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Mounjaro Vs Ozempic: Similarities and Differences

Mounjaro Vs Ozempic: Similarities and Differences

Mounjaro (tirzepatide) and Ozempic (semaglutide) are injectable medicines that aid in regulating blood glucose levels in people with type 2 diabetes. Both medicines have quickly become popular, thanks to their weight loss benefits. While Mounjaro and Ozempic offer similar benefits, key differences set both medications apart. In this blog, we will discuss all the similarities and differences to help you choose better between these medicines. Additionally, you can buy Mounjaro 2.5 mg online to control your blood glucose level effectively and maintain a healthy body weight.

How Does Mounjaro Work?

Mounjaro (tirzepatide) is an FDA-approved, once-a-week injection injected under the fatty tissue of your skin. It helps diabetes patients with type 2 control their blood sugar levels. Unlike other drugs, Mounjaro activates gut hormones that regulate blood glucose in those with type 2 diabetes: GLP-1 and GIP. The drug is recommended alongside individualized diets and exercise plans. It is currently only approved for treating type 2 diabetes. 

A 2022 study issued in The New England Journal of Medicine found that almost two-thirds of participants receiving 10 or 15 milligrams of Mounjaro injections once weekly reduced their body weight by 20% or more. In addition, eating a healthy diet and exercising regularly may help prevent cardiovascular (heart) problems in people with type 2 diabetes. The use of the medicine reduces blood pressure, which may decrease the chance of cardiovascular events such as heart attacks and strokes. Currently, it is not approved for heart problems.

How Does Ozempic Work?

Ozempic (semaglutide) is also an FDA-approved medication for treating type 2 diabetes in adults. When combined with diet and exercise, this drug helps control blood sugar levels. Healthcare providers generally prescribe Ozempic to people with type 2 diabetes and cardiovascular disease to decrease the chance of heart events like stroke.

It activates the body’s GLP-1 receptors, prompting the pancreas to produce insulin after eating and help regulate blood glucose levels in those having type 2 diabetes. A GLP-1 signal also tells your brain that you’ve eaten, making you feel full earlier and helping you lose weight.

The FDA has not authorized Ozempic as a weight loss drug, but it shows promise as a potential treatment for obesity. In a 68-week clinical trial published in the New England Journal of Medicine in 2021, Ozempic injections once weekly were found to reduce body weight, improve physical function, and lower heart disease risk factors.

What Are the Similarities Between Mounjaro and Ozempic?

The prescription medications Mounjaro and Ozempic are injected subcutaneously or under the skin once weekly. The following similarities exist between them:

  • Effectively controlling blood sugar levels in people with type 2 diabetes
  • Obese people can lose weight by promoting weight loss
  • It is possible to reduce Heart attacks and strokes by lowering the risk of major cardiovascular events

Besides these similarities, both have similar side effects, including vomiting, nausea, abdomen pain, diarrhea, constipation, and indigestion.

What Are the Differences Between Mounjaro and Ozempic? 

Mounjaro and Ozempic share many similarities, but they also differ significantly:

1. How They Work Biologically

Mounjaro is a GIP (glucose-dependent insulinotropic polypeptide) and a GLP-1 (glucagon-like peptide-1) receptor agonist. Ozempic, on the other hand, is only a GLP-1 receptor agonist, thus making it the first and only drug of its kind.

2. Efficacy

For controlling blood sugar levels and losing weight, Mounjaro injection is more productive than Ozempic. According to 2021 clinical trials published in The New England Journal of Medicine, 80% of participants who took Mounjaro reduced at least 5% of their body weight, and 36% lost more than 15%. 54% of Ozempic participants lost at least 5% of their body weight, while 8% lost more than 15%. A1C, the dimension of long-term blood glucose levels, was also significantly reduced by Mounjaro.

3. Benefits of Heart Health

With Ozempic, you can reduce the risk of major heart events, such as heart attacks, strokes, and death, especially if you have type 2 diabetes and cardiovascular disease. While Mounjaro is not currently approved for this use, it may reduce blood pressure and heart complications.

4, Dosage and Administration

The Mounjaro injection is a single-use device, meaning you must use a new pen for each injection. Depending on the prescription and how much your provider thinks you need, you can choose between 2.5 mg, 5mg, 7.5 mg, 10mg, 12.5 mg, or 15 mg of the drug. Ozempic is available in dosages of 0.25 mg, 0.5 mg, 1.0 mg, and 2.0 mg. One pen injector contains four doses equivalent to a month’s supply.

5. Cost

Mounjaro is typically more expensive than Ozempic. Medications vary in price based on dosage, insurance coverage, and manufacturer savings programs. Most insurance plans cover Mounjaro and Ozempic at least partially. Find out whether these medications are covered by your health insurance provider and insurance company. 

Is Mounjaro or Ozempic Better?

Your treatment goals and needs will determine whether Mounjaro or Ozempic are better. Ozempic is FDA-approved for preventing heart complications in those with type 2 diabetes and heart disease and is more effective at lowering blood sugar levels over three months (A1C).

Some people are more sensitive to the side effects of Mounjaro or Ozempic than others. As Mounjaro is more likely to cause nausea, vomiting, diarrhea, and stomach pain when taken at higher doses, people who are prone to gastrointestinal side effects may prefer Ozempic.

Talking to your healthcare provider is the best way to determine the proper medication. Depending on your individual health needs, they can help you weigh the advantages and disadvantages of each option.

Can You Switch from Ozempic to Mounjaro or Vice Versa?

You can switch between Ozempic and Mounjaro. Changing medications may be necessary if you are not seeing the desired results or experiencing side effects from the current drug. You should consult your healthcare provider before switching from one medication to another. Despite some similarities, these medications work differently and have different dosages. However, switching medicines requires careful consideration. Your healthcare provider will develop a safe and effective transition plan if changing medications is right for you. In addition, you can buy Mounjaro online at the best Canadian online pharmacy at discounted prices.


It is FDA-approved to prescribe Mounjaro (tirzepatide) and Ozempic (semaglutide), which can lower blood sugar in type 2 diabetics. When taking Ozempic, people with type 2 diabetes and heart disease are also at a chance of heart conditions like heart attack and stroke. Nevertheless, Mounjaro is better for weight loss and long-term blood sugar control.

Each medication requires an injection pen once weekly and offers similar benefits. If you have type 2 diabetes, discuss it with your healthcare professional about Ozempic or Mounjaro. Their expertise can aid you in choosing the proper medications for your body and creating a treatment plan that meets your needs.

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