Diltiazem hydrochloride 

Tiazac XC 

Tiazac XC is an FDA-approved calcium channel blocker medication used primarily for treating hypertension and angina. It contains diltiazem hydrochloride as its active ingredient. It functions by relaxing the blood vessels. It is available in the form of extended-release tablets with strengths of 120 mg, 180 mg, 240 mg, 300 mg, and 360 mg, typically taken once daily, with or without food. The medication dosage is based on the patient’s condition and response to treatment. For personalized guidance and recommendations, consult a licensed healthcare professional. You can buy Tiazac XC online from reputable sources with a doctor’s prescription.  

Product Overview

Tiazac XC contains the active ingredient diltiazem hydrochloride, a calcium channel blocker (CCB) used primarily to treat hypertension & angina. Diltiazem works by relaxing the blood vessels, which helps to reduce blood pressure & improve blood flow, thus relieving chest pain and preventing heart-related issues.

Available in extended-release capsules, Tiazac XC comes in various strengths, including 120 mg, 180 mg, 240 mg, 300 mg, and 360 mg. It is typically taken once daily, with or without food. Adults are the primary users, and the healthcare provider determines the exact dosage based on individual health needs and response to treatment. The extended-release formulation assures a gradual release of the medication over 24 hours, providing sustained effects. Common side effects of Tiazac XC may include headache, dizziness, fatigue, and swelling of the lower extremities. 

To minimize these effects, avoid abrupt changes in position and take the medication as prescribed. Adverse side effects should be reported to a healthcare professional immediately. Individuals should avoid grapefruit and grapefruit juice, as they can interact with diltiazem and increase its levels in the blood. If you have missed a dose, you should take it as soon as you remember unless it is close to the next dose. Do not double doses. In case of Tiazac XR overdose, seek immediate medical attention. Store Tiazac XC in a cool, dry place at room temperature, away from children and pets. Always follow your healthcare provider’s instructions and consult them before making any changes to your medication regimen.

What Are the Uses of Tiazac XC?

It is used to treat:

• Hypertension 
• Angina 

What Are the Forms & Strengths of Tiazac XC?

It is available in the form of extended-release capsules, which come in the following strengths:

• 120 mg 
• 180 mg 
• 240 mg 
• 300 mg
• 360 mg 

What Are the Recommended Dosage of Tiazac XC?

For Chest Pain 

• Adults- The initial recommended dosage is 120 mg once daily, preferably in the morning. Your doctor may make dosage adjustments as needed. 
• Pediatric Patients- Your doctor should determine the usage and dosage. 

For Hypertension

• Adults- The initial dose is 180-240 mg once daily, either in the morning or at night. Your doctor may make dosage adjustments as needed. 
• Pediatric Patients- Your doctor should determine the usage and dosage.  

[Note: Remember, these recommendations may vary from person to person. Discuss it with your doctor, and they’ll customize your dosage accordingly.]

How to Use Tiazac XC? 

• Before using Tiazac, you should carefully read and follow the instructions for use in the patient information leaflet and medication guide provided by your pharmacist or healthcare provider. Ask your physician or healthcare provider if you have any questions or concerns or need help understanding any part of the leaflet. 
• Use this medication exactly as your doctor directs. Do not use more or less of it, in large quantities or more frequently, as it raises the risk of unwanted side effects. 
• If you are switching to a different brand, strength, or form of diltiazem hydrochloride, you may need a dosage adjustment. 
• Your doctor may increase or decrease the dosage based on the patient’s medical condition, the response to treatment, and any other medication you may be taking or plan to take while using this medication. 
• Swallow the capsules whole. Do not crush, break, or chew them. Doing so can release all the medication at once and increase your risk of unwanted side effects. 
• You can also take the medication by carefully opening the capsule & sprinkling its contents on a spoonful of applesauce. You should immediately swallow the mixture without chewing, followed by a full glass of water to ensure complete swallowing. The applesauce should not be hot, and it should be smooth enough to be swallowed without chewing. 
• You should not store the applesauce mixture or capsule contents for future use; use them immediately. Subdividing the capsule’s contents is not recommended. 
• While using this medication, you should check your blood pressure and liver function regularly. 
• If you have high blood pressure, you should continue using the medication even if you feel well. Patients with hypertension don’t usually show symptoms. 
• To get the most benefit from your medication, try to maintain consistency in dosage and try to take it around the same time every day. 
• Getting the full benefit of Tiazac XC may take two to four weeks. 
• You should keep this medication away from light, heat, and moisture. 
• Inform your doctor if your condition does not get better or worsens. 

[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They’ll adjust it as needed over time.]

How Does Tiazac XC Work?

Tiazac XC, an antihypertensive and vasodilating agent, relaxes vascular muscles, thereby reducing blood pressure. This effect contributes to long-term therapeutic benefits, lowering the risk of cardiovascular events, including strokes & heart attacks. It’s used to treat mild-to-moderate high blood pressure and chronic stable angina (chest pain). The full effects may take 2 to 4 weeks to manifest. 

Important Safety Information for Using Tiazac XC

What Are the Side Effects of Tiazac XC?

Common Side Effects of Tiazac XC: Like other medications, Tiazac XC may cause side effects in some people. It is essential to mention that not everyone taking this medication will experience side effects. Most side effects caused by Tiazac XC do not require medical attention, may not be severe, and go away within a few days as your body adjusts to the medication. However, if they become bothersome or persist, contact your doctor. You can also talk to them to help prevent and manage these symptoms. The common side effects caused by Tiazac XC are as follows: 

• Headache
• Dizziness
• Fatigue
• Constipation
• Nausea
• Flushing
• Weakness

Mild Side Effects of Tiazac XC: To know more about the mild side effects of Tiazac XC, talk to your doctor or healthcare provider. Most of these side effects are not bothersome and do not usually require medical attention. However, you should consult your doctor if these symptoms persist or have become trouble. They are as follows: 

• Mild swelling of ankles or feet
• Slow heart rate
• Heartburn
• Dry mouth
• Skin rash or itching
• Sleep disturbances
• Loss of appetite
• Nervousness

Serious Side Effects of Tiazac XC: In rare cases, Tiazac XC may cause severe side effects in certain people. Severe side effects require prompt medical attention and may be life-threatening if not treated promptly. The following list does not include all severe side effects caused by this medication. You should report any new or worsening symptoms to your doctor. You can call 911 or head to the nearest emergency room if your symptoms are life-threatening. Serious side effects & their symptoms may include:  

• Severe allergic reactions, including anaphylaxis. Its symptoms may include hives, difficulty breathing, and swelling of the lips, mouth, tongue, face, or throat.
•  Heart rhythm problems such as irregular heartbeat or palpitations
• Sudden loss of consciousness, often due to a drop in blood pressure
• Difficulty breathing or feeling like you can’t get enough air
• Chest pain
• Severe dizziness, potentially affecting balance or daily activities
• Yellowing of skin or eyes, dark urine, or light-colored stools indicating liver problems
• Easy bruising or bleeding that’s difficult to stop
• Adverse skin reactions such as toxic epidermal necrolysis or Stevens-Johnson syndrome
•  Signs of liver issues such as persistent nausea, vomiting, abdominal pain, dark urine
• Significant changes in mood, including severe depression or suicidal thoughts
• Severe swelling, particularly in hands, feet, or ankles. 

[Note: This list may not cover all possible side effects. Always consult with your healthcare giver for medical advice about side effects.]

Are There Any Warnings for Tiazac XC? 

• You should not take this medication if you have any of the following conditions:
  • Are allergic to diltiazem or any of the medication’s ingredients
  • Certain heart rhythm problems  
  • Are or become pregnant 
  • Fluid in the lungs due to serious heart failure 
  • Very low blood pressure 
  • Prolonged heart rate 
  • Are taking the medication dantrolene 
  • Are taking the medication ivabradine 
• Senior patients may be at an increased risk of experiencing side effects of this medication, especially dizziness, constipation, or swelling ankles/feet. 
• You should use Tiazac XC during pregnancy only when it is clearly needed. You should only use this drug when its benefits outweigh the risks linked with its use. 
• Tiazac XC may pass into your breast milk and cause undesirable side effects on a nursing infant. Consult your physician or healthcare provider before breastfeeding while using this medication. 

What Are the Tiazac XC Precautions?

• Before taking this medication, you should tell your physician or healthcare provider if you have an allergy to Tiazac, diltiazem, or any other ingredient present in the product. You can ask your pharmacist or medical provider for the full list of ingredients. 
• Before taking Tiazac XC, you should tell your doctor if you have liver kidney, kidney disease, or congestive heart failure. 
• This medication may make you dizzy. Be cautious if you need to drive, operate heavy machinery, or engage in any such activities that require you to be alert. You should consult your doctor before discontinuing using the medication. If you stop taking Tizac abruptly, your condition may worsen. 
• This medication may only be part of a complete treatment program that also includes medication, diet, and exercise routine very carefully. 
• If you plan to have surgery, including a dental procedure, tell your doctor, surgeon, or dentist about all the medications you are taking, including all prescription, non-prescription, over-the-counter drugs, and herbal or vitamin supplements. 
• If you are receiving treatment with this medication for high blood pressure, you should continue using this medication even if you feel well. Your doctor may recommend you use blood pressure medications for the rest of your life. However, if you have symptoms of low blood pressure, such as fainting, dizziness, weakness, or blurred vision, immediately discontinue using this medication and contact your doctor.  
• The safety and efficacy of Tiazac have not been established in children, so you should consult a licensed healthcare provider before using it in children.  

What Are the Contraindications of Tiazac XC? 

Tiazac XC is contraindicated for use in patients who have:

• Sick sinus syndrome 
• Second or third-degree AV block 
• Severe hypotension
• Acute myocardial infarction with pulmonary congestion
• Severe left ventricular dysfunction
• Hypersensitivity to diltiazem or any other ingredient present in the medication
• Atrial fibrillation or flutter with an accessory bypass tract, specifically in Wolff-Parkinson-White syndrome or Lown-Ganong-Levine syndrome. 
• Ventricular tachycardia
• Pregnancy 
• Breastfeeding 
• Severe kidney or liver disease 
• Concurrent use of ivabradine 

What If You Missed a Dose of Tiazac XC?

• For optimal results, you should maintain consistency in dosage and take the medication around the same time every night. 
• If you have missed a dose of Tiazac XC, you should take it only if you have at least seven hours before waking up. 
• Otherwise, you may omit the missed dose and continue taking the medication according to the medication dosage schedule. 
• You should not simultaneously take double or extra doses of the same medication to compensate for the missed dose of Tiazac XC. 
• To further prevent missing doses in the future, you can try setting a medication reminder on your phone. 

[Note: If you have missed a dose of your medication and are unsure about when to take the next one, immediately consult your doctor or pharmacist.]

What Happens If You Take Too Much of Tiazac XC?

If someone has taken Tiazac XC more than recommended, you should immediately seek medical attention. If someone has overdosed on the medication and is experiencing serious side effects such as difficulty breathing, passing out, or seizures, immediately call 911 or poison control helpline. You can also head to the nearest emergency room. 

[Note: If you consumed more than the recommended dose, get medical help immediately or call the Poison Help line at 1-800-222-1222.]

How to Store a Tiazac XC?

• You should keep Tiazac XC in its original container, tightly closed in a dark and dry place. 
• Store the medication at room temperature, away from direct sunlight, moisture, and excess heat. 
• Do not allow the medication to freeze or expose it to extreme temperatures. 
• Keep all medications, including Tiazac XC, in a safe place away from the sight and reach of children and pets. 
• You should not keep medications that are outdated or no longer needed. Discard them safely. 
• You should not flush them down the toilet, pour them into the drain, or throw them in the household garbage bin. 
• You should dispose of unwanted medications in such a way that prevents children, animals, and other people from consuming them. 
• The best way to eliminate unwanted medications is to give them away in the medicine take-back program. 
• To learn how to dispose of unwanted medications, consult your pharmacist, healthcare provider, or local waste disposal company. 

[Note: Discuss with your healthcare professional the proper disposal of unused medicine and any questions you may have regarding its storage.]

What Medications Interact with Tiazac XC?

Certain medications may interact with Tiazac XC and affect how it may work. Before taking this medication, inform your doctor about all the medications you are currently taking or plan to take, including prescription, non-prescription, over-the-counter drugs, or herbal and vitamin supplements. This information will help them identify and prevent potential drug interactions. If you are concerned about Tiazac interactions, you should consult your doctor. This list is not complete, and there may be other drug interactions with Tiazac XR. 

• Abametapir
• Acalabrutinib
• Acebutolol
• Alfentanil
• Alprazolam
• Amiodarone
• Apalutamide
• Apixaban
• Aprepitant
• Armodafinil
• Atazanavir
• Atenolol
• Atorvastatin
• Avacopan
• Avapritinib
• Bedaquiline
• Belzutifan
• Benzhydrocodone
• Betaxolol
• Bisoprolol
• Bosutinib
• Brexpiprazole
• Brigatinib
• Budesonide
• Buprenorphine
• Capivasertib
• Carbamazepine
• Carteolol
• Carvedilol
• Celiprolol
• Cenobamate
• Ceritinib
• Cilostazol
• Cisapride
• Clarithromycin
• Clonidine
• Clopidogrel
• Clozapine
• Cobicistat
• Cobimetinib
• Codeine
• Colchicine
• Conivaptan
• Crizotinib
• Cyclosporine
• Dabigatran Etexilate
• Dabrafenib
• Dantrolene
• Daridorexant
• Darunavir
• Deflazacort
• Dexamethasone
• Dicloxacillin
• Digoxin
• Dihydrocodeine
• Dihydroergotamine
• Dipyrone
• Domperidone
• Doxorubicin
• Doxorubicin Hydrochloride Liposome
• Dronedarone
• Droperidol
• Elacestrant
• Elexacaftor
• Eliglustat
• Encorafenib
• Entrectinib
• Enzalutamide
• Epirubicin
• Eplerenone
• Erythromycin
• Eslicarbazepine Acetate
• Esmolol
• Etravirine
• Everolimus
• Fedratinib
• Fentanyl
• Fexinidazole
• Flibanserin
• Finerenone
• Fingolimod
• Fosaprepitant
• Fosnetupitant
• Gepirone
• Hydrocodone
• Ibrutinib
• Ifosfamide
• Infigratinib
• Itraconazole
• Ivabradine
• Ivacaftor
• Ivosidenib
• Labetalol
• Lacosamide
• Larotrectinib
• Lemborexant
• Lesinurad
• Levobunolol
• Lomitapide
• Lonafarnib
• Lorlatinib
• Lovastatin
• Lumacaftor
• Lumateperone
• Lurasidone
• Lurbinectedin
• Mavacamten
• Mavorixafor
• Melphalan
• Meperidine
• Methadone
• Metipranolol
• Metoprolol
• Mitapivat
• Mitotane
• Mobocertinib
• Morphine
• Morphine Sulfate Liposome
• Nadolol
• Nafcillin
• Naloxegol
• Nebivolol
• Netupitant
• Nilotinib
• Nirogacestat
• Olaparib
• Oliceridine
• Omaveloxolone
• Oxcarbazepine
• Oxprenolol
• Oxycodone
• Pacritinib
• Palovarotene
• Pemigatinib
• Penbutolol
• Pentazocine
• Pexidartinib
• Phenobarbital
• Pindolol
• Piperaquine
• Pixantrone
• Ponesimod
• Pralsetinib
• Prednisone
• Primidone
• Propranolol
• Ranolazine
• Repotrectinib
• Rifabutin
• Rimegepant
• Rivaroxaban
• Roflumilast
• Rufinamide
• Selpercatinib
• Selumetinib
• Simeprevir
• Simvastatin
• Siponimod
• Sirolimus Protein-Bound
• Sonidegib
• Sotagliflozin
• Sotalol
• Sotorasib
• Sparsentan
• St John’s Wort
• Sufentanil
• Suvorexant
• Tacrolimus
• Tazemetostat
• Telotristat Ethyl
• Tenofovir Alafenamide
• Tezacaftor
• Thioridazine
• Timolol
• Tolvaptan
• Topiramate
• Tramadol
• Ubrogepant
• Vemurafenib
• Venetoclax
• Venlafaxine
• Voclosporin
• Zanubrutinib
• Zolpidem 

What Are the Other Tiazac XC Interactions?

Apart from the drug interactions, Tiazac XR may also have certain interactions with herbs, supplements, food items, and beverages. This list may not be exhaustive, and you should always consult your healthcare provider or doctor for personalized advice. Significant interactions of Tiazac XR with herbs may include:

• St. John’s Wort
• Grapefruit juice
• Alcohol 

[Note: This isn’t a complete list, and there could be other drugs that interact with Tiazac XC. Tell your doctor any prescription, over-the-counter medicines, and herbal products you’re taking.]

What Are the Tiazac XC Alternatives?

People look for alternative medications to Tiazac XR when it does not suit them or produce the desired results. Many effective alternative medicines to Tiazac are available in the market. However, you should consult a licensed healthcare professional before changing your medication or starting a new one. They will help you determine which medication works best for you. Some of the popular medications are given below. 

• Plendil (felodipine)
• Felodipine (amlodipine)
• Adalat XL (nifedipine XL)
• Cardiazem (diltiazem)

[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.]

Tiazac XC Cost & Coupons

Tiazac XC is a medication used primarily for the management of hypertension and angina. Due to variations in health insurance coverage, many Americans face high out-of-pocket expenses when purchasing this medication. To help alleviate these costs, some turn to international pharmacies like Polar Bear Meds, which offer Tiazac XC at reduced prices. Additionally, new customers can benefit from the Tiazac XC coupon code WELCOMEPB10, providing a 10% discount on their first order. This option allows patients to manage their treatment more affordably while ensuring they receive the necessary medication without compromising their financial stability.

Frequently Asked Questions

How does Tiazac XC affect heart rate?

Tiazac XC, a calcium channel blocker, helps to decrease blood pressure by relaxing blood vessels & reducing the heart’s workload. This process often results in a decreased heart rate, as the heart doesn’t have to pump as forcefully. Patients should monitor their heart rate regularly and consult their healthcare provider to ensure Tiazac XC is functioning effectively without causing unwanted side effects.

Can Tiazac XC interact with other medications?

Yes, Tiazac XC can interact with various medications, including beta-blockers, digoxin, and certain antiarrhythmic drugs. These interactions may affect how well the medicines work or raise the risk of severe side effects. It is vital to inform your medical provider about all the medications, supplements, and herbal products you are using to manage potential interactions effectively and adjust dosages as necessary.

What should I avoid while taking Tiazac XC?

While taking Tiazac XC, avoid consuming grapefruit or grapefruit juice, as it can increase the medication’s levels in your bloodstream, leading to enhanced effects and potential side effects. Also, limit alcohol intake, as it can lower blood pressure further and amplify the drug’s effects. Always follow your healthcare provider’s advice regarding dietary and lifestyle restrictions to ensure the medication works safely and effectively.

What are the common side effects of Tiazac XC?

Common side effects of Tiazac XC include dizziness, headache, fatigue, and swelling of the hands or feet. These symptoms usually occur as your body adjusts to the medication. However, if they persist or worsen, it is essential to contact your healthcare provider. In rare cases, Tiazac XC can cause severe side effects like an irregular heartbeat or severe dizziness, requiring immediate medical attention.

Can Tiazac XC be used to treat conditions other than hypertension and angina?

While Tiazac XC is primarily prescribed for hypertension and angina, it is sometimes used off-label for other cardiovascular conditions, such as certain types of arrhythmias, or to prevent migraine headaches. However, these off-label uses should only be considered under the guidance of a healthcare provider, as the safety and efficacy for these conditions may not be as well-established as for its primary indications. Always discuss with your doctor before using Tiazac XC for any off-label purposes.

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