Tresiba FlexTouch

Tresiba Flextouch pen 200 Units ml is an FDA-approved long-acting insulin that improves glycemic control in adults and children aged one year or older with type 1 and type 2 diabetes mellitus. It contains insulin degludec, which mimics the pharmacokinetic profile of endogenous insulin and maintains blood sugar levels throughout the day. It is contraindicated for use in patients during hypoglycemic episodes and in patients with a known hypersensitivity to insulin degludec or any inactive ingredient present in Tresiba Flextouch. If you have any queries regarding dosage, storage, and potential risks and benefits of the medication, consult your doctor or healthcare provider. 

Tresiba FlexTouch 200 Units/ml is a long-acting insulin containing insulin degludec, which is used to control fasting blood sugar levels in patients with type 1 and type 2 diabetes mellitus. It maintains steady insulin levels for up to 42 hours, mimicking the natural pattern of insulin release in the body. The strength of Tresiba FlexTouch is 200 Units/ml, available in a 3 ml single-use pen. It is administered via subcutaneous injection into the abdomen, thigh, or upper arm. The dosage is highly individualized and should be decided by a healthcare provider based on the patient’s age, weight, and specific insulin requirements. 

Tresiba FlexTouch is suitable for adults and children, including those aged one year and older, under the guidance of a healthcare provider. It helps regulate blood glucose levels by facilitating the absorption of glucose from the bloodstream into cells, thereby reducing high blood sugar levels. Common side effects of Tresiba FlexTouch include hypoglycemia, injection site reactions, and weight gain. It is vital to monitor blood glucose levels on a regular basis and be aware of the signs of hypoglycemia.

Precautions should be taken in patients with liver or kidney disease, and alcohol consumption should be limited. If a dose of Tresiba FlexTouch is missed, it should be taken as soon as remembered, with at least 8 hours between doses. In case of overdose, immediate medical attention is required. Unopened Tresiba FlexTouch should be stored in the refrigerator and at room temperature after opening, away from direct heat and light. Proper disposal of needles is essential to prevent accidental needlestick injuries.

It is used to:

• Improve glycemic control in patients with type 1 and type 2 diabetes mellitus.

[Important Warning: Tresiba Flextouch is not recommended for treating diabetic ketoacidosis.]

Tresiba Flextouch is available as a pre-filled 3 ml single-patient use pen injected subcutaneously (under the skin), available in the strength of:

• 200 IU/ml

What Is the Recommended Dosage for Tresiba Flextouch 200 Units/ml?

The dosage of Tresiba Flextouch 200 units ml is based on the patient’s medical condition, needs, and response to treatment. The general guidelines are given below. If your doctor has prescribed you a dose different from the one given below, you should not change it and follow your doctor’s instructions very carefully.

Recommended Dosage of Tresiba for Adults with Type 1 Diabetes

Insulin naïve: The initial dose is ⅓–½ of the total daily insulin dosage. 

Already on insulin: The initial dose should be the same as the current basal insulin 

Recommended Dosage of Tresiba for Adults with Type 2 Diabetes:

Insulin naïve: The initial dose is 10 units daily.

Already on insulin: The initial dose should be the same as the current basal insulin

Recommended Dosage for Pediatric Patients:

Insulin naïve (Type 1 diabetes): The initial dose is ⅓–½ of the total daily insulin dosage.

Insulin naïve (Type 2 diabetes): The initial dose is 10 units daily.

Already on insulin: 80% of the total current basal insulin. 

[Note: Remember, these recommendations may vary from person to person. Discuss it with your doctor, and they’ll customize your dosage accordingly.]

To use the Tresiba FlexTouch, you’ll need to learn proper injection techniques, dosing, and storage. Always consult an expert healthcare professional for personalized guidance and instructions, as proper use is crucial for effective diabetes management and avoiding complications. With a little practice, using the Tresiba FlexTouch can become an uncomplicated part of your daily routine. Your doctor will show you how to administer the injection the first time. Make sure you and your caregiver understand how to inject the insulin properly. Here is a step-by-step guide on how to administer Tresiba Flextouch pen 200 units ml effectively: 

• Before you start using the Tresiba Flextouch, you should carefully read and follow the instructions for use given in the patient information lealfet & medication guide provided by your medical giver. If you have any queries or concerns regarding the medication usage or if you have difficulty understanding any part of the leaflet, you should consult your doctor.
• Before using the insulin, properly wash your hands and check the insulin for any change in appearance. Do not use Tresiba if the insulin appears to be cloudy, has changed its color, or has particles in it. Discard it safely and get a new one from your pharmacist.
• Do not dilute or mix the insulin with other medications.
• You should not administer insulin degludec in an insulin pump or intravenously.
• Tresiba Flextouch 200 unit ml insulin pen should be used cautiously in patients who have visual impairment that may rely on audible clicks to dial the prescribed insulin dose.
• Clean the injection spot with rubbing alcohol and a cotton swab or soap and water before injecting the dose, and let it dry before you inject the insulin. Rotate the injection site every time you inject the insulin to reduce the risk of lumps and rashes. Do not inject into skin that is torn, swollen, red, or has stretch marks or wounds. Do not inject cold insulin, as it may be painful. 
• Tresiba Flextouch is for subcutaneous use only. The best sites to inject the insulin are the abdomen, upper arm, and front thighs. Do not inject it into a muscle or vein.
• Check the label of your prescription to ensure you have the correct type of insulin and dosage. Do not convert the prescribed dose into any other unit. 
• Select the prescribed dosage on the dial. Use a new needle to inject the medication.
• Prime your insulin pen by selecting two units and holding the dose button until the dose counter shows 0. Ensure a drop appears.
• Insert the injection into the skin. Press and hold the dose button.
• After the dose counter reaches 0, start counting to 6 to ensure the complete insulin dosage is delivered.
• After administering the insulin, remove the pen needle and throw it away safely in an FDA-approved sharps container.
• Replace the pen cap and wash your hands.
• Use this medication consistently to get the best results. To help you remember, try to take the insulin at the same time each day.
• Regularly check your blood glucose levels to know the progress and how your body is responding to the treatment. Share the report with your doctor.
• You should not use a syringe to remove insulin degludec from the Tresiba Flextouch 200 unit ml.
• Tell your doctor if your condition does not get better or if it worsens.
• Do not share your needles, syringes, and pre-filled pens with others, even if they have the same condition as you.
• Keep Tresiba Flextouch 200 Units/ml in its original packaging in a cool & dry place, away from excess heat, moisture, and direct sunlight.

[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They’ll adjust it as needed over time.]

Tresiba Flextouch contains insulin degludec, which is a synthetic insulin that works the same way as the insulin that is naturally produced by your body. When you inject the insulin right under your skin, it gets absorbed into your bloodstream. It replaces the natural insulin and reduces the blood sugar levels in your body. It maintains steady insulin levels for up to 42 hours. It helps maintain glycemic control in individuals with diabetes mellitus.

What Are the Side Effects of Tresiba Flextouch 200 Units/ml?

Similar to other medications, Tresiba may also cause certain side effects in people using it. It is also important to mention that not everyone using insulin degludec will experience these side effects. Most of the side effects caused by Tresiba Flextouch 200 Units ml do not require medical attention and disappear within a few days as your body adjusts to the medication. Common Side Effects of Tresiba Flextouch 200 Units/ml may include:

• Hypoglycemia or low blood sugar: It occurs when the levels of blood glucose fall below the normal range of 70 mg/dl. Its symptoms may include sweating, shakiness, confusion, dizziness, irritability, and in severe cases, passing out. 
• Weight gain: Insulin degludec can promoto storage of fat and fluid retention, which duther causes weight gain. This is more likely to occur when you initially begin using Tresiba Flextouch 200 Units/ml.
• Injection site reactions: Its symptoms may include localized irritation such as rash, itching, or redness at the spot where the injection was administered. To avoid this, you should always rotate the injection site. 
• Lipodystrophy: It refers to the fat tissues changes at injection sites, leading to lipohypertrophy (lumps) or lipatrophy (depressions) under the skin area. This can affect glycemic control and insulin absorption of the patient. 
• Headache: A common side effect of Tresiba can include pain or discomfort in the head, neck, or scalp. The exact mechanism leading to headache is not known. 
• Diarrhea: The exact cause in relation of frequent, loose, watery stools to insulin use is not clear but this could be related to changes in metabolism or gut mobility.
• Nasopharyngitis, commonly known as cold, is the inflammation of the nasal passages and pharynx. Its symptoms may include sore throat, nasal congestion, and sneezing.

Tresiba Flextouch 200 Units ml can sometimes cause mild side effects in some people using it. Usually, these side effects are not serious and disappear on their own without medical assistance. However, if these side effects are bothersome or still persist, you should tell your doctor immediately. Mild side effects of Tresiba Flextouch 200 Units/ml are as follows:

• Dizziness: This may be related to changes in blood sugar levels or other factors. It includes lightheadedness or unsteadiness.
• Nausea, which may lead to vomiting. This could be due to changes in metabolism or as a secondary effect of hypoglycemia.
• Stomach discomfort, including bloating, cramps, indigestion, or general abdominal unease.
• Fatigue or lack of energy. This could be related to changes in blood sugar levels or metabolism.
• Increased appetite: This enhanced desire to eat can potentially lead to fluid retention or changes in electrolyte balance.

In rare cases, Tresiba Flextouch 200 unit ml can cause severe side effects in people belonging to certain groups. It is important to mention that your doctor has prescribed you this medication because they have determined that the benefits caused by this medication outweigh the risks associated with its use. If you are concerned about any side effects caused by Tresiba, you should talk to your doctor, and they will help you prevent and manage them. Adverse Side Effects of Tresiba Flextouch 200 Units/ml may include: 

• Severe hypoglycemia: This occurs when blood sugar levels drop dangerously low, which can lead to symptoms like confusion, seizures, loss of consciousness, or even death if not treated promptly. It’s crucial for users to monitor their blood sugar levels regularly and be aware of early signs like shakiness or sweating.
• Weight gain: Like other insulin therapies, Tresiba can cause an increase in body weight. This is due to the way insulin promotes the storage of fat and glucose in the body, making it important for patients to manage their diet and activity levels.
• Severe allergic reaction: Some individuals may experience an adverse allergic reaction to Tresiba. Symptoms can include hives, swelling, difficulty breathing, and a rapid heartbeat. This can be fatal and requires prompt medical attention.
• Lipodystrophy: Repeated injections in the same injection site can cause changes in the fat distribution under the skin, leading to lumpy or scarred areas. This condition can interfere with insulin absorption and requires rotating injection sites each time you administer the dose.
• Pruritus: Some users might develop itching at the injection site or over a wider area of the skin. This side effect can vary from mild to bothersome, and in some cases, it may indicate an allergic reaction.
• Edema: Swelling because of fluid retention, specifically in the feet/ankles/legs may occur while using Tresiba This can sometimes be linked to changes in how the body handles sodium and water retention during insulin therapy.
• Hypokalemia: Tresiba can lower potassium levels in the blood, leading to hypokalemia. Symptoms include muscle weakness, fatigue, and an irregular heartbeat. Low potassium levels can be dangerous and require monitoring and possible supplementation.

[Note: Remember, this list may not cover all possible side effects. Always consult with your healthcare giver for medical advice about side effects.]

There are certain warnings that you should consider while using Tresiba Flextouch 200 Units/ml to manage your blood sugar levels. Some of the warnings are as follows:

• Do not consume alcohol while using Tresiba Flextouch, as it may decrease or increase your blood sugar levels. You should also avoid using beverages and medications that may contain alcohol. 
• Do not reuse or share your Tresiba Flextouch needle with other people, even if the needle is changed, as a severe infection may spread from one person to another.
• Let your doctor know if you have an allergy to Tresiba, insulin degludec, or any of the inactive ingredients.
• Do not use the medication during episodes of hypoglycemia.
• Look out for symptoms of heart failure. If heart failure occurs, you may need dosage adjustments or discontinuation of the medication. 
• While receiving treatment with Tresiba, you should look out for signs and symptoms of hypokalemia, a life-threatening condition that is caused due to high levels of potassium in the body. This can further cause coma and even death if not treated promptly.

What Are the FDA Boxed Warning for Tresiba Flextouch 200 Units/ml?

A boxed warning for Tresiba Flextouch 200 unit ml has been issued by the FDA due to the potential risks of thyroid C-cell tumors associated with its use. Some key points of the black box warning are shared below.

• Tresiba can cause dose-dependent and treatment-duration-dependent thyroid C-cell tumors in rodents.
• Patients should be advised of this risk and monitored for symptoms of thyroid tumors.

There are certain precautions you should take into consideration before you use Tresiba Flextouch 200 Units/ml to treat diabetes mellitus type 1 or 2. You should tell your doctor about all the medications you are using or plan to use alongside insulin degludec to manage drug interactions. You should also share your complete medical history with your doctor. This information will help them determine if Tresiba Flextouch 200 unit ml insulin pen is suitable for use in your condition.

• Before you use this medication, tell your doctor if you have or ever had kidney problems, liver issues, or no awareness of low blood sugar levels.
• This medication can increase the risk of heart failure in patients, especially if they are using Tresiba with other diabetes medications. Call your doctor immediately if you experience any of the given symptoms of heart failure, such as swelling in your ankles, legs, or feet, shortness of breath, fatigue, or unusual rapid weight gain.
• Insulin degludec may cause dizziness or temporary blurred vision in some people using it. Do not use heavy machinery, drive, or indulge in activities that require alertness unless you know how Tresiba affects you. 
• Tresiba should be used with caution in patients who have liver or kidney disease.
• If you are going to have surgery, including dental surgery, let your doctor or dentist know about all the medications you are taking.
• Before using the medication, tell your doctor if you think you are pregnant, planning to get pregnant, or breastfeeding. Dosage adjustments and changes in medication may be required.

• To get the most benefit from your medication, it is crucial to take your insulin on time and maintain consistency in dosage.
• If you missed a dose of Tresiba, you should take it as soon as you remember.
• However, if it is almost time for your next dose of insulin degludec, you may skip the missed dosage and continue your regular dosage schedule.
• Ensure that there is a gap of 8 hours between your doses.
• Do not simultaneously take two doses of the same medication to compensate for the missed dose.
• You can set a reminder on your phone to prevent missing doses further. Medication reminders work best for this purpose.

[Note: If you have missed a dose of your medication and are unsure about when to take the next one, immediately consult your doctor or pharmacist.]

If someone you know has overdosed on insulin degludec, is having trouble breathing, has passed out, or can’t be woken, immediately call 911. You may also head to the nearest emergency room. Symptoms of an overdose include rapid heartbeat, shakiness, excessive sweating, and loss of consciousness.

[Note: If you consumed more than the recommended dose, get medical help right away or call the Poison Help line at 1-800-222-1222.]

• You may store unopened Tresiba FlexTouch in the refrigerator. But do not freeze it. Do not use this product if it is frozen. Using cold insulin may be painful. Discard it safely and get a new one from your pharmacist.
• While you are using the Tresiba FlexTouch, it should be kept in the original container at average room temperature, away from direct sunlight, excess heat, and moisture.
• Do not store Tresiba with the needle attached. Do not reuse or share your needles; safely discard them in a sharps container. If you don’t have a sharps container, use a container of hard plastic with a tightly fitting lid.
• Keep the insulin away from the sight and reach of children.
• Do not flush down any medication or throw it in wastewater unless instructed by your health provider.
• Throw away the Tresiba Flextouch after 56 days, even if there is insulin left in it. Also, throw away the insulin that is no longer needed or outdated safely.
• You should dispose of medications that are outdated or no longer needed in such a way that prevents children, animals, and other people from consuming them.
• You should discard used needles, syringes, and pre-filled pens in an FDA-approved sharps container. If you do not have a sharps container, you can use a container made of hard plastic with a tightly fitting lid.
• The best way to eliminate unwanted medications is to give them in a medicine take-back program.
• If you have doubts or questions regarding the proper disposal of the insulin, contact your pharmacist or local waste disposal company for guidance.

[Note: Discuss with your healthcare professional about the proper disposal of any unused medicine and any questions you may have regarding its storage.]

Certain medications may interact with Tresiba Flextouch 200 Units/ml and reduce its effectiveness or cause unwanted side effects in some people using it. Before you use Tresiba, you should tell your doctor about all the medications you are using or plan to use alongside Tresiba, including all prescription, non-prescription medications, over-the-counter drugs, or herbal and vitamin supplements. This information helps you and your doctor identify and manage drug interactions. Some of the potential drug interactions of Tresiba Flextouch 200 unit ml are as follows:

• Monoamine oxidase inhibitors: These medications can increase the hypoglycemic effect of insulin by altering glucose metabolism, thus requiring close monitoring. 
• SGLT-2 inhibitors: These medications work by removing excess glucose through the urine. When used with insulin, monitoring for signs of low blood sugar and dehydration is necessary.
• GLP-1 receptor agonists: These drugs enhance insulin secretion and may lead to an additive effect when combined with insulin, increasing the risk of hypoglycemia.
• DPP-4 inhibitors: Also aim to increase insulin production and decrease glucose production in the liver, requiring careful blood sugar monitoring to avoid hypoglycemia.
• ACE inhibitors: These are primarily used for hypertension and can increase the blood-glucose-lowering effect of insulin, potentially leading to hypoglycemia. 
• Corticosteroids: These significantly decrease insulin sensitivity, often leading to marked changes in insulin requirements.
• Diuretics, particularly thiazide and loop diuretics, can potentially reduce blood glucose control by inducing hyperglycemia.
• Estrogens and oral contraceptives: They can typically increase blood glucose levels, which might require a higher dose of insulin.
• Thyroid hormones: These can increase blood glucose levels, thereby necessitating adjustments in insulin dosing.
• Beta-blockers: These medications can mask the symptoms of low blood sugar, which is critical for patients on insulin to be aware of.
• Thiazolidinediones (TZDs): While these enhance insulin sensitivity, fluid retention and heart failure are risks when combined with insulin.
• Sulfonylureas and Meglitinides: Both stimulate insulin production from the pancreas, which can intensify the hypoglycemic effect when used with Tresiba.
• Certain antibiotics, such as fluoroquinolones, can alter blood glucose levels by producing hyperglycemic or hypoglycemic conditions.

[Note: This isn’t a complete list, and there could be other drugs that interact with Tresiba Flextouch 200 Units/ml. Make sure to tell your doctor about any prescription, over-the-counter medicines, and herbal products you’re taking.]

What Are the Other Tresiba Flextouch 200 Units/ml Interactions?

Apart from medications, certain herbs, beverages, food items, and supplements can interact with insulin degludec and affect its effectiveness. You should not consume alcohol as it can influence the blood sugar levels and insulin requirements of patients. Products like garlic, fenugreek, and omega-3 fatty acids can affect levels of blood glucose and should be used cautiously. Apart from these interactions, Insulin degludec also has certain disease interactions that you should consider before using Tresiba. Always consult an expert medical practioner before using a medication. Disease interactions of Tresiba Flextouch 200 unit ml insulin pen are as follows:

• Liver disease
• Kidney disease
• Thyroid disorders
• Cushing’s syndrome
• Infection or fever
• Cardiovascular disease
• Gastroparesis
• Adrenal insufficiency

While Tresiba Flextouch 200 Units/ml is an effective medication used to manage diabetes mellitus type 1 or 2, it may not be suitable for everyone, or it may cause undesirable side effects in some people. For these reasons, many people are looking for alternatives to insulin degludec. Various factors influence the choice of alternatives to Tresiba, such as individual patient responses, side effects, cost factors, and specific medical needs. You should consult your doctor before changing your prescription or starting a new medication. There are many effective medications available in the market. Some of the most popular alternatives to Tresiba Flextouch 200 Units/ml are as follows:

• Lantus (insulin glargine)
• Basaglar (insulin glargine)
• Toujeo (insulin glargine)
• Levemir (insulin detemir)
• Xultophy (liraglutide)

[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.]

The cost of Tresiba Flextouch 200 Units/ml and options for obtaining it at affordable prices can be significantly influenced by the individual health insurance policies. Many people find that their insurance does not fully cover this long-acting insulin, leading to substantial out-of-pocket expenses. To reduce this financial burden, many individuals turn to alternative purchasing options, such as Polar Bear Meds, which offers the opportunity to buy Tresiba Flextouch online from Canada at more competitive rates. Additionally, customers can benefit from using the Tresiba Flextouch coupon code WELCOMEPB10 at checkout, securing a 10% discount on their first order, thus enhancing affordability and accessibility for those managing diabetes.

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