Logo
Metformin ER - Image 1

Metformin ER

No packages found
price-match-guarantee

Price Match Guarantee

We offer competitive pricing on all our medications. Find a lower price? We'll match it from any verified Canadian online pharmacy! Know More

Similar Medications

How to Order

Ordering your medication online is simple and convenient.

STEP 01

Select the prescribed dosage and quantity, then proceed to checkout.

STEP 02

Sign in or create a new account.

STEP 03

Upload your prescription.

STEP 04

Complete your purchase by processing the payment.

Shipping takes approximately 3-5 business days.

Our Pharmacy Reviews

Read what our customers have to say about their shopping experience.

Product Details

Description

Metformin ER is a prescription drug that is widely indicated for managing high blood glucose levels in individuals with type 2 diabetes. This extended-release drug is used along with a healthy diet and exercise to achieve effective results. Unlike its immediate-release formulation, this medication is available in tablet forms and taken by mouth once daily. However, for appropriate strength tablets, people need to consult their doctor. They will prescribe the suitable strength of the medication that suits each individual’s condition and body’s needs. Many users can experience stomach discomfort while taking this medication, including diarrhea and nausea. To minimize this side effect, doctors generally recommend taking the tablets with the evening meal. Despite its benefits, Metformin ER may cause weight loss in certain people. Therefore, it is important to be aware of the medication's warnings and precautions to avoid potential side effects. If you are looking to buy Metformin ER online from Canada, you need to get a valid prescription from your doctor.

Metformin ER is an extended-release formulation primarily used to control high blood sugar in adults with type 2 diabetes. It contains metformin hydrochloride as its main ingredient, which works by minimizing glucose production in the liver, thus improving the body’s sensitivity to insulin and reducing the sugar amount absorbed from the food.

This medication is available as oral tablets and comes in various strengths, including 500mg, 750mg, and 1000mg. Doctors usually advise taking the medication once a day with the evening meal, ensuring slow absorption and maintaining blood glucose levels throughout the day. However, it is always the best idea to consult your medical provider before using this medication.

Despite its benefits, Metformin can cause several side effects, ranging from common to severe effects. While temporary reactions like nausea, diarrhea, and abdominal discomfort can be managed easily without needing immediate medical assistance, severe effects, such as lactic acidosis, low vitamin 12 levels, and allergic reactions, should not be overlooked and must be reported right away to a medical professional. If you plan to buy Metformin ER to manage diabetes, consult your doctor. They can guide you on the uses, doses, risks, and benefits associated with the medication’s use.

Uses and Benefits

Metformin ER manages high blood glucose levels in people with type 2 diabetes.

Dosage

What Are the Forms & Strengths of Metformin ER?

This medication is available in the form of oral tablets with the following strengths:

  • 500mg
  • 750mg, and
  • 1000mg

What Is the Recommended Dosage for Metformin ER?

The recommended dose for Metformin ER may vary depending on the individual’s age and severity of the condition. Doctors generally recommend a starting dose and then gradually increase it as per the response to the treatment. If you decide to buy Metformin ER to manage diabetes, you need to consult a medical expert for correct dosage recommendations. Here is the average dosing regimen of Metformin ER:

  • Initial Dose: Take 500 to 1000mg orally, once daily.
  • Dose Titration: Your doctor may increase the 500mg dose each week as tolerated.
  • Maximum Dose: Do not exceed more than 2000mg per day.

[Note: Remember, these recommendations may vary from person to person. Discuss it with your doctor, and they'll customize your dosage accordingly.]

Usage Guide

Correct medication administration is crucial to ensure its proper and safe use. If you plan to buy Metformin ER online from Canada or elsewhere, follow the below steps on how it should be taken properly:

  • Read the medication guide & follow the instructions exactly as they are mentioned.
  • Do not take more or less doses of your medication unless advised otherwise.
  • Take your medicine with an evening meal once a day.
  • Swallow the tablet as a whole with a glass of water.
  • Do not chew, crush, split, or break the medicine. Doing so may release the drug at once, increasing the risk of potential side effects.
  • If you are not able to swallow the medicine, talk to your doctor. They can prescribe you metformin oral suspension.
  • You may notice the medicine’s shell in your stool. This is normal because certain tablets are made with a shell that the body is not able to absorb or melt.
  • Take the medication at the same time each day to get the most benefit out of it.

[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They'll adjust it as needed over time.]

How It Works

Metformin helps reduce blood sugar levels in different ways. Primarily, it slows the absorption of sugar by the liver, which plays a major role in increasing blood glucose levels. The drug also helps the body respond better to the insulin it produces naturally. Since it is an extended-release formulation, there is no need to take the medicine multiple times a day. Its ER version is designed to be taken once daily, as it releases the drug slowly over time, helping manage blood glucose levels more steadily throughout the day. This gradual release prevents gastrointestinal effects, which are commonly associated with Metformin.

Side Effects

Common Side Effects of Metformin ER: Like all medications, Metformin can lead to various side effects. These reactions are generally temporary and may resolve on their own within a few days or weeks once your body adjusts to the drug’s effects. However, if they become severe or stay more than the mentioned period, talk to your doctor. Some of the common side effects of Metformin ER may include:

  • Diarrhea: It is one of the common side effects of Metformin that occurs due to the medication’s effects on gut bacteria, leading to certain digestive issues and causing diarrhea. This temporary side effect may subside within a few days or weeks. To avoid this effect, take the medicine with food, start with a low dose, and drink a lot of fluids.
  • Nausea: This side effect happens when Metformin irritates the stomach lining. Many users experience nausea during the initial stage of the treatment, but it is not a serious effect. It usually subsides within a few days or weeks with proper precaution. To avoid nauseous feelings, take your medicine with food, eat smaller meals, and avoid high-fat foods.
  • Low Blood Sugar: Metformin is used to reduce high blood sugar, but too much administration or high doses can drop the sugar levels significantly, causing low blood glucose. This side effect is temporary and can be managed if you follow your doctor’s instructions and eat regular meals.
  • Dizziness: This side effect can result from low blood sugar or dehydration caused by diarrhea. Users generally experience it at the start of the treatment. To avoid dizziness, stay hydrated, eat regular meals, and monitor your sugar levels. However, if the dizziness persists, talk to your doctor.
  • Headache: Metformin ER can lead to mild to moderate headaches due to changes in blood glucose levels or dehydration. This side effect is not serious and may subside within a few days or weeks. To reduce headaches, drink a lot of water, manage stress, and maintain a balanced diet.
  • Muscle Pain: Due to electrolyte imbalance, many people can experience muscle pain. This side effect is very common during Metformin treatment and may resolve on its own without needing immediate medical assistance. To reduce muscle pain, drink plenty of water, maintain a balanced diet, and include physical activity in your daily routine.
  • Stomach Pain: This is another common side effect of Metformin that results from an irritated stomach lining. Users may notice this pain after taking their medication, especially in the initial phase. Taking a low-dose tablet with food can help reduce the severity of the stomach pain.
  • Upset Stomach: Many users can notice an upset stomach during the start of their treatment. This temporary side effect subsides within a few days or weeks once your body adjusts to the drug’s effects. To avoid an upset stomach, take your medicine with food, eat small meals, and avoid high-fat foods. However, if the discomfort continues, talk to your medical provider.

Serious Side Effects of Metformin ER: Other than the above effects, this medication can cause certain severe side effects, which, if left untreated, can result in life-threatening situations. If you suspect any unusual signs, consult your medical provider right away. Some of the serious side effects of Metformin ER may include:

  • Lactic Acidosis: It is a rare side effect but can become fatal if overlooked. This side effect occurs due to lactic acid buildup in the blood, caused by various factors like kidney problems, liver issues, heart failure, or severe dehydration. If you notice symptoms such as vomiting, muscle pain, nausea, fatigue, or difficulty breathing, seek immediate medical assistance.
  • Allergic Reactions: This side effect results when your immune system falsely identifies the drug as a threat, causing severe hypersensitivity reactions. If you are taking Metformin and suspect allergic reactions like severe itching, rash, dizziness, or trouble breathing, contact your doctor right away.
  • Severe Hypoglycemia: Users can experience severely low blood sugar levels if they take Metformin ER in combination with insulin and other diabetes medicines or if they skip meals. Therefore, people using this drug should inform their doctor beforehand about the products they are using. While mild hypoglycemia can be managed by taking fast-acting sources of sugar, severe hypoglycemia should be reported immediately to a doctor. If you suspect symptoms like seizures, confusion, loss of consciousness, or coma, seek immediate medical attention.
  • Low Vitamin B12 Level: Prolonged use of Metformin ER can cause low vitamin B12 levels, which is necessary for nerve function & the production of red blood cells. Watch out for symptoms like weakness, fatigue, numbness, tingling in the hands and feet, or memory problems.
  • Irregular Heart Beat: While rare, this side effect can cause life-threatening situations if not treated in a timely manner. Metformin can fluctuate electrolyte levels or interact with other medicines, resulting in irregular heartbeats, also known as arrhythmias. If you are taking this medication, watch out for any changes in your heart rhythm.

[Note: Remember, this list may not cover all possible side effects. Always consult with your healthcare giver for medical advice about side effects.]

Are There Any Warnings for Metformin ER?

Yes, there are certain warnings associated with the use of this medication. If you plan to buy Metformin ER online from Canada or elsewhere, be mindful of the following warnings. This helps avoid any potential risks.

  • Menstrual Cycle Changes: Metformin ER may affect your menstrual cycle & increase the chances of pregnancy. If you are using any birth control pills while taking this medication, they may not work effectively. Consult your medical provider to avoid any risk. They will suggest some effective birth control methods during your treatment.
  • Folic Acid & Vitamin B12: Users taking Metformin ER are highly likely to experience low levels of folic acid and vitamin B12. To prevent this condition, ensure you take enough vitamins during your treatment.

Dehydration: Prolonged diarrhea or vomiting can lead to dehydration, increasing the risk of lactic acidosis. If you have been experiencing this side effect for a long time now, discontinue the use of Metformin and seek medical attention right away.

Warnings

Boxed warnings alert doctors & patients about the harmful effects of the medication. Metformin ER carries this warning, which highlights the risk of lactic acidosis. Here is the detailed warning:

Lactic Acidosis: This medication can cause lactic acidosis, which can even result in death in extreme cases. Its symptoms may include tiredness, muscle pain, difficulty breathing, drowsiness, and stomach pain. This condition happens when there is an excess of lactic acid in the blood. The risk is higher in people with the following conditions:

  • Kidney problems
  • Liver problems
  • Heart conditions
  • Addicted to alcohol
  • Undergoing procedures with contrast dyes or surgery
  • Taking other medicines like topiramate
  • Individuals 65 years of age and older
Safety Guide

When using any drug, you must know its safety precautions information. If you decide to buy Metformin ER to manage diabetes, be aware of the below safety guidelines:

  • If you are allergic to metformin or any ingredients present in its formulation, inform your doctor beforehand. The product may contain certain components that can cause severe allergic reactions.
  • People with upcoming surgeries or undergoing other medical procedures should tell their medical provider about the products they use. This includes all prescription drugs, nonprescription medicines, and herbal supplements.
  • If you have scheduled an x-ray or CT scan appointment using a dye that is injected into the veins, inform your medical provider that you are taking Metformin. They may temporarily stop your medication.
  • Do not use this medication if you have severe kidney disease, metabolic acidosis, and diabetic ketoacidosis. Therefore, sharing your complete medical history with your doctor is important. This helps prevent the risk of potential side effects.
  • Tell your doctor if you are also using insulin or other oral diabetes medications.
  • Stable blood glucose levels are important during pregnancy. Increased blood glucose levels can lead to complications in both the mother and the developing baby. So, if you are pregnant or planning to have a baby, consult a medical expert and follow their instructions. Discuss every risk & benefit associated with the use of Metformin during pregnancy.
  • Doctors may generally not recommend breastfeeding while taking Metformin. If you are a lactating woman, talk to your doctor. They will guide you on the benefits and risks of using the medication while breastfeeding.
  • This medication may cause hypoglycemia in certain patients, making them feel hungry, dizzy, irritated, confused, and anxious. To treat this condition, take a fast-acting source of sugar, such as hard candy, crackers, fruit juice, or non-diet soda.
  • For extreme or emergency cases, doctors may prescribe a glucagon injection kit. Learn how to use this kit in severe hypoglycemia cases.
  • Your glucose levels can be affected by stress, surgery, exercise, alcohol consumption, skipping meals, and illness. If you are suffering from or have any of these conditions, inform your doctor. They will change your dosage or medication schedule.
  • Metformin is only a part of the comprehensive treatment program. So, when using this medication, use it along with diet, exercise, weight control management, and special medical care.
  • Do not share your medication with other individuals, even if they have the same condition. This can raise the risk of potential side effects.
Contraindications

This medication is contraindicated in people with the following conditions:

  • Hypersensitivity to metformin hydrochloride
  • Severe renal impairment
  • Acute or chronic metabolic acidosis, particularly diabetic ketoacidosis
Missed Dose
  • If you missed a dose of your medicine, take it as soon as possible.
  • However, if it is close to the time for your next dose, skip the missed dose and continue your regular dosing schedule.
  • Remember not to take double doses simultaneously to make up for the missed dose. This can increase the risk of side effects.
  • Use medication apps or set timers on your mobile devices to avoid skipping any doses.

[Note: If you have missed a dose of your medication and are unsure about when to take the next one, immediately consult your doctor or pharmacist.]

Overdose

Taking more than the recommended dose of Metformin ER can lead to harmful effects. However, if you exceed the maximum daily dose, you may experience overdose symptoms like severe hypoglycemia or lactic acidosis. So, it is best to stick to the dosage as your doctor prescribes.

[Note: If you consumed more than the recommended dose, get medical help right away or call the Poison Help line at 1-800-222-1222.]

Storage Guide

A controlled environment is essential to maintain the long-term effectiveness of any medication. If you decide to buy Metformin ER from Canada, follow the below storage guidelines:

  • Store your tablets at a normal room temperature of 15°C to 30°C.
  • Protect the medication from extreme heat, light, and moisture.
  • Keep your tablets away from the sight and out of reach of children.
  • Discard the medicine when it is not in use or reaches its expiration date.
  • Ask a medical expert how to safely dispose of the medication without damaging the environment.

[Note: Discuss with your healthcare professional about the proper disposal of any unused medicine and any questions you may have regarding its storage.]

Interactions

Combining two or more drugs together can cause harmful effects, as it affects the functioning of the medication. Therefore, users are advised to always talk to their medical provider before co-administering any two drugs. If you plan to buy Metformin ER to manage diabetes, talk to a medical professional and be aware of the following drugs:

  • Acetazolamide
  • Cimetidine
  • Diatrizoate
  • Dichlorphenamide
  • Dolutegravir
  • Ethanol
  • Gatifloxacin
  • Iodamide
  • Iodipamide
  • Iodixanol
  • Iohexol
  • Iomeprol
  • Iopamidol
  • Iopromide
  • Iothalamate
  • Ioversol
  • Ioxaglate
  • Ioxilan
  • Levoketoconazole
  • Methazolamide
  • Metrizamide
  • Ranolazine
  • Topiramate
  • Zonisamide

What Are the Other Metformin ER Interactions?

Other than the above drugs, taking Metformin ER while having certain medical conditions can also cause adverse effects. These diseases are as follows:

  • Lactic acidosis
  • Liver disease
  • Renal dysfunction
  • Hypoglycemia
  • B12 deficiency

[Note: This isn't a complete list, and there could be other drugs that interact with Metformin ER. Make sure to tell your doctor about any prescription, over-the-counter medicines, and herbal products you’re taking.]

Alternatives

Drug alternatives provide a convenient option for users to switch from one treatment to another. This decision is influenced by many factors, including when people are not getting their desired results. While many drug substitutes are available in the market, it is important to talk to a medical expert. They will examine your condition & determine the most suitable alternative for you. Some of the popular drugs that you can take in place of Metformin ER are:

[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.]

Cost & Coupons

Metformin is an effective antidiabetic medication that helps control high blood glucose levels in people with type 2 diabetes, but its high retail prices can be a concern for many Americans. To manage these expensive costs, we at Polar Bear Meds provide affordable medications across the USA without needing any healthcare insurance plans. We also offer customers cost-saving coupons to help them manage their monthly medicine bills. If you reside in the USA, buy Metformin ER online with coupon code “WELCOMEPB10” and get a 10% discount on your first order.

FAQ

Guarantee

AtPolarBearMeds.com, we assure you the most affordable price of Metformin ER. Rest easy knowing that your order will be dispatched from a reputable Licensed Canada Pharmacy Online, adhering to the highest standards of quality and authenticity. Our discounted medications are shipped directly from Canada to your doorstep, ensuring a swift and secure delivery experience. To conveniently buy Metformin ER at a low cost, call us at1-888-779-2193toll-free.

Important Notice

The content provided on the Polar Bear Meds website serves to increase knowledge about healthcare products and medical conditions and is strictly for informational purposes. It should not replace professional medical advice. We urge you to consult with a qualified healthcare professional prior to utilizing any prescription or over-the-counter medication. Our platform grants access to an extensive array of products, sourced internationally, including Canada. We collaborates with a licensed pharmacy partner in Canada and trusted dispensing pharmacies globally. All affiliated fulfillment centers are accredited by the regulatory authorities of their respective countries.

Dr. Jackson Miller

Medically Reviewed by "Dr. Jackson Miller (M.D)"

Dr. Jackson Miller is a board-certified medicine physician & hospitalist. He is a healthcare professional with a strong background in patient care. With years of experience and a patient-first approach, he believes the foundation of good health is a patient who feels informed and empowered. He contributes to medical content review, drawing on his background in clinical practice and patient education. He focuses on presenting health information in a clear, accurate, and accessible way to help readers make informed decisions. His work emphasizes clarity, evidence-based guidance, and understandable explanations of medical topics.

Find Dr. Jackson Miller on:LinkedIn
Price matching guarantee certificate

We offer competitive pricing on all our medications. We'll match if you find a lower price on an identical product at a verified Canadian online pharmacy!

Eligibility Criteria:

  • The competitor's price must be active (no past/future sales).
  • It is only valid for Canadian online pharmacies with a verifiable address.
  • The product must match the strength, pack size, quantity, manufacturer & origin.
  • There are no price matches on used/expired medications.
  • You must submit your requests before placing an order.
  • We cannot adjust prices after purchase.
  • Request via live chat or phone before placing your order.

Need help? Call our friendly support team at 1-888-779-2193 or fill out the Contact Form