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Product Details

What Is Zaxine?

What Is Zaxine?

Zaxine (rifaximin) is a prescription medication used to treat hepatic encephalopathy and IBS with diarrhea (IBS-D). This oral antibiotic works in the intestines by stopping harmful bacteria from growing and producing toxins. Take Zaxine exactly as prescribed by your doctor, with or without food. The full course should be completed even if symptoms improve. Zaxine should be used cautiously in people with severe liver disease and is not recommended for certain age groups.

Quick Facts About Zaxine

Quick Facts About Zaxine

Product NameZaxine
Active IngredientRifaximin
Drug CategoryRifamycin Antibacterials
Available FormsTablets
Strengths Available550 mg
Routes of AdministrationTaken orally
Uses of ZaxineHepatic encephalopathy
IBS-D (Irritable Bowel Syndrome with Diarrhea)
Elimination Half-Life5.6 to 6 hours
Zaxine Storage15°C-30°C
PregnancyNot classified. Consult with your doctor.
Legal StatusRx only

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What Is the Drug Zaxine Used For?

What Is the Drug Zaxine Used For?

Zaxine 550 mg tablets are used to treat:

  • IBS-D (Irritable Bowel Syndrome with Diarrhea)
  • Hepatic encephalopathy
How Does Zaxine Work?

How Does Zaxine Work?

Zaxine (rifaximin) works in the gut by stopping certain bacteria from growing and making toxins. Since it is not absorbed much into the bloodstream, it stays in the intestines where it is needed. By blocking the bacteria’s ability to make RNA, it reduces harmful activity. For people with IBS-D, it helps calm gut bacteria, ease diarrhea, and reduce bloating. For those with hepatic encephalopathy, it reduces the amount of ammonia produced by gut bacteria. This helps prevent confusion and other serious problems.

How to Take Zaxine 550 mg Tablets?

How to Take Zaxine 550 mg Tablets?

If you want to use Zaxine for hepatic encephalopathy and IBS-D, follow these administration guidelines:

  • Take Zaxine 550 mg tablets exactly as prescribed by your doctor.
  • Swallow the Zaxine tablet whole with a glass of water.
  • You can take this antibiotic tablet with food or without food.
  • Try to take it at the same time each day to keep a steady routine.
  • Do not skip Zaxine doses, even if you start to feel better.
  • Finish the full course of treatment with Zaxine tablets unless your doctor tells you otherwise.
  • Do not share your tablets with anyone else.
  • Always follow your doctor’s instructions for how long to take the Zaxine tablets.
What to Do If You Miss a Dose of Zaxine?

What to Do If You Miss a Dose of Zaxine?

If you miss a dose of Zaxine, take it as soon as you can. If it is almost time for your next scheduled dose of Zaxine, skip the missed one. After that, continue with your regular Zaxine dosing schedule. Do not take two tablets at once to make up for a missed dose. Doing so may increase the risk of serious side effects of Zaxine.

What Happens If You Take Too Much Zaxine?

What Happens If You Take Too Much Zaxine?

If you take too much Zaxine, you may experience more side effects than usual. This includes nausea, stomach pain, or dizziness. However, serious problems from an overdose are rare because the drug is not absorbed much into the bloodstream. If you suspect a Zaxine overdose, contact the poison control center or your healthcare provider immediately.

What Are the Side Effects of Zaxine?

What Are the Side Effects of Zaxine?

Common Side Effects of Zaxine 550 mg TabletsRare or Serious Side Effects of Zaxine 550 mg Tablets
NauseaFluid buildup (ascites/edema)
VomitingUnusual bleeding or bruising
Abdominal painSevere muscle spasms or joint pain
DizzinessSevere allergic reactions
FatigueClostridioides difficile-associated diarrhea
HeadacheSevere liver problems (hepatic impairment)

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Zaxine Dosage Guide

Zaxine Dosage Guide

When considering Zaxine for IBS-D and hepatic encephalopathy, follow this table:

ConditionUsual Adult DoseDurationNotes
Zaxine for Hepatic Encephalopathy550 mg orally two times dailyLong-term, continuous useOften prescribed together with lactulose to reduce the recurrence of symptoms.
Zaxine for IBS-D (Irritable Bowel Syndrome with Diarrhea)550 mg orally three times daily14 daysIf symptoms recur, treatment may be repeated up to two times with the same regimen.

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Important Safety Information About Zaxine 550 mg Tablets

Important Safety Information About Zaxine 550 mg Tablets

  • Do not take Zaxine if you are allergic to rifampin, rifaximin, or similar antibiotics.
  • The safety of Zaxine during pregnancy and breastfeeding is not fully established, so it should only be used if clearly needed and under medical advice.
  • Zaxine 550 mg tablet is not recommended for children under 18 years for IBS-D.
  • Use Zaxine tablets with caution if you have severe liver impairment, as it may increase drug levels in the body.
  • If diarrhea, abdominal pain, or confusion return after treatment with Zaxine, consult your doctor.
  • Zaxine 550 mg tablets are not intended for prolonged use unless specifically instructed by your doctor.
How Should Zaxine Be Stored?

How Should Zaxine Be Stored?

You can follow these Zaxine storage guidelines for safe and effective use:

  • Store Zaxine tablets at room temperature, ideally between 15°C and 30°C.
  • You should keep the Zaxine tablets in their original bottle to protect them from moisture and light.
  • Do not store Zaxine in the bathroom or other damp areas. You should keep the Zaxine bottle tightly closed when not in use.
  • Don’t freeze it.
  • Always keep Zaxine out of reach of children and pets.
  • Do not use the Zaxine 550 mg tablets after the expiry date.
  • If the tablets are no longer needed or have expired, dispose of them safely. This should be done in accordance with the pharmacist's or local guidelines
Zaxine Interactions

Zaxine Interactions

Zaxine has relatively few known drug interactions. However, you should always inform your doctor about other medications you are taking. Common Zaxine interactions:

  • Allegra (fexofenadine)
  • Aspirin
  • Augmentin (amoxicillin/clavulanate)
  • Ativan (lorazepam)
  • Benadryl (diphenhydramine)
  • Celebrex (celecoxib)
  • Cymbalta (duloxetine)
  • CoQ10 (ubiquinone)
  • Cyclosporine
  • Eliquis (apixaban)
  • Fish Oil (omega-3 fatty acids)
  • Flagyl (metronidazole)
  • Lasix (furosemide)
  • Lyrica (pregabalin)
  • Metoprolol succinate
Zaxine Alternatives

Zaxine Alternatives

If Zaxine is unsuitable or unavailable, the following alternatives may be considered:

  • Zaxine Alternatives for IBS-D
    • Loperamide (Imodium)
    • Eluxadoline (Viberzi)
    • Cholestyramine
  • Zaxine Alternatives for Hepatic Encephalopathy
    • Lactulose
    • Neomycin
    • Metronidazole
  • Zaxine Alternatives for Intestinal Infections
    • Ciprofloxacin
    • Azithromycin
    • Trimethoprim-sulfamethoxazole
Why Buy Zaxine Online from Polar Bear Meds?

Why Buy Zaxine Online from Polar Bear Meds?

The high cost of Zaxine 550 mg tablets in the U.S. can be difficult for many people to manage. That’s why so many patients choose to buy Zaxine online from Polar Bear Meds. We help make treatment more affordable by offering this medication with a prescription at up to 80% lower cost than U.S. pharmacies. This is done without compromising safety or quality.

We source Zaxine 550 mg tablets for hepatic encephalopathy and IBS-D from licensed Canadian pharmacies. As a new customer, you can save even more by just using our Zaxine coupon code 'WELCOMEPB10' for an additional 10% off. You can expect Zaxine order delivery within 3-5 business days via our Xpress Post.

Important Disclaimer

Important Disclaimer

This content is intended to provide general information about Zaxine (rifaximin) and does not replace advice from a healthcare professional. Your treatment decisions should always be made in consultation with a licensed doctor or pharmacist. Your health conditions, medical history, and other medications can affect how Zaxine works and whether it is appropriate for you. Always follow your healthcare provider’s instructions. You should seek immediate medical help if you experience Zaxine’s serious side effects or worsening symptoms.

Zaxine FAQs

Zaxine FAQs

Learn more about Zaxine and related topics

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