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Upload your prescription.
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Cantharone Plus is a professional‑grade topical wart treatment used mainly by healthcare providers to remove stubborn warts, especially plantar warts and other resistant, heavily keratinized warts. Because of its potency, Cantharone Plus is applied only in a clinical setting by a licensed healthcare provider. Although it is not FDA-approved, it remains a commonly used treatment option among dermatologists. Cantharone Plus is a liquid wart‑removal formulation that contains:
| Product Name | Cantharone Plus |
|---|---|
| Active Ingredients | Cantharidin 1%, Salicylic Acid 30%, Podophyllin BP 2% |
| Drug Category | Topical Wart Removal Agent |
| FDA Approval Status | Not FDA-approved |
| Available Forms | Liquid solution |
| Strengths Available | 1%/30%/2% |
| Routes of Administration | Topical (applied by a healthcare provider) |
| Administration Frequency | As prescribed by the clinician, typically multiple applications with a blistering effect |
| Uses | Resistant plantar warts and other stubborn, keratinized warts |
| Pregnancy | Not Recommended |
| Use in Specific Populations | Not for children under 12 years |
| Storage | Store in a cool, dry place |
| Legal Status | Prescription/Professional Use Only |
| Manufacturer | Dormer Laboratories |
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Cantharone and Cantharone Plus are related, but they are not identical products. They differ in ingredients, strength, and clinical use. Cantharone and Cantharone Plus are topical wart-removal solutions that contain cantharidin. It is a blister-producing agent that causes the skin under a wart to lift and separate over time. Due to the risk of skin injury, both products are applied only by clinicians.
Key Differences at a Glance:
| Feature | Cantharone | Cantharone Plus |
|---|---|---|
| FDA approval | Not FDA-approved | Not FDA-approved |
| Cantharidin content | 0.007 | 0.01 |
| Additional active ingredients | None | Salicylic Acid (30%) and podophyllin (2%) |
| Overall strength | Moderate | Higher and more aggressive |
| Typical historical use | Common warts, periungual warts, molluscum | Resistant or thick plantar warts |
| Blistering potential | Expected but controlled | Higher due to the combination of agents |
| Who applies it | Healthcare professional only | Healthcare professional only |
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| Product | FDA Approval Status | Clinical Context |
|---|---|---|
| Ycanth® (cantharidin 0.7%) | FDA-approved | The only FDA-approved cantharidin product in the U.S. This product is approved for the treatment of molluscum contagiosum in adults and children who are 2 years and older. It is applied by a healthcare provider. |
| Cantharone | Not FDA-approved | A clinician-applied cantharidin solution, historically used for warts and molluscum. It does not have FDA approval or FDA-reviewed labeling. |
| Cantharone Plus | Not FDA-approved | A stronger cantharidin formulation with additional agents. It is also not FDA-approved and is meant for professional use in a clinical setting. |
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Cantharone Plus works by creating a controlled blister under the wart, which helps the abnormal skin lift away and fall off over time. Its main ingredient, cantharidin, is a blister-forming agent. When doctors use Cantharone Plus for plantar warts, the solution separates the wart from the deeper layers of the skin. The formula also contains salicylic acid, which softens and breaks down thick, hardened skin, and podophyllin, which damages rapidly growing wart tissue.
| Type | Side Effects Reported by Users | Notes |
|---|---|---|
| Common | Blistering at the treatment site (57%) | Expected effect: helps lift the wart |
| Redness or mild irritation | Usually temporary and resolves as the blister heals | |
| Pain or tenderness (7–85.7%) | Often occurs where a blister forms; it can last a few days | |
| Serious | Infection at the treated site (<1%) | Rare, but it can occur if the blister breaks or is not kept clean |
| Excessive swelling | Uncommon; may require medical attention | |
| Rare/Long-Term | Skin color changes; hyperpigmentation or hypopigmentation (1.8–53.3%) | Can last weeks to months; more likely in darker skin tones |
| Scarring | Very rare; usually associated with improper application or severe blistering | |
| Allergic reaction | Rare; may include severe redness, itching, or rash beyond the treatment area |
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Dormer Cantharone Plus wart removal solution is considered safe when used by a medical professional for its intended purpose. However, due to its additional ingredients, this topical solution carries certain risks. Here are some potential Cantharone Plus warnings:
When receiving Cantharone Plus wart treatment, patients are usually advised to follow these precautions.
If you are using Cantharone Plus for plantar warts, you can expect the following results, as mentioned in the Dormer Cantharone Plus wart removal information sheet. However, timing may vary slightly between patients.
| Feature | Cantharone Plus | Standard Salicylic Acid Treatments |
|---|---|---|
| Active ingredients | Cantharidin/Salicylic Acid/Podophyllin | Salicylic Acid only |
| FDA approval (U.S.) | Not FDA-approved | FDA-approved for wart removal (OTC) |
| Application | Applied only by a healthcare professional | Can be applied at home by patients according to label instructions |
| Speed of results | Often faster due to the combination effect | Slower; may take several weeks of daily application |
| Effectiveness for thick/resistant warts | More effective for stubborn, plantar, or keratinized warts | Less effective on thick or resistant warts |
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The choice of treatment depends on wart type, location, thickness, and patient preference. Always discuss with a dermatologist to choose the safest and most effective option.
U.S. customers can order Cantharone Plus from Canada, provided a valid prescription is submitted and verified before dispensing. All prescriptions are reviewed to ensure accuracy and compliance prior to order fulfillment.
Ordering Cantharone Plus online through a network of licensed Canadian pharmacies gives you safe and reliable access to your medication. When you buy Cantharone Plus online from Polar Bear Meds, you save up to 90% compared to most U.S. retail pharmacy rates. We offer competitive pricing to make wart removal treatment more accessible and affordable for patients.
When you order Cantharone Plus online from Polar Bear Meds, you get the following benefits:
Cantharone Plus is intended for professional use in clinical settings and is typically distributed through healthcare providers. This information is provided for educational purposes only. It does not replace professional medical advice. Availability and use may be subject to local regulations and professional guidelines.

Dr. Jackson Miller is a board-certified medicine physician & hospitalist. He is a healthcare professional with a strong background in patient care. With years of experience and a patient-first approach, he believes the foundation of good health is a patient who feels informed and empowered. He contributes to medical content review, drawing on his background in clinical practice and patient education. He focuses on presenting health information in a clear, accurate, and accessible way to help readers make informed decisions. His work emphasizes clarity, evidence-based guidance, and understandable explanations of medical topics.
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