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We offer competitive pricing on all our medications. Find a lower price? We'll match it from any verified Canadian online pharmacy! Know More
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Select the prescribed dosage and quantity, then proceed to checkout.
Sign in or create a new account.
Upload your prescription.
Complete your purchase by processing the payment.
Shipping takes approximately 3-5 business days.
Ubrelvy is a prescription oral medication whose active ingredient is ubrogepant. It belongs to the class of drugs called calcitonin gene‑related peptide (CGRP) receptor antagonists. Ubrelvy is FDA‑approved for use in adults for the acute treatment of migraine attacks with or without aura. As a prescription‑only medicine, Ubrelvy should be taken exactly as directed by your provider or doctor to ensure optimal results.
| Aspect | Details |
|---|---|
| Brand Name | Ubrelvy |
| Generic Name | Ubrogepant |
| Drug Class | Calcitonin gene‑related peptide (CGRP) receptor antagonist |
| Status | FDA-approved |
| Indication | Acute treatment of migraine with or without aura in adults |
| Limitations of Use | Ubrelvy is not indicated for the preventive treatment of migraine |
| Dosage Form | Oral tablets |
| Strengths Available | 50 mg, 100 mg |
| Common Side Effects | Nausea, somnolence, dry mouth |
| Contraindications | Hypersensitivity to ubrogepant or any component of the product |
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Ubrelvy works by blocking the activity of the calcitonin gene-related peptide (CGRP) at its receptor, a key protein involved in migraine pain signaling. During a migraine attack, CGRP levels rise and contribute to headache pain, light and sound sensitivity, and other migraine symptoms. By inhibiting CGRP, Ubrelvy helps reduce migraine pain and associated symptoms when taken at the onset of an attack.
Here are general administration guidelines on how to take Ubrelvy for migraine attack treatment:
This is not a complete list of Ubrelvy side effects. If you notice other adverse reactions, tell your doctor right away.
Ubrelvy dosage should always be determined and supervised by a healthcare provider. The following are general dosage guidelines for adults treating acute migraine attacks:
| Aspect | Guidance |
|---|---|
| Recommended Dose | 50 mg or 100 mg taken orally at the onset of a migraine attack |
| Repeat Dose | A second dose may be taken at least 2 hours after the first, if needed |
| Maximum Dose | Do not exceed 200 mg in a 24-hour period |
| Special Populations | For severe hepatic impairment or severe renal impairment (CrCl 15–29 mL/min), the recommended dose is 50 mg; a second 50 mg dose may be taken after 2 hours if needed. |
| Frequency of Use | The safety of treating more than 8 migraine attacks in 30 days has not been established |
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Important Ubrelvy (ubrogepant) precautions and potential risks include:
Ubrelvy (ubrogepant) interacts with certain medications. Some of the Ubrelvy interactions include:
| Drug Category / Class | Examples | FDA Guidance |
|---|---|---|
| Strong CYP3A4 Inhibitors | Ketoconazole, Itraconazole, Clarithromycin | Contraindicated, may significantly increase ubrogepant levels and risk of side effects |
| Strong CYP3A4 Inducers | Rifampin, Phenytoin, Carbamazepine, St. John’s Wort | Avoid, may reduce ubrogepant effectiveness by lowering drug levels |
| Moderate CYP3A4 Inhibitors | Verapamil, Fluconazole, Diltiazem | Dose adjustment required, consult your healthcare provider |
| Other CGRP Antagonists | Nurtec ODT (rimegepant), Qulipta (atogepant) | Use caution. Concomitant use with other CGRP antagonists has not been extensively studied. |
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This list is not exhaustive. Always check with your provider or pharmacist before taking Ubrelvy with any new medication, including OTC drugs and herbal supplements.
If Ubrelvy is not suitable or causes side effects, your healthcare provider may consider other medications for the acute treatment of migraine. The choice of alternative depends on your health profile, migraine severity, and response to previous therapies.
Many patients choose to buy Ubrelvy from Canada because it is often more affordable than U.S. retail pricing while maintaining high quality and safety standards. At Polar Bear Meds, we partner with a network of licensed Canadian and international pharmacies that operate under regulated dispensing practices to help ensure medication authenticity and proper handling.
By ordering Ubrelvy online through our pharmacy, patients may benefit from significant cost savings compared to typical U.S. pharmacy prices, along with reliable delivery and customer support.
A valid prescription from a licensed healthcare provider is required to purchase Ubrelvy from Canada. Polar Bear Meds also offers additional savings options, including:
The information provided about Ubrelvy is for educational purposes only & does not replace professional medical advice, diagnosis, or treatment. Ubrelvy is a prescription medication and should be used only under the guidance of a licensed healthcare provider. Always consult your healthcare professional before stopping, starting, or changing any medication.
Learn more about Ubrelvy and related topics

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