
Milbemycin Oxim…


We offer competitive pricing on all our medications. Find a lower price? We'll match it from any verified Canadian online pharmacy! Know More

We offer competitive pricing on all our medications. Find a lower price? We'll match it from any verified Canadian online pharmacy! Know More
Ordering your medication online is simple and convenient.
Select the prescribed dosage and quantity, then proceed to checkout.
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Upload your prescription.
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Select the prescribed dosage and quantity, then proceed to checkout.
Sign in or create a new account.
Upload your prescription.
Complete your purchase by processing the payment.
Shipping takes approximately 3-5 business days.
Read what our customers have to say about their shopping experience.
Trifexis is a prescription-only medication that is specifically formulated for dogs. These chewable tablets combine two active ingredients, spinosad and milbemycin oxime, to provide complete protection against parasites. This dual-action medication is used for various conditions. It primarily kills adult fleas within 30 minutes of administration, prevents heartworm disease, flea infestations, and treats and controls hookworm, roundworm, and whipworm infections. Trifexis is suitable for dogs & puppies at least 8 weeks of age and weighing at least 5 pounds. It is administered orally once a month and provides continuous protection against parasites. To order Trifexis online for your dog, ensure you obtain a valid prescription from a certified veterinarian.
| Generic Name | Spinosad and Milbemycin Oxime |
| Brand Name | Trifexis |
| Forms | Chewable Tablet |
| Strengths Available | 140 mg/2.3 mg & 270 mg/4.5 mg & 560 mg/9.3 mg & 810mg/13.5mg &1620 mg/27 mg |
| Packaging | - |
| Requires Prescription | Prescription only (Rx) |
| Ships to USA | Yes |
Trifexis is used to:
The recommended dose for Trifexis may differ based on the dog’s weight. If you are planning to buy Trifexis online for your dogs, refer to the dosing schedule below:
Administering Trifexis to your dog is a simple process. Here are some important tips on how to use Trifexis that pet owners should consider:
Trifexis is a combination of two drugs that help protect dogs from multiple parasites. Its first active component, spinosad, targets fleas by disrupting their nervous system. It kills fleas within 30 minutes and eliminates most within 4 hours. The other active component, milbemycin oxime, interferes with the nerve transmission in heartworms and intestinal parasites. This dual-action formula circulates the dog’s bloodstream for a month, offering continuous protection.
Common Trifexis side effects may include:
Serious Trifexis side effects may include:
Note: Contact your healthcare provider if you experience any serious symptoms or unusual changes.
Here are some important warnings that pet owners should consider when they order Trifexis online:
If you are planning to buy Trifexis online for heartworm disease or parasite prevention, be mindful of the following precautions to prevent any potential risks:
If you missed giving a dose of Trifexis to your dog, administer the dose as soon as possible. Moving forward, continue giving the doses according to your regular monthly dosing schedule. In the meantime, observe your dog for any adverse reactions. However, if it’s been more than two weeks since the missed dose, consult a veterinarian. Never administer two doses at once to compensate for the missed dose.
If you have accidentally given an excessive amount of Trifexis to your dog, take immediate action or call the poison control helpline. Some of the common overdose symptoms of Trifexis may include:
At Polar Bear Meds, we’re committed to making prescription medications like Trifexis more accessible and affordable for USA patients. Our prices are significantly lower than typical USA pharmacy retail rates without compromising on safety or quality. Every order is sourced exclusively from licensed and trusted pharmacies and undergoes complete prescription verification to ensure compliance and authenticity. We offer discreet, trackable shipping to all USA states, along with refill support for ongoing treatment. Our friendly customer service team is here to help you.
Buy Trifexis from Canada and get it delivered straight to your doorstep in the USA. You can also save more by using the coupon code “WELCOMEPB10” for 10% off on your first order. There are no hidden handling or processing fees, as we believe in complete transparency. Looking to save even more? Join our referral program and get a $20 credit every time you refer a friend or a family member. Your referral will also receive a $20 credit, so everyone wins. Additionally, after every 10 verified customers' referral, you'll receive a $100 credit in your account as a thank-you for spreading the word.
AtPolar Bear Meds, your safety is our priority. Every order is dispensed from a fully licensed Canadian pharmacy following strict standards for quality, security, and patient care. To conveniently buy Trifexis from Canada at a substantial cost, call us at 1-888-779-2193 toll-free.
The content provided on the Polar Bear Meds website serves to increase knowledge about healthcare products and medical conditions and is strictly for informational purposes. It should not replace professional medical advice. We urge you to consult with a qualified healthcare professional prior to utilizing any prescription or over-the-counter medication. Our platform grants access to an extensive array of products, sourced internationally, including Canada. We collaborates with a licensed pharmacy partner in Canada and trusted dispensing pharmacies globally. All affiliated fulfillment centers are accredited by the regulatory authorities of their respective countries.

Dr. Jackson Miller is a board-certified medicine physician & hospitalist. He is a healthcare professional with a strong background in patient care. With years of experience and a patient-first approach, he believes the foundation of good health is a patient who feels informed and empowered. He contributes to medical content review, drawing on his background in clinical practice and patient education. He focuses on presenting health information in a clear, accurate, and accessible way to help readers make informed decisions. His work emphasizes clarity, evidence-based guidance, and understandable explanations of medical topics.

We offer competitive pricing on all our medications. We'll match if you find a lower price on an identical product at a verified Canadian online pharmacy!
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