develops infections, which can get serious if left untreated. Its symptoms may include coughing, a stuffy nose, or a sore throat.
• Fainting: If you are taking Plendil, you may suddenly lose consciousness, which can be fatal in certain situations. So, talk to your doctor before considering treatment with this medication. 

[Note: Remember, this list may not cover all possible side effects. Always consult with your healthcare giver for medical advice about side effects.]

Are There Any Warnings for Plendil?

Yes, this medication has several warnings, which every patient must know before they decide to buy Plendil tablets online. Doing so may help avoid potential risks. Here are some of the important warnings:

• Patients with active or who have a history of liver problems should use this medication cautiously, as your body may not be able to metabolize the medication, which leads to drug buildup, causing severe side effects. To avoid such situations, inform your doctor before taking Plendil. If you are experiencing symptoms such as jaundice, fatigue, nausea, not feeling hungry, dark urine, pale stools, or skin itchiness and swelling, reach out to a doctor right away. 
• Discuss all other medications you are taking with your doctor, as many drugs can interact with Plendil.
• Calcium channel blockers, including Plendil, can cause severe low blood pressure, especially when suddenly standing up from a sitting or lying position. Therefore, it is important to regularly check your blood pressure and undergo any additional blood tests recommended by your doctor. Moreover, if you suspect any dizziness, lightheadedness, or fast heartbeats, call a medical professional immediately.
• Continue taking Plendil as prescribed, even if you feel well, since high blood pressure often shows no symptoms.
• Maintain good dental hygiene by brushing and flossing your teeth regularly to prevent mild swelling of the gums caused by Plendil.
• There is no specific data on how this medication may affect patients with heart failure. So, if you have any heart problems or are at risk of heart failure, inform your healthcare provider beforehand. They will suggest how Plendil may react to your medical condition and whether you need any special monitoring.
• Maintain good dental hygiene, as this medication can cause gum swelling or tender gums. To avoid this condition, frequently floss, brush, and visit your dentist at regular intervals. 
• Do not take this medication if you have lactose intolerance, as it may cause serious complications.

What Are the Plendil Precautions?

When considering treatment with this medication, you must follow certain preventive measures to avoid any potential risks. Here are some of the safety precautions that you can take before or while using this drug:

• Before using Plendil, tell your doctor if you have any allergies to felodipine or any of the components present in its formulation. The product may encompass inactive ingredients that can cause allergic reactions or other issues. Consult your pharmacist for more information.
• Share your medical history with your doctor or pharmacist, particularly if you have heart disease (such as heart failure), liver disease, or swelling of the arms and legs (edema).
• Inform your doctor or dentist about all the products you use, including prescription and nonprescription drugs and herbal products, before undergoing surgery.
• Felodipine may cause dizziness. It’s best not to drive, use heavy machinery, or perform any activity that requires alertness. Limit alcohol consumption and discuss the use of marijuana (cannabis) with your doctor, as these can increase dizziness.
• When you plan to buy Plendil online, consult a medical expert, as older adults may be more sensitive to the medication’s side effects, especially dizziness.
• Use this medication during pregnancy only if needed. Discuss the risks and benefits with your doctor.
• It has not yet been proven whether Prendil passes into breast milk. Thus, consulting a doctor before breastfeeding is advised.
• Avoid taking grapefruit juice while using this medication. Doing so may raise the felodipine levels in the body, causing adverse reactions. 
• Plendil is a prescription medication, so do not share it with other individuals, even if they have the same condition. Every patient has different body needs and a medical history; sharing your medications may lead to potential risks, which can be life-threatening.
• Patients have also reported cases of edema during their treatment with Plendil. So, if you notice any swelling on your face, legs, feet, or hands or fluctuations in your body weight, reach out to a medical expert.

What Are the Contraindications of Plendil?

Do not use calcium channel blockers, such as Plendil 5 mg, if you come under any of the following categories:

• Hypersensitivity: Do not take Plendil if you are allergic to any of the ingredients present in the medication’s formulation.
• Low Blood Pressure: Plendil should not be used in patients with low blood pressure.
• Heart Failure: Avoid using Plendil if you have heart failure.

What If You Miss a Dose of Plendil?

If you miss a dose of Plendil:

• Take the medication as soon as you remember. 
• However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. 
• Remember not to take two doses of Plendil at the same time. 
• Take the help of medication apps or set reminders on your mobile devices to avoid skipping any doses.

[Note: If you have missed a medication dose and are unsure when to take the next one, immediately consult your doctor or pharmacist.]

What Happens If You Take Too Much of Plendil?

Like all medications, Plendil can cause several overdose symptoms, which, if left untreated, may result in adverse situations. Some of the symptoms of a Plendil overdose may include a slow heart rate, low blood pressure, a feeling of warmth or tingling, and feeling light-headed as if you might faint.

[Note: If you consumed more than the recommended dose, get medical help immediately or call the Poison Help line at 1-800-222-1222.]

How to Store Plendil?

• Keep Plendil tablets in their original blister pack until it’s time to use them.
• Once removed from the blister pack, Plendil ER will not keep well.
• Store Plendil in a cool, dry place with a temperature below 25°C (77°F).
• Do not store Plendil or other medicine in the bathroom or near a sink.
• Keep Plendil away from heat and moisture, as these conditions can damage some medications.
• Do not leave Plendil in the car on hot days.
• Keep Plendil out of reach of young children. Store it in a locked cupboard at least one-and-a-half meters (about 5 feet) above the ground.
• Do not use the tablets if their expiration date has passed. The expiration date is usually the last day of the month mentioned on the back of the product’s label or carton.
• You should discard the medications in such a way that children & animals cannot consume them. If it happens, it may cause accidental overdose and death.
• You can eliminate unwanted medications by giving them in the medicine take-back program.

[Note: Discuss with your healthcare professional the proper disposal of unused medicine and any questions you may have regarding its storage.]

What Medications Interact with Plendil?

Drug interactions occur when you take two or more medications simultaneously. These interactions may either reduce the effectiveness of any of the medicines or affect the functioning of your medication. As a result, you can experience certain side effects, which can be life-threatening in certain cases. Here are some of the drug interactions that you should know before you plan to buy Plendil online:

• Beta-blockers: Concurrent use of beta-blockers may increase the risk of heart problems. Close monitoring is advised.
• CYP3A4 Inhibitors: Medications that restrict the CYP3A4 enzyme (e.g., certain antifungal drugs, macrolide antibiotics) can increase felodipine levels, potentially leading to side effects.
• Grapefruit Products: Grapefruit and grapefruit juice can alter how Plendil is metabolized, potentially leading to increased levels in the blood.
• CYP3A4 Inducers: Drugs that inhibit the CYP3A4 enzyme (e.g., rifampin) may decrease felodipine levels, reducing its effectiveness.
• Other Antihypertensive Medications: Concurrent use of other blood pressure-lowering medications may lead to excessive blood pressure reduction.
• Lithium: Felodipine may increase lithium levels in the blood, potentially leading to lithium toxicity.
• Digoxin: Concurrent use may lead to an increased risk of digoxin toxicity.
• Simvastatin: Co-administration with Plendil may increase simvastatin levels, potentially leading to muscle-related side effects.
• Ciclosporin: Felodipine may increase ciclosporin levels in the blood.

What Are the Other Plendil Interactions?

Other than the above drug, Plendil can also interact with medical conditions, lifestyle changes, and various herbs, supplements, and vitamins. These interactions are as follows:

• Grapefruit Juice: Consuming this juice while taking Plendil can raise the felodipine levels in the blood, thus increasing the risk of side effects. 
• Alcohol: Avoid consuming alcohol during your treatment with this medication, as it can raise the chances of developing side effects, especially low blood pressure, thus causing dizziness.
• Coronary Artery Disease: Patients with such conditions should talk to a medical practitioner before taking this medication, as it can affect the heart functioning.
• Liver Disease: People with damaged liver or any such diseases are unable to process the drug easily, leading to the extensive accumulation of these calcium channel blockers (CCBs). Moreover, some CCBs can also raise the liver enzyme, causing liver damage. 
• Hypotension: Do not use calcium channel blockers, including Plendil, in patients with severe low blood pressure or those experiencing cardiogenic shock. Doing so may reduce the heart’s ability to pump blood and lower blood pressure even more.    
• Congestive Heart Failure: Patients with CHF or those who have recently experienced heart failure should not use this medication, as it may have serious complications in the future.

[Note: This isn’t a complete list, and there could be other drugs that interact with Plendil. Make sure to tell your doctor about any prescription, over-the-counter medicines, and herbal products you’re taking.]

What Are the Plendil Alternatives?

Not every patient has the same medical needs. What suits one patient does not necessarily make an ideal option for the other. That’s why they use alternatives to avoid any potential risks. Patients who can not use Plendil can use the similar drugs mentioned below. 

• Norvasc (amlodipine)
• Cardizem, Tiazac (diltiazem)
• Procardia, Nifedical, Adalat (nifedipine)
• Isoptin, Calan, Verelan (verapamil)
• DynaCirc (isradipine)
• Cardene (nicardipine)
• Sular (nisoldipine)

[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.] 

Plendil Cost & Coupons

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Frequently Asked Questions

Is there an age limit for taking Plendil?

There is an age limit for taking Plendil, and those under 18 should abstain from using the medication due to potential risks and interactions with other medications. However, the specific age limit for taking Plendil should be determined by a healthcare professional based on an individual’s medical history and current health status. Always consult a doctor before starting or stopping any medication.

Does Plendil need to be taken with food?

Felodipine is typically recommended with a light, low-carbohydrate, and low-fat repast for optimal efficacy. It is important to adhere to the instructions given by your healthcare specialist since the dosage may vary. Furthermore, it is essential to remember that taking medication without food may lead to decreased absorption.

Can Plendil (felodipine) tablets be split in half?

You should not cut, split, chew, or crush Plendil (felodipine) tablets. They are designed as extended-release medications with a special coating. Cutting the tablet can damage this coating and alter the way the medication is released in your body. If you’re experiencing difficulty swallowing Plendil tablets, consult your healthcare provider to discuss alternative options.

Can Plendil (felodipine) lead to dry mouth?

Although it’s uncommon, a few individuals on Plendil (felodipine) have noted dry mouth as a side effect. If you experience dry mouth while taking Plendil, inform your healthcare provider. They may suggest methods to alleviate the discomfort, such as utilizing saliva substitutes, chewing sugar-free gum, or sipping water regularly throughout the day.

Is it safe to consume alcohol while taking Plendil (felodipine)?

It is advisable to avoid alcohol consumption when taking Plendil or other blood pressure medications. Regular alcohol intake can increase your blood pressure and reduce the effectiveness of Plendil and similar medications. Additionally, alcohol can exacerbate side effects like dizziness. If you find it challenging to eliminate alcohol entirely, consult your healthcare provider. They can offer support to help you quit or advise on a safer amount of alcohol for you to consume.

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