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Product Details

What Is Amoxil (Amoxicillin)?

What Is Amoxil (Amoxicillin)?

Amoxil (amoxicillin) is a prescription antibiotic that belongs to the penicillin class, used for the treatment of a wide range of bacterial infections. It acts by inhibiting bacterial cell wall formation, which stops bacterial growth. Amoxil is available in several forms and strengths, including chewable tablets, tablets, capsules, and oral suspension. However, 250 mg and 500 mg capsules are currently available through our pharmacy.

Because misuse can lead to resistance or side effects, Amoxil should only be taken under a doctor’s supervision. Patients with a valid prescription may also explore licensed Canadian pharmacies to obtain Amoxil safely and potentially at a lower cost, depending on availability and location.


What Is Amoxil Used For?

What Is Amoxil Used For?

Amoxil is FDA-approved for the treatment of infections caused by susceptible bacteria. This includes:

  • Ear, nose, and throat infections (sinusitis, otitis media, pharyngitis)
  • Lower respiratory tract infections (bronchitis, pneumonia)
  • Genitourinary tract infections (cystitis)
  • Skin and skin structure infections
  • Helicobacter pylori infection (in combination therapy for duodenal ulcer disease)
Quick Facts About Amoxil

Quick Facts About Amoxil

CategoryDetails
Brand NameAmoxil
Generic NameAmoxicillin
Drug ClassPenicillin‑class antibacterial
FDA ApprovalFirst approved in 1974
Available FormsTablets, capsules, chewable tablets, oral suspension
Indications (FDA‑Approved Uses)- Ear, nose, and throat infections (sinusitis, otitis media, pharyngitis)
- Lower respiratory tract infections (bronchitis, pneumonia)
- Genitourinary tract infections (cystitis)
- Skin and skin structure infections
- Helicobacter pylori infection (in combination therapy for duodenal ulcer disease)
Warnings & Precautions- Serious allergic reactions (including anaphylaxis) in penicillin‑sensitive patients
- Clostridioides difficile–associated diarrhea
- Rare drug‑induced enterocolitis syndrome (DIES)
- Dose adjustment may be needed in renal impairment
StorageTablets/Capsules: Store at room temperature
Prescription StatusRx only

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Important Safety Information: Amoxil Precautions and Warnings

Important Safety Information: Amoxil Precautions and Warnings

What to Avoid While Taking Amoxil (Amoxicillin)?

  • Avoid combining Amoxil with other antibiotics or anticoagulants without medical supervision.
  • Do not use Amoxil for viral infections such as the common cold or flu.
  • Avoid skipping doses or stopping treatment early, even if symptoms improve.

What Are the Precautions of Amoxil?

  • Use with caution if you have a history of penicillin or cephalosporin allergy.
  • Patients with kidney impairment may require dose adjustment.
  • Long-term use may increase the risk of superinfection, including fungal or resistant bacterial infections.
  • Diarrhea may occur; report severe or persistent diarrhea to a healthcare provider.

What Is an Important Warning for Amoxil?

  • Serious hypersensitivity (allergic) reactions, including anaphylaxis, can occur and may be life-threatening.
  • CDAD (Clostridioides difficile-associated diarrhea) has been observed with antibiotic use and may occur during or after treatment.
  • Seek immediate medical help for rash, swelling, difficulty breathing, or severe diarrhea.

Who Should Not Take Amoxil (Amoxicillin)?

  • Do not take Amoxil if you:
    • Have a known allergy to amoxicillin, penicillins, or beta-lactam antibiotics.
    • Have experienced a severe allergic reaction like anaphylaxis to similar antibiotics.
Amoxil Dosage Chart

Amoxil Dosage Chart

Amoxil doses depend on the type and severity of the infection, age, and kidney function. Always follow your doctor’s dosage instructions and do not self‑adjust.

Amoxil Dosage for Adults

IndicationTypical DosageNotes
Mild to moderate infections500 mg taken every 12 hours or 250 mg every 8 hoursCommon for ear, nose, throat, genitourinary, and skin infections
Severe infections875 mg taken every 12 hours or 500 mg every 8 hoursUsed for pneumonia, severe sinusitis, or complicated infections
H. pylori eradication (duodenal ulcer disease)1 g twice daily with clarithromycin + proton pump inhibitorCombination therapy required
Maximum adult doseUp to 3 g/day, some indications allow higher under medical supervisionShould not exceed unless directed by the physician
Renal impairmentDose adjustment requiredLower or less frequent dosing depending on kidney function

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Amoxil Dosage for Children

IndicationTypical DosageNotes
General infections (>3 months old)20-40 mg/kg per day, divided every 8 hours or 25-45 mg/kg per day, divided every 12 hoursDose depends on infection severity
Otitis media (middle ear infection)80-90 mg/kg/day divided every 12 hours or 25 mg/kg/dose every 8 hoursHigh‑dose regimen recommended in resistant cases
Severe infectionsHigher end of dosing range (40-45 mg/kg per day)Determined by the physician
Infants (<3 months)30 mg/kg per day, divided every 12 hoursAdjusted for age and kidney function
Renal impairmentDose adjustment requiredPediatric dosing must be individualized

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What Is the Mechanism of Action of Amoxil?

What Is the Mechanism of Action of Amoxil?

Amoxil (amoxicillin) is a penicillin-class antibiotic that works by stopping the growth of bacteria. It inhibits bacterial cell wall synthesis by binding to PBPs (penicillin-binding proteins), which are essential for maintaining the bacterial cell wall. This action:

  • Weakens the bacterial cell wall
  • Causes the bacteria to rupture and die
  • Eliminates susceptible bacteria causing infection

Taking the full prescribed course is important to ensure complete infection clearance and reduce antibiotic resistance.


Amoxil Side Effects: Common, Severe, and Long-Term

Amoxil Side Effects: Common, Severe, and Long-Term

Most side effects of Amoxil capsules are mild and often resolve as the body adjusts to the medication. If you notice any adverse reaction during treatment, seek medical attention right away.

Common Side Effects of Amoxil

  • Nausea
  • Vomiting
  • Diarrhea
  • Rash
  • Loss of appetite

Amoxil Severe Side Effects (require immediate medical attention)

  • Serious allergic reactions (anaphylaxis, swelling of face/lips/tongue, difficulty breathing)
  • Severe skin reactions (Stevens‑Johnson syndrome, toxic epidermal necrolysis)
  • Persistent or bloody diarrhea (possible Clostridioides difficile infection)
  • Rare liver problems (yellowing of skin/eyes, dark urine, severe fatigue)
  • Seizures (rare, usually with very high doses or kidney impairment)

Amoxil Long‑Term Side Effects (with prolonged or repeated use)

  • Overgrowth of non‑susceptible organisms (including yeast infections)
  • Changes in gut bacteria leading to recurrent diarrhea
  • Rare liver enzyme elevations with extended use
Amoxil vs Other Antibiotics: Which Is Right for You?

Amoxil vs Other Antibiotics: Which Is Right for You?

Amoxil (amoxicillin) is a widely used penicillin-class antibiotic prescribed to treat many common bacterial infections. Other antibiotics may be chosen depending on the type of infection, bacterial resistance, allergies, and patient-specific factors. The table below compares Amoxil with other FDA-approved antibiotics:

FeatureAmoxil (Amoxicillin)Augmentin (Amoxicillin + Clavulanate)Keflex (Cephalexin)Zithromax (Azithromycin)
Drug ClassPenicillin antibioticPenicillin + beta‑lactamase inhibitorCephalosporin (1st gen)Macrolide
How It WorksInhibits bacterial cell wall synthesisSame as amoxicillin, plus clavulanate blocks resistance enzymesInhibits bacterial cell wall synthesisInhibits bacterial protein synthesis
Common UsesEar, nose, throat, respiratory, urinary, skin infections; H. pylori (combo therapy)Resistant respiratory/urinary infections, sinusitis, bite woundsSkin infections, strep throat, urinary tract infectionsRespiratory infections, skin infections, sexually transmitted infections
EffectivenessBroad spectrum, first‑line for many infectionsBroader coverage against resistant bacteriaEffective for Gram‑positive infectionsEffective for atypical bacteria (e.g., Mycoplasma, Chlamydia)
Safety NotesAllergic reactions possible; diarrheaMore GI upset due to clavulanateCross‑reactivity in penicillin‑allergic patientsQT prolongation risk; avoid in heart rhythm disorders
Who It’s ForPatients needing a first‑line, well‑tolerated antibioticPatients with suspected resistant infectionsPatients needing a cephalosporin alternativePatients allergic to penicillin or needing atypical coverage

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What Drugs Interact with Amoxil (Amoxicillin)?

What Drugs Interact with Amoxil (Amoxicillin)?

Amoxil (amoxicillin) has relatively few serious drug interactions, but some can be clinically important. This is not a complete list of Amoxil interactions, so tell your doctor before combining any medications:

Drug / ClassInteractionNotes
ProbenecidIncreases and prolongs blood levels of amoxicillin by reducing renal excretionCo‑administration not recommended
Oral Anticoagulants (Warfarin)May cause abnormal prolongation of prothrombin time (increased INR), increasing bleeding riskMonitoring and dose adjustment may be required
AllopurinolIncreased risk of rash when used with amoxicillinUse with caution
MethotrexateAmoxicillin may reduce the clearance of methotrexate, increasing the riskMonitor closely
Oral ContraceptivesMay rarely affect gut floraBackup contraception may be advised
Live Bacterial Vaccines (typhoid vaccine)Antibiotics may reduce the effectiveness of live vaccinesAvoid during treatment

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  • Always inform your provider about all medications, supplements, and vaccines you are using.
Amoxil Alternatives

Amoxil Alternatives

If Amoxil is not suitable for you, your doctor may recommend other antibiotics based on your infection type and medical history. Never switch antibiotics on your own.

  • Augmentin (Amoxicillin + Clavulanate)
  • Penicillin VK (Penicillin V potassium)
  • Omnipen (Ampicillin)
  • Zosyn (Piperacillin + Tazobactam)
  • Keflex (Cephalexin)
  • Ceftin (Cefuroxime)
  • Zithromax (Azithromycin)
  • Biaxin (Clarithromycin)
  • Levaquin (Levofloxacin)
  • Cipro (Ciprofloxacin)
Why Buy Amoxil from Polar Bear Meds

Why Buy Amoxil from Polar Bear Meds

Many patients rely on Amoxil capsules, a commonly prescribed antibiotic, to treat bacterial infections. Its safety and effectiveness are based on FDA-reviewed clinical studies and post-marketing data. Polar Bear Meds offers a convenient way to access Amoxil by partnering with a network of licensed Canadian pharmacies that adhere to strict dispensing and safety standards.

To make the experience easier for new customers, Polar Bear Meds offers a 10% discount on the first order with the coupon code WELCOMEPB10. All orders require a legitimate prescription from a licensed healthcare provider to ensure appropriate use and patient safety.

Polar Bear Meds is trusted by customers across the U.S. and Canada for reliable service, secure ordering, and responsive customer support. Orders include shipment tracking, and assistance is available by phone or email to help with prescription or order-related questions

Important Disclaimer

Important Disclaimer

Amoxil (amoxicillin) is a prescription antibiotic that must be used under the supervision of a healthcare provider. The information provided on this page is for educational purposes only & should not replace professional medical advice. Consult your doctor before starting Amoxil, and discuss potential side effects, risks, and possible drug interactions. Always follow your prescription label and consult your healthcare provider with questions about Amoxil use.

Amoxil FAQs

Amoxil FAQs

Learn more about Amoxil and related topics

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