Isophane Human Insulin  

Humulin

Humulin is FDA-approved for regulating blood glucose levels in individuals with diabetes mellitus. Humulin is the brand name of various insulin products, including Humulin R, Humulin N or insulin isophane (NPH), and Humulin 30/70. It contains insulin human, which works the same as naturally occurring insulin. Its dosage depends upon the patient’s needs, condition, and response to treatment. If you plan to buy Humulin insulin online, discuss your queries and concerns regarding the medication and let them know about your medical history and the medications you are using. Follow the directions given by your healthcare provider for a safe and efficient use of Humulin. 

Product Overview

Humulin is a line of insulin products designed to regulate blood sugar levels in patients with diabetes mellitus. It is suitable for treating both type 1 and type 2 diabetes in adults and type 1 diabetes in children. Humulin can also be used to manage hyperosmolar hyperglycemic state and diabetic ketoacidosis. However, it is not recommended for children under two years or for treating type 2 diabetes in children of any age.

Humulin has various forms, including Humulin R, Humulin NPH, and Humulin 30/70. Dosages vary based on individual needs and diabetes type, with adjustments made according to the patient’s response to treatment. Humulin aids glucose absorption from the bloodstream into cells, providing energy and stabilizing blood sugar levels. 

It’s essential to follow proper administration techniques, such as rotating injection sites and ensuring the correct dosage, to avoid complications like hypoglycemia or hyperglycemia. Common side effects of Humulin insulin include low blood sugar, itching, rashes, and swelling in the hands and feet. Patients should take precautions, such as regular blood sugar monitoring and avoiding alcohol consumption while on Humulin. When you order Humulin insulin online, consult a healthcare professional for personalized advice and dosage adjustments.

What Is Humulin Used For?

Humulin is used for the following conditions:

• To treat type 1 and type 2 diabetes in adults 
• To treat type 1 diabetes in children. 
• Hyperosmolar hyperglycemic state
• Diabetic ketoacidosis

[Important Warning: Humulin is not used in children below two years and children of any age to treat type 2 diabetes.] 

What Are the Forms & Strengths of Humulin?

This medication comes in the following forms and strengths:

Form: Humulin R

Strength: 100 IU/ml

Form: Humulin N (basal insulin)

Strength: 100 IU/ml

Form: Humulin 30/70 

Strength: 30% regular insulin and 70% isophane insulin

What Are the Recommended Dosages of Humulin?

Humulin comes in different forms and strengths; thus, its recommended dosages for different patients also vary. Doctors usually prescribe a starting dose of Humulin based on the patient’s weight, age, and type of diabetes and then adjust it accordingly (if needed). That is why consulting a medical professional before using Humulin for diabetes management is crucial for effective results. The following section includes the average doses of Humulin. If you have been prescribed a different dose, do not change it without consulting your doctor.

Dosage for Type 1 Diabetes 

• SC Initial dose: 0.2-0.4 units/kg/day 
• SC Maintenance dose: 0.5-1 unit/kg/day 

Dosage for Type 2 Diabetes

• SC Initial dose: 10 units/day 
• IV infusion: based on the patient’s age, condition, needs, and response to treatment.  

[Note: Remember, these recommendations may vary from person to person. Discuss it with your doctor, and they’ll customize your dosage accordingly.]

How to Administer Humulin?

Knowing the proper steps when considering treatment with Humulin is crucial for the safe and effective use of insulin. Here are some important guidelines on how to take this medication carefully:

• When you order Humulin insulin online, read your medication guide thoroughly and follow your doctor’s directions.
• Properly wash your hands with soap and water before administering the insulin. 
• Check the insulin for any unusual change in appearance. Do not use the medication if the solution appears discolored, cloudy, or has particles. 
• When injecting subcutaneously, you can inject the insulin into the stomach area, front thigh, upper arm, and buttocks. 
• Before administering the insulin, check if you have the correct type and brand of insulin. 
• You should carefully measure your dosage, as slight changes in the medication may lead to hyperglycemia or hypoglycemia. 
• Constantly rotate the injection spot each time you inject the medication to prevent getting lumps and pits under your skin. 
• Clean the injection spot with rubbing alcohol before injecting. 
• Inject the medication as directed by your doctor. 
• Do not rub the spot after injecting. 
• It is crucial to check your blood glucose regularly and share your report with your doctor to help them determine your correct dosage.
• Let your doctor know if your condition does not improve or worsen. 

[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They’ll adjust it as needed over time.]

What Is the Mechanism of Action of Humulin?

Humulin insulin is a short-acting insulin that starts to act within 30 minutes of injection, and its effect may last up to 8 hours. It helps glucose enter your bloodstream so your body can utilize it for energy. It suppresses glucose production in your liver and helps manage blood sugar levels.

Important Safety Information for Using Humulin

What Are the Side Effects of Humulin?

Common Side Effects of Humulin: Like all medications, Humulin also has several side effects. These temporary reactions generally stay for a few days or weeks and do not require immediate medical attention. However, if these effects persist for a long and intensify, reach out to your doctor. Some of these common side effects may include: 

• Low Blood Sugar: Humulin helps lower blood sugar levels, often causing hypoglycemia in certain patients. This usually happens because it aids the body in using glucose more effectively. Symptoms of mild hypoglycemia include shakiness, confusion, sweating, and weakness. This condition can be treated by eating quick sources of sugar like glucose tablets and monitoring blood levels regularly, which can help manage this side effect.   
• Itching & Rash: This medication can cause itching due to an allergic reaction to the insulin or the preservatives present in it. This side effect may become widespread and cause rashes. If the itching persists for a long time, talk to your doctor, or you can also use antihistamines for better relief.
• Injection Site Reaction: This medication can cause redness, swelling, or itching at the injection site. It usually happens when you use insulin at the same spot for a long time. This is not a severe side effect and can be managed easily by rotating injection sites. If the reaction continues, discuss alternate administration methods with your medical provider.
• Edema: This medical condition occurs when the fluid accumulates in the body’s tissues, causing swelling, especially on the hands and feet, along with other body parts. Swelling can further cause discomfort and difficulty with mobility in many patients. Reducing salt intake and using compression stockings may help manage edema.
• Blurred Vision: Humulin is used to lower blood sugar levels in patients with diabetes mellitus. This condition can affect your vision as the body struggles to get enough glucose to the eyes, leading to blurred vision. To minimize this risk, maintain stable blood sugar levels and have regular eye check-ups. 
• Rapid Heartbeat: Low blood sugar levels and fluid retention can sometimes cause rapid heartbeats in many patients. Its symptoms may include palpitations and a feeling of being lightheaded. If you are taking Humulin for diabetes management, frequently monitor your heart rate and sugar levels to manage this side effect. 
• Headache: Changes in blood sugar levels due to Humulin can cause headaches. The pain can be mild to severe and may be accompanied by other symptoms, such as dizziness. To avoid this risk, drink plenty of fluids, eat regularly, and manage stress.

Serious Side Effects of Humulin: Other than the common ones, Humulin can also cause certain adverse reactions. These side effects are severe and must be treated on time. If overlooked, it can become life-threatening. If you experience any unusual signs or symptoms after taking Humulin, seek immediate medical assistance. Some of these serious side effects may include:

• Severe Allergic Reaction: Humulin can cause severe hypersensitivity reactions, including anaphylaxis. This reaction happens within seconds or minutes of being exposed to something you are allergic to. It is a life-threatening side effect that requires immediate medical attention. Its symptoms may include: 
  • Difficulty breathing
  • Swelling of the face, lips, or throat
  • Rapid heartbeat
  • Shock (in rare cases)  
• Severe Hypoglycemia: Humulin can sometimes cause a drastic drop in your blood glucose levels, resulting in severe hypoglycemia. This can result in seizures, confusion, loss of consciousness, and even coma in extreme cases. While mild hypoglycemia can be treated at home, severe condition requires medical attention. If you can not visit a healthcare facility, use glucagon injection to reverse the effects.
• Heart Failure: Fluid retention is one of the common side effects of Humulin. Excess fluid retention can cause heart failure, especially in patients with pre-existing heart conditions. Some of its symptoms include fatigue, breath shortness, and swelling in the legs. If you experience any of these signs, contact your medical professional.
• Hypokalemia: Low blood potassium levels caused by Humulin can lead to muscle weakness, irregular heartbeats & cramps. In severe cases, hypokalemia can cause paralysis or respiratory failure. Monitoring potassium levels and adjusting diet or medication can help prevent this side effect.
• Peripheral Edema: Humulin can cause swelling in different body parts, especially in the hands, feet, and ankles, due to fluid retention. Peripheral edema can be uncomfortable and may require immediate medical attention. Reducing salt intake can help you avoid these symptoms. 

[Note: This list may not cover all possible side effects. Always consult with your healthcare giver for medical advice about side effects.]

Are There Any Warnings for Humulin?

Yes, Humulin can have several warnings that patients must be aware of before using this medication. Here are some important information that can help minimize the risk of potential complications:

• Do not share your syringes, injectable pen, cartridge, and needles with anyone, as it may spread infection from one person to another, causing life-threatening side effects. 
• You should not use Humulin during an episode of hypoglycemia. Doing so may exacerbate the condition due to extremely low blood sugar levels. It can further lead to symptoms like seizures, confusion, and even loss of consciousness. 
• All insulin products, including Humulin, may cause hypokalemia. If it is left untreated, it can lead to respiratory paralysis, ventricular arrhythmia, and ultimately death. 
• Humulin should not be used along with certain antidiabetics, such as Thiazolidinediones, as it may cause heart failure. 
• Stop using this medication immediately if you notice signs and symptoms of an allergic reaction, and contact your doctor at once.
• Do not change your dosage or stop or start a new insulin without consulting your doctor, as it may lead to unwanted side effects.
• Humulin can lead to low potassium levels in the blood. If you are already taking medicines to lower your potassium, you are highly likely to experience this side effect. To avoid this risk, consult a medical professional. They will monitor your potassium levels and give you medicines to maintain stable potassium levels.
• Patients with liver and kidney problems should inform their doctor before taking Humulin, as this condition may raise the chances of experiencing low blood sugar levels. If your medical providers are aware of this situation, they may adjust the dose accordingly to prevent hypoglycemia.
• You may develop lipodystrophy or injection-related scarring under the skin as a side effect of using Humulin N for diabetes management. Therefore, do not inject additional doses into the affected areas until your symptoms have been managed. 

What Precautions Should Be Taken When Taking Humulin? 

When considering treatment with Humulin, you must be aware of some preventive measures to avoid potential risks. These precautions are as follows: 

• If you are allergic to Humulin or its ingredients, inform your doctor before using it. 
• Before using Humulin, let your doctor know about your medical history, especially if you have a condition related to the heart, kidney or liver. Your doctor will decide whether or not this medication is safe for you to use. 
• Patients with renal or hepatic impairment may require frequent dosage adjustments and regular monitoring. 
• Tell your doctor if you think you are pregnant, planning to become pregnant or breastfeeding a baby. You may require an adjustment to your dosage to regulate blood sugar levels. 
• To ensure safe and efficient medication use, you should regularly check your blood sugar levels and share the report with your doctor. 
• To get the best results and maintain consistency, it is crucial to take the medication regularly.
• Do not consume alcohol while taking Humulin, as it may cause unwanted side effects. 
• Do not drive, operate heavy machinery, or indulge in activities that require your concentration unless you determine how this medication affects you. 
• Let your doctor know if your condition does not improve or worsens after receiving treatment from this medication.  
• Do not allow your Humulin to freeze. Do not use the insulin if it is frozen, as using a frozen insulin can be painful. 
• Discard it safely and get a new one from your pharmacist. 
• If you plan to buy Humulin online, check for any change in its appearance. Do not use the insulin if it is discolored, cloudy, or has particles. 
• You should constantly rotate the injection site to prevent lumps and pits from forming under your skin.  
• If you have high blood glucose levels, are sick, or exercise more than usual, inform your healthcare provider. You might require a dosage adjustment in your regimen. 
• Avoid skipping meals, as it can fluctuate your blood sugar levels.
• Always use the same brand and type of insulin unless your doctor advises otherwise. 
• Keep an additional supply of insulins, needles, and syringes with you at all times. 

What Are the Contraindications of Humulin?

Humulin is contraindicated for use in patients:

• During episodes of hypoglycemia
• Who has known hypersensitivity to Humulin, insulin isophane, or any of the inactive ingredients present in the medication? 

What If You Missed a Dose of Humulin?

• Maintaining consistency of the medication is very crucial for regulating blood sugar levels. 
• If you missed a dose of Humulin, check your blood glucose levels and decide accordingly. 
• If the blood sugar levels are in the normal range, you can skip the dose and take the next dose on time. If it is high, you should take it as soon as possible. 
• If it is almost time for the next dose, you can skip your missed dose and continue as per your regular dosing schedule. 
• Do not take two doses of the same medication to compensate for the missed dose, as it may cause hypoglycemia. 

[Note: If you have missed a medication dose and are unsure when to take the next one, immediately consult your doctor or pharmacist.]

What Happens If You Overdose on Humulin?

Overdose of Humulin may cause hypoglycemia, and if left untreated, it may lead to life-threatening hypoglycemia. Symptoms of overdose may include signs of severe low blood sugar, such as drowsiness, blurred vision, trouble speaking, seizure, and loss of consciousness. If someone has taken the medication more than recommended and has passed out, has difficulty breathing, has seizures, or can’t be woken up, immediately call 911 or head to the nearest emergency room.     

[Note: If you consumed more than the recommended dose, get medical help right away or call the Poison Help line at 1-800-222-1222.]

How Do You Store Humulin?

Proper storage is essential to maintain the safety and effectiveness of your medication. Below are some steps on how to store Humulin for effective results:

• Keep all insulins, including Humulin, away from the sight and reach of children. 
• Keep unopened Humulin in the refrigerator until its expiration date, but do not allow it to freeze. Do not use frozen insulin, as it can be painful. Safely discard it and get a new one from your pharmacist. 
• You may also keep Humulin at room temperature and use it within 28 days. Do not use it after 28 days, even if insulin is left in it. 
• Do not store the medicine in the bathroom or any place with moisture, as it may decrease effectiveness. 
• Keep the medication away from direct sunlight and excess heat. 
• Do not keep medications that are outdated or no longer needed. 
• Do not flush the medicine unless instructed to do so. 
• Do not throw the medication in wastewater or household garbage bins. 
• You can contact your healthcare provider or the local waste disposal company for guidance on safely disposing of the medication. 

[Note: Discuss with your healthcare professional the proper disposal of unused medicine and any questions you may have regarding its storage.]

What Medications Interact with Humulin?

Drug interactions happen when you take two or more medications simultaneously. This can either increase the risk of developing serious reactions or reduce the effectiveness of both medications. Therefore, if you plan to buy Humulin online, you must 

• Antidiabetic agents
• ACE inhibitors
• Alcohol
• Beta-blockers
• Antidepressants
• Certain antidiabetics
• Fluoxetine 
• Glucagon
• Quinine 
• Pentamidine
• MAOIs
• Antipsychotics
• Corticosteroids 
• Aspirin
• Diuretics
• Estrogens 
• Rosiglitazone
• Pioglitazone
• Protease inhibitors
• Thyroid hormones
• Reserpine
• Oral contraceptives
• Vorinostat 

What Are the Other Humulin Interactions?

Other factors like food, herbs, vitamins, and diseases can also affect the functioning of Humulin. If you plan to order Humulin insulin online, tell your doctor about the products you are using. These other interactions include:

• Alcohol: Consuming alcohol can affect your blood glucose levels, and you may experience hypoglycemia or hyperglycemia, depending on your alcohol intake. Patients with uncontrolled diabetes, high triglycerides, nerve damage, and pancreatitis should avoid alcohol during their treatment with Humulin.  
• Diseases: Isophane human insulin is not suitable for every diabetic patient. Taking this insulin while having the following medical problems can reduce the medication’s effects:
  • Renal/liver disease
  • Hypokalemia
  • Hypoglycemia

[Note: This isn’t the complete list, and there could be other drugs that interact with Humulin. Tell your doctor any prescription, over-the-counter medicines, and herbal products you’re taking.]

What Are the Humulin Alternatives?

Drug alternatives provide patients with additional treatment options, allowing them to choose the drug that better suits their individual needs. Similarly, many patients switch their Humulin treatment with other drugs when they are not getting the desired results. However, choosing drug alternatives to Humulin requires medical expertise. Your doctor will examine your condition & suggest a treatment suitable to your body’s needs. If you are curious to know the popular substitutes for Humulin, refer to the following list:

• Novolin R (insulin human)
• Fiasp (insulin aspart)
• NovoLog (insulin aspart)
• Apidra (insulin glulisine)
• Humalog (insulin lispro)
• Tresiba (insulin degludec)
• Levemir (insulin detemir)
• Lantus (insulin glargine)

[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.]

Humulin Cost & Coupons

The cost of Isophane human insulin, such as Humulin, is not the same everywhere. Various factors like location, health insurance plans, and pharmacies can influence the price range of Humulin. To help manage the inconsistent costs of insulin, many Americans reach out to Polar Bear Meds, where they can order Humulin insulin online at affordable prices without needing any medical claims. Additionally, first-time customers can avail themselves of extra savings by using coupon code “WELCOMEPB10” at the checkout. 

Frequently Asked Questions

Is there anything to avoid when taking Humulin?

The use of this medication should be avoided if you consume alcohol while taking it. Consuming alcohol when on this medication can increase your risk of experiencing hypoglycemia (low blood sugar), which is a dangerous condition.

Can you take Humalog and Humulin together?

Yes, you can take Humalog and Humulin together. The former medication contains insulin lispro as its active ingredient, which is a rapid-acting insulin. At the same time, Humulin contains insulin regular or NPH as its active ingredient, which is a short or intermediate-acting insulin. These medications are often used together to manage blood sugar levels more effectively. However, do not mix these insulins without consulting your medical provider. 

Does Humulin cause weight gain?

Yes, Humulin can cause weight gain in certain patients. When you use insulin like Humulin, it helps your body better use glucose for energy. However, extra glucose that is not used by the body gets stored as fat, resulting in weight gain. This is a common side effect of insulin medications and is something to be mindful of while managing your diabetes.

Is there a recommended time for taking Humulin insulin?

Humulin® I is a basal insulin that works continuously throughout the day to control blood glucose between meals. The most common time to inject Humulin® I is before bed, but the injection can be taken before breakfast or in the evening based on your needs. It is usually taken before bed, but you can also take it before breakfast or dinner.

Is Humulin Insulin available in a wide range of dosages?

The usual starting dose of Humulin R for type 2 diabetes is about 0.1 to 0.2 units per kilogram of body weight per day. For instance, if someone weighs around 68.2 kilograms (roughly 150 pounds), their initial Humulin R dose typically ranges from 7 to 14 units daily. Remember, 1 kilogram equals about 2.2 pounds.

Our Guarantee

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