Insulin Isophane

Novolin GE NPH Penfill Cartridge

Novolin GE NPH Penfill Cartridge (Insulin Isophane Human Biosynthetic) is a specific form of insulin designed for use with insulin pens. It contains Neutral Protamine Hagedorn (NPH) insulin, an intermediate-acting insulin that helps regulate blood sugar levels. The Penfill cartridge is a convenient and easy-to-use option for individuals with diabetes who rely on insulin pens for their insulin administration. These cartridges are available in a strength of 3 ml (in a pack of five). Before injecting your insulin, check if the solution in the cartridge appears cloudy, and always mix it before use. Do not use it if you have low blood sugar or are allergic to any ingredients. Be aware of potential side effects like allergic reactions, heart failure, and lipodystrophy at the injection site. If you notice any adverse reactions, reach out to your doctor and adhere strictly to their guidance.

Product Overview

Novolin GE NPH Penfill Cartridges are designed for individuals with diabetes to help regulate their blood sugar levels. These cartridges contain a man-made, intermediate-acting insulin known as Novolin GE NPH, which is used with reusable insulin pens for easy administration. It is a type of basal insulin that works by imitating the natural insulin produced by the body. It helps absorb and store sugar from food, thereby managing high blood sugar levels in people with diabetes. The insulin takes about 90 minutes to start working, reaches its peak effect between five and eight hours, and lasts approximately 18 to 24 hours.

The dosage of Novolin GE NPH is personalized based on factors such as the individual’s blood glucose levels, diet, activity level, and overall response to the insulin. It is typically administered subcutaneously, one to three times daily, under the guidance of a healthcare professional. The insulin within the cartridges is expected to appear cloudy or milky, and it requires mixing before each injection to ensure an even distribution.

Unopened cartridges should be kept in the refrigerator, while opened cartridges can be stored at room temperature for up to 28 days. It’s important to protect the cartridges from direct heat and sunlight and to ensure they are used within their expiry date. Patients should be aware of the potential side effects, such as hypoglycemia (low blood sugar) and allergic reactions. It’s crucial to monitor blood sugar levels regularly and consult a healthcare professional if any adverse effects occur or if there are any concerns regarding the use of Novolin GE NPH Cartridges.

What Are the Uses of Novolin GE NPH Penfill Cartridges?

These Cartridges are designed to be used with a reusable insulin pen to:

• Control blood sugar levels in people with diabetes mellitus.

How to Take Novolin GE NPH Penfill Cartridges?

Here’s how to use your cartridges correctly:

• Check the Insulin: The insulin in your Novolin GE NPH Penfill Cartridge should look cloudy or milky. If it has settled at the bottom, that’s normal.
• Mix the Insulin: Before each use, gently rotate the cartridge up and down to mix the insulin evenly. Make sure the mixture looks uniform before proceeding.
• Prepare for Injection: This insulin comes in a 3 mL cartridge designed for use with your reusable insulin pen.
• Replace the Cartridge: After it is empty, replace it with a new one to continue your treatment.

[Note: Always follow the instructions provided by your healthcare provider and the manufacturer of your insulin pen before dosing NPH insulin.]

How Does Novolin GE NPH Cartridges Work?

Novolin GE NPH Penfill Cartridges are used with a reusable insulin pen to deliver a type of insulin called Novolin GE NPH. This insulin is similar to the insulin naturally produced by your body, but it lasts longer. Insulin is a hormone made by your pancreas, an organ near your stomach, and it helps your body use and store sugar from food. If you have diabetes, your body might not make enough insulin or use it properly, leading to high blood sugar levels. People with diabetes use Novolin GE NPH insulin to replace the insulin their body lacks. It is an intermediate-acting insulin, often referred to as basal or background insulin, because it helps regulate blood sugar levels throughout the day. This insulin contains small proteins called protamines that make it last longer. After you inject it, it starts working in about 90 minutes, reaches its peak effect between five and eight hours, and lasts for about 18 to 24 hours.

What Are the Precautions of Novolin GE NPH Penfill?

When using Novolin GE NPH Penfill, it’s crucial to adhere to the guidelines provided by your healthcare team to ensure safe and effective treatment. Here are some important precautions to consider:

• Allergy and Hypoglycemia Precautions:

1. 1. • Do not use Novolin GE NPH if you are allergic to any of its ingredients or if you currently have low blood sugar (hypoglycemia).
      • Allergic Reactions: Be aware of the signs of a severe allergic reaction, which can be serious and may require immediate medical attention. Symptoms include:
        • Sweating
        • Fast pulse
        • Shortness of breath
        • A rash over your entire body
        • Wheezing
        • Sudden drop in blood pressure
      • If you suspect an allergic reaction, contact your doctor immediately.

• Interaction with Thiazolidinediones (TZDs):

1. 1. • Taking Novolin GE NPH with diabetes medications known as thiazolidinediones (TZDs) can increase the risk of heart failure. This can occur even if you have no prior history of heart issues.
      • Be vigilant for symptoms of heart failure, such as:
        • Sudden weight gain
        • Shortness of breath
        • Swelling in your ankles or feet
      • If you experience any of these symptoms, it’s important to consult your doctor promptly.

• Injection Site Effects:

1. • Lipodystrophy: Repeated insulin injections at the same site may lead to changes in the fatty tissue under the skin, such as lumpy or hardened areas or an accumulation of fat. This can affect how your body absorbs insulin.
   • To prevent these issues:
     • Rotate your injection sites within the area you inject to give each site time to heal.
     • Talk to your doctor or diabetes educator about proper injection techniques to reduce the risk of lipodystrophy.

What Happens If You Miss a Dose of Novolin GE NPH Insulin?

If you miss a dose of insulin and there are more than 8 hours left until your next scheduled dose, you should take the missed dose as soon as you remember. It’s important not to double up on your next dose to make up for the missed one. Doubling the dose can lead to dangerously low blood sugar levels. Instead, continue with your regular dosing schedule and monitor your blood sugar closely.

[Note: If you have missed a dose of Novolin GE NPH Penfill Cartridge inhaler and are unsure about when to take the next one, immediately consult your doctor or pharmacist.]

What If You Take Too Much of Novolin GE NPH Cartridge?

Taking too much insulin can lead to an overdose, which is a serious medical emergency. Symptoms of an insulin overdose can include:

• Extreme weakness
• Blurred vision
• Sweating
• Trembling
• Stomach pain
• Confusion
• Seizures or convulsions

If you suspect an insulin overdose, seek immediate medical attention. Do not wait for symptoms to worsen. Treating an insulin overdose promptly is crucial to prevent severe complications, including loss of consciousness or even death. Always carry some form of sugar with you that can be quickly absorbed, such as glucose tablets or juice, to counteract low blood sugar until medical help is available.

[Note: If you consumed more than the recommended dose of Novolin GE NPH Penfill Cartridge inhaler, get medical help right away or call the Poison Help line at 1-800-222-1222.]

How to Store Novolin GE NPH?

Proper storage of Novolin GE NPH Penfill Cartridge is crucial to maintain its effectiveness. Here are the steps you should follow to ensure that your insulin remains safe and effective:

• Store Novolin GE NPH Penfill Cartridge in the refrigerator at 2°C to 8°C (36°F to 46°F) before opening. Avoid freezing. 
• Once in use, it can be kept at room temperature (below 30°C or 86°F) for up to 28 days. 
• Protect from direct heat and sunlight. Keep the cartridge in its original packaging until use. 
• Do not use it if it appears discolored or has particles. 
• Keep children and pets out of reach.

[Note: Discuss with your healthcare professional about the proper disposal of any unused cartridges and any questions you may have regarding its storage.]

What Can Interact with Novolin GE NPH Penfill Cartridge?

When using Novolin GE NPH Penfill Cartridge, it’s important to be aware of drug interactions that can affect blood glucose levels and insulin needs. Here’s a guide on what can interact with this insulin product:

Medications That May Cause Hypoglycemia (Low Blood Sugar)

• Other Diabetes Medications: When combined with Novolin GE NPH, other diabetes drugs may enhance the glucose-lowering effect, increasing the risk of hypoglycemia.
• Anabolic Steroids: Known to affect glucose metabolism, potentially lowering blood sugar levels.
• Beta-blockers: While they can manage blood pressure and heart issues, they may also mask hypoglycemia symptoms and occasionally contribute to lowering blood sugar.
• ACE Inhibitors: These are generally used for hypertension and heart failure and can enhance insulin sensitivity, thus lowering blood sugar.
• Monoamine Oxidase Inhibitors (MAOI): Can increase insulin sensitivity and prolong the hypoglycemic effects.
• Salicylates: Commonly found in medications like aspirin, they can increase insulin’s effects on lowering blood sugar.
• Sulphonamides: Used primarily as antibiotics, they can potentiate insulin-induced hypoglycemia.

Medications That May Cause Hyperglycemia (High Blood Sugar)

• Oral Contraceptives: Can affect carbohydrate metabolism, often leading to increased blood sugar levels.
• Thiazides: A type of diuretic which can reduce the effectiveness of insulin, leading to higher blood glucose.
• Glucocorticoids (such as cortisone): Widely known to increase blood sugar, especially in patients with diabetes.
• Thyroid Hormones: Increase overall metabolism, which can elevate blood glucose levels.
• Sympathomimetics: Drugs like epinephrine, salbutamol, and terbutaline are used primarily for asthma but can raise blood sugar.
• Growth Hormone: Has a counter-regulatory effect on insulin, often leading to elevated blood sugar.
• Danazol: An androgenic drug that can impair carbohydrate metabolism.
• Octreotide and Lanreotide: Used for treating certain hormone-related disorders, these can also raise blood sugar levels.
• Beta-blockers: Besides their potential to lower blood sugar, some can paradoxically increase blood sugar, depending on their specific pharmacodynamics and patient response.

[Note: This isn’t a complete list, and there could be other drugs that interact with Novolin GE NPH Penfill Cartridge. Make sure to tell your doctor about any prescription, over-the-counter medicines, and herbal products you’re taking.]

Novolin GE NPH Penfill Cartridge Alternatives

If you’re exploring alternatives to Novolin GE NPH Penfill Cartridge for managing diabetes, it’s a good idea to discuss this with your doctor. They can provide guidance on other medications that might be more suitable for your specific needs. For individuals with type 1 diabetes, insulin is essential because their bodies cannot produce enough insulin on their own. People with type 2 diabetes might also need insulin if other diabetes medications aren’t giving them the control they need, or if their bodies are no longer producing sufficient insulin.

Here are some different types of insulin that might be considered as alternatives to Novolin GE NPH Penfill Cartridge, whether for type 1 or type 2 diabetes:

• Fiasp (insulin aspart)
• Apidra (insulin glulisine)
• Admelog, Humalog, Lyumjev (insulin lispro)
• Afrezza (inhaled insulin human)
• Humulin R, Novolin R (insulin regular)
• Humulin N, Novolin N (insulin NPH)
• Toujeo, Lantus, Basaglar (insulin glargine)
• Tresiba (insulin degludec)
• Levemir (insulin detemir)

[Note: Your doctor will choose what’s the best alternative for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.] 

Novolin GE NPH Penfill Cartridge Coupons & Cost

Managing diabetes can be costly, particularly for those requiring Novolin GE NPH Penfill Cartridge without insurance coverage in the U.S. By choosing to buy Novolin GE NPH Penfill Cartridge online from Canada through Polar Bear Meds, you can significantly cut down on your medical expenses. We offer these cartridges at considerably lower prices, providing an economical option for U.S. residents. Use the coupon code WELCOMEPB10 at checkout to receive an extra 10% off your first order. Additionally, by participating in our referral program, you have the opportunity to save up to $200 on your medication costs. Polar Bear Meds is dedicated to making diabetes management affordable and accessible.

Frequently Asked Questions

Why is NPH insulin given at night?

NPH insulin is typically administered at night because it is an intermediate-acting insulin that peaks 8 to 12 hours after injection. By injecting it in the evening or right before bedtime, the insulin’s peak action coincides with the early morning hours when blood sugar levels naturally rise. This timing helps to effectively manage and lower fasting blood sugar levels (FBS) by the time you wake up in the morning. The goal is to optimize blood sugar control overnight, reducing the risk of high fasting glucose levels, which are a common challenge for people with diabetes.

What is the common side effect of Novolin GE NPH?

The most common side effect of using Novolin GE NPH, an insulin medication, is hypoglycemia, which means low blood sugar. It’s crucial to check your blood sugar levels regularly to avoid this issue. If not treated, low blood sugar can lead to serious problems like passing out, falling into a coma, or even death.

Can Novolin GE NPH Penfill be used in insulin pumps?

Novolin GE NPH Penfill is not recommended for use in insulin pumps. It’s an intermediate-acting insulin, and pumps typically require rapid-acting insulin for precise dosing. Consult your healthcare provider for suitable insulin options for an insulin pump.

What is the usual dosage of Novolin GE NPH?

The usual dosage of Novolin GE NPH varies depending on individual factors such as blood sugar levels, age, weight, and specific medical recommendations. It is crucial to follow the prescribed dosage provided by a healthcare professional for effective diabetes management.

Can older people use Novolin?

Yes, Novolin GE NPH Penfill can be used in elderly individuals. However, dosage adjustments may be necessary based on individual health and medical history. Consulting a healthcare provider is crucial to determine the appropriate insulin regimen for elderly patients.

Can I use Novolin if I have allergies?

If you have allergies, consult your healthcare provider before using Novolin GE NPH Penfill. They will assess your specific allergies and determine if this insulin is suitable for you. Inform them of any known allergies to insulin or its components for personalized guidance.

Our Guarantee

At PolarBearMeds.com, we assure you the most affordable price to buy Novolin GE NPH Cartridge from Canada. Rest easy knowing that your order will be dispatched from a reputable Licensed Canada Pharmacy Online, adhering to the highest standards of quality and authenticity. Our discounted cartridges and medications are shipped directly from Canada to your doorstep, ensuring a swift and secure delivery experience. To conveniently access Novolin GE NPH Penfill at a substantial cost, call us at 1-888-779-2193 toll-free.