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Are Tresiba and Lantus the Same: How These Insulin Drugs Compare in Dosage and Use

HOME | DIABETES EDUCATION | ARE TRESIBA AND LANTUS THE SAME: HOW THE INSULIN DRUGS COMPARE

As you manage diabetes, understanding the differences between Tresiba and Lantus is essential for your treatment plan. Both insulins may seem similar at a glance, but their dosage and usage can greatly impact your blood sugar control.

Tresiba offers flexibility with its longer duration, while Lantus has a more structured timeline. This distinction raises important questions about convenience, effectiveness, and how these variations may affect your daily routine.

So, how do you know which one might be more suitable for you? Let’s examine the nuances that could make all the difference.

Key Takeaways

  • Tresiba (insulin degludec) lasts up to 42 hours, while Lantus (insulin glargine) lasts about 24 hours, indicating different dosing frequencies.
  • Both insulins are typically dosed once daily, but timing consistency is crucial for Lantus due to its pronounced peak effects.
  • Starting doses for both medications usually begin at 10 units, but adjustments are essential when switching between them to avoid hypoglycemia.
  • Tresiba may provide better glycemic control and lower hypoglycemia risk (10-12%) compared to Lantus (6-10%).
  • Storage requirements differ; opened Tresiba can last 8 weeks at room temperature, while opened Lantus lasts 28 days, affecting usage duration.

Are Tresiba and Lantus the Same Insulin?

Upon managing diabetes, you might wonder if Tresiba and Lantus are the same insulin. Although both are long-acting insulin medications, they differ greatly. Tresiba contains insulin degludec, which offers an ultra-long duration of action lasting up to 42 hours. This extended time allows for flexible dosage schedules and may lower the risk of hypoglycemia.

In contrast, Lantus contains insulin glargine and typically lasts around 24 hours. Both Tresiba and Lantus are available in vials and prefilled pens, but Tresiba comes in strengths of U-100 and U-200, while Lantus is available only as U-100. The more concentrated U-200 formulation of Tresiba can be beneficial for patients needing higher doses.

Additionally, Tresiba starts to work within 60 minutes and provides a steady insulin release with no pronounced peak. Lantus begins within 70 minutes and takes up to 6 hours to achieve its full blood sugar-lowering effects.

Ultimately, while Tresiba and Lantus serve similar purposes in managing blood sugar levels, their differences may affect your treatment choices. Always discuss with your healthcare provider which is best for your Effective diabetes management often involves understanding how Tresiba or Lantus may work for individual patients..

Main Differences Between Tresiba and Lantus Insulin

Tresiba and Lantus, while both serving in the capacity of long-acting insulin options for diabetes management, present notable differences that can impact your treatment plan. Understanding these contrasts is essential for effective blood sugar control.

  • Active Ingredients: Tresiba contains insulin degludec, while Lantus contains insulin glargine, and both are given by subcutaneous injection.
  • Duration: Tresiba lasts up to 42 hours, offering greater flexibility in dosing, compared to Lantus, which lasts about 24 hours.
  • Onset and Peak: Tresiba begins working in 60 minutes without a significant peak, whereas Lantus starts within 70 minutes and has a gradual effect.
  • Dosing Forms: Tresiba is available in U-100 and U-200 strengths, allowing higher doses if needed. Lantus is solely U-100.
  • Hypoglycemia Risk: Research suggests Tresiba may lower the risk of hypoglycemia compared to Lantus, which can be particularly important if you’re prone to low blood sugar episodes.

These key differences should help you and your healthcare provider decide which insulin aligns best with your individual needs, helping to effectively manage your blood sugar levels.

Tresiba vs. Lantus: Dosage Comparison and Differences

While considering insulin options for diabetes management, understanding the dosage differences between Tresiba and Lantus is essential. Tresiba, containing insulin degludec, offers an ultra-long duration of action lasting up to 42 hours. This allows for flexible dosing times and may help achieve better blood sugar control. The recommended starting dose for Tresiba in type 1 diabetes is about one-third to one-half of the total daily insulin requirement, while for type 2 diabetes, it starts at 10 units daily.

In contrast, Lantus contains insulin glargine and typically lasts around 24 hours. Its starting dose is usually 10 units for both type 1 and type 2 diabetes.

Both insulins lack a significant peak in action, but Lantus can take up to 6 hours to reach full effectiveness.

When switching between Tresiba and Lantus, be cautious about adjusting dosages to reduce hypoglycemia risk, since Tresiba may present a lower risk than Lantus overall.

Both long-acting insulins Using Tresiba or Lantus may effectively manage diabetes, but the specific characteristics and starting doses can help you and your healthcare provider determine which one suits you best.

Which Lasts Longer: Tresiba or Lantus Insulin?

Choosing between Tresiba and Lantus can hinge on their differences in duration of action, so it’s important to talk with your doctor. Understanding how long each insulin lasts helps you manage your diabetes more effectively.

  • Tresiba (insulin degludec) offers an ultra-long duration of action, lasting up to 42 hours.
  • Lantus (insulin glargine), a long-acting insulin, typically lasts around 24 hours but may extend up to 36 hours in some individuals.
  • The extended action of Tresiba allows for more flexible dosing times, which can be a significant advantage for daily routines.
  • Fewer injections can be a result of Tresiba’s longer action.
  • Tresiba may help reduce the risk of hypoglycemia due to its stable release.

Tresiba works longer in the body compared to Lantus, with effects lasting up to 42 hours. Lantus works for about 24 hours. Tresiba may also have a lower risk of hypoglycemia (low blood glucose) than Lantus.

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Is Tresiba More Effective Than Lantus Insulin?

While managing diabeteseffectiveness often weighs heavily in your choice of insulin. As comparing Tresiba (insulin degludec) and Lantus (insulin glargine), both are effective long-acting insulins for controlling blood sugar levels. Clinical studies suggest that Tresiba may achieve a larger decrease in blood sugar levels compared to Lantus. However, both insulins provide similar long-term glycemic control, as reflected in hemoglobin A1C tests.

One significant advantage of Tresiba is its reduced hypoglycemia risk. Patients who are prone to low blood sugar episodes may find Tresiba safer due to its more stable insulin release without pronounced peaks. This characteristic can be particularly beneficial for managing daily routines and unpredictable activities.

Dosage of Tresiba offers flexibility as well, allowing for administration at different times without compromising effectiveness.

Considering these factors, some patients might prefer Tresiba over Lantus for its longer duration of action and lower hypoglycemia risk. Ultimately, it’s important to discuss with your healthcare provider which insulin suits your specific needs best. Both Tresiba and Lantus have unique strengths that cater to different lifestyles and preferences.

Tresiba vs. Lantus: Side Effects Compared

Each time managing diabetes with insulin, understanding the side effects of Tresiba and Lantus is vital for making an informed choice.

Both medications are long-acting insulin, but they’ve different profiles regarding side effects.

Here are some common side effects you might experience with either insulin:

  • Hypoglycemia (low blood sugar):
  • Tresiba: 10-12% of users may experience this.
  • Lantus: 6-10% of users report this.
  • Weight Gain: Both insulins can contribute to weight gain.
  • Injection Site Reactions: Redness, swelling, or itching may occur at the injection site.
  • Allergic Reactions: Mild allergic reactions can happen, although severe ones are rare.
  • Other Mild Side Effects: Headaches, upper respiratory infections, and changes in skin thickness.

While Tresiba (insulin degludec) may carry a slightly higher risk of hypoglycemia than Lantus (insulin glargine), both can lead to serious concerns such as severe hypoglycemia and hypokalemia.

It’s important to discuss these potential side effects with your healthcare provider to determine which insulin is best for you.

Can Tresiba and Lantus Be Used Interchangeably?

Knowing the differences in side effects between Tresiba and Lantus is important for understanding their interchangeability. While both are long-acting insulins, they’re not interchangeable without guidance from a healthcare provider. Tresiba lasts up to 42 hours and offers flexible dosing, whereas Lantus typically lasts about 24 to 36 hours.

If you’re considering switching from one insulin to the other, it’s vital to consult your healthcare provider. They’ll assess your current insulin regimen, blood sugar levels, and overall health to determine the appropriate dosage.

The different active ingredients—insulin degludec in Tresiba and insulin glargine in Lantus—mean that the pharmacokinetics of these insulins vary greatly, affecting how well they work for you.

Your healthcare provider will guide you on the best practices for switching, ensuring that you maintain ideal blood sugar control throughout the process.

Cost Comparison of Tresiba vs. Lantus Insulin

Understanding the cost differences between Tresiba and Lantus can greatly influence your treatment choices when managing diabetes.

As you evaluate these insulins, consider several factors:

  • Tresiba’s price for a 10 mL vial is around $363.36.
  • 3 mL FlexTouch pen of Tresiba can cost about $400, but discounts may lower it to $350.
  • Lantus, on the other hand, has a 10 mL vial priced at approximately $305.53 is the price for a box of Tresiba Flextouch, which may be covered by insurance..
  • The 3 mL Solostar pen for Lantus typically averages $100, with discounts possibly bringing that down to as low as $70.

Insurance coverage varies for both insulins, so always check your specific plan for details.

As you decide between these insulins, carefully consider your dosage requirements and potential discounts.

Overall, Tresiba tends to be more expensive than Lantus, which could affect your choice based on out-of-pocket costs and insurance coverage.

Consulting your healthcare provider can help clarify which option might be best for your financial and medical situation.

Is Tresiba Safer Than Lantus for Long-Term?

Considering the differences in hypoglycemia risk and overall safety profiles, the question of whether Tresiba is safer than Lantus for long-term use arises. Tresiba, or insulin degludec, has a lower risk of hypoglycemia compared to Lantus, which is insulin glargine. Clinical studies highlight that patients using Tresiba experience fewer low blood sugar events, making it potentially a safer option for individuals at risk of hypoglycemia.

While both long-acting insulins manage blood sugar effectively, Tresiba may offer slight benefits in glycemic control in certain cases. Its extended duration of action, lasting up to 42 hours, allows for more flexible dosing, which can improve adherence to treatment. In contrast, Lantus generally has a 24-hour duration, requiring more stringent timing for administration.

Given the implications of hypoglycemia, especially for those with a history of these episodes, Tresiba’s safety profile may make it a better choice for long-term use.

However, every individual’s response to insulin can vary markedly. Consulting with a healthcare provider is essential to determine the most suitable insulin therapy tailored to your specific needs and medical history.

Better Insulin for Type 1: Tresiba vs. Lantus


While managing type 1 diabetes, choosing the right insulin can considerably impact your overall treatment success.

Comparing Tresiba and Lantus reveals important differences that may affect your daily routine, blood sugar control, and the type of insulin you choose.

  • Duration: Tresiba lasts up to 42 hours, while Lantus, or insulin glargine, typically lasts about 24 hours.
  • Hypoglycemia Risk: Tresiba has a lower risk of causing hypoglycemia, making it safer for those prone to low blood sugar.
  • Dosage Flexibility: With Tresiba, you have more flexibility in dosing times thanks to its longer action.
  • Administration: Both insulins are administered once daily, but Tresiba’s stable release helps maintain consistent blood sugar levels.
  • Child Approval: Tresiba is approved for children aged 1 year and older, while Lantus is for children aged 6 years and older.

Ultimately, both Tresiba and Lantus are effective long-acting insulins for managing blood sugar levels.

However, Tresiba might be considered a better option for some individuals.

It’s essential to discuss your specific needs and preferences with your healthcare provider to determine the best choice for you.

Injection Times: Differences Between Tresiba and Lantus

While managing diabetes, understanding the injection times and pharmacokinetics A pharmacist can provide guidance on the duration of Tresiba or Lantus to help maintain blood sugar levels and manage any potential drug interactions. Both insulin types serve as long-acting options, but they differ greatly in their timing and effectiveness.

Tresiba, which contains insulin degludec, starts working within 60 minutes after injection and has a unique peak action around 12 hours post-injection. Its long duration of up to 42 hours offers you the flexibility to inject at different times, although consistency is recommended, especially in children.

On the other hand, Lantus, made with insulin glargine, begins to act within 70 minutes. Unlike Tresiba, it doesn’t display a pronounced peak, but its full blood sugar-lowering effect can take up to 6 hours. Lantus typically lasts about 24 to 36 hours, meaning you’ll need to inject it at the same time each day for best effectiveness.

Choosing the right insulin and understanding these timing differences between Tresiba and Lantus will help you manage your diabetes more effectively, ensuring you achieve stable blood sugar levels.

Always consult with your healthcare provider for personalized advice.

Storage Requirements for Tresiba vs. Lantus Insulin

Understanding the storage requirements for Tresiba and Lantus insulin is critical for maintaining their effectiveness. Proper handling can notably affect how well the insulin manages your blood sugar levels.

Here’s what you need to know about storage:

  • Unopened Storage: Both Tresiba and Lantus should be kept in the refrigerator between 36°F and 46°F (2°C to 8°C).
  • Opened Storage for Tresiba: After opening, you can store Tresiba at room temperature (up to 86°F or 30°C) for up to 8 weeks.
  • Opened Storage for Lantus: Once opened, Lantus can be kept at room temperature (up to 77°F or 25°C) for up to 28 days.
  • Freezing: Neither Tresiba nor Lantus should ever be frozen, since this can damage the insulin.
  • Original Carton: Always store both insulins in their original carton to protect them from light.

Knowing these storage guidelines helps maintain your insulin’s potency and effectiveness, which is crucial for proper dosage management.

Always check with your healthcare provider if you’re unsure about storage practices.

Switching from Lantus to Tresiba: How Easy?

If you’re considering switching from Lantus to Tresiba, it’s important to approach the change with care.

Start by consulting your doctor, since they’ll evaluate your specific needs and determine if the switch is right for you. At the time of moving from insulin glargine (Lantus) to insulin degludec (Tresiba), your doctor will likely recommend a dosage adjustment. While your Tresiba dosage may be similar to what you were using with Lantus, individual needs can vary.

Be aware that changing insulins may lead to blood sugar fluctuations. Close monitoring of your blood glucose levels during this shift is essential to detect any potential hypoglycemia or hyperglycemia quickly.

Furthermore, verify you’re using the proper injection technique to minimize the risk of reactions at the injection site.

After switching, your healthcare provider may want to keep a close eye on your progress, making further adjustments as needed.

Blood Sugar Control: Tresiba vs. Lantus Comparison

Effectively managing blood sugar levels is essential for anyone with diabetes, and choosing the right insulin can make a significant difference.

At the time of comparing Tresiba (insulin degludec) and Lantus (insulin glargine), consider the following key points:

  • Glycemic Control: Both Tresiba and Lantus are effective in managing blood sugar levels.
  • Duration of Action: Tresiba lasts up to 42 hours, while Lantus lasts about 24 hours.
  • Dosing Flexibility: Tresiba allows for varying administration times, which is advantageous for busy lifestyles.
  • Hypoglycemia Risk: Tresiba has a lower risk of hypoglycemia, making it safer for those prone to low blood sugar episodes.
  • Overall Efficacy: Clinical studies show Tresiba can lead to greater decreases in blood sugar levels.

While both insulin options can help maintain target blood sugar levels, your choice may depend on lifestyle and specific medical needs.

Tresiba’s longer duration might appeal to some, while others may prefer Lantus for its established use.

Always consult with your healthcare provider to determine which insulin therapy suits your personal requirements best.

Frequently Asked Questions

Can You Mix Tresiba or Lantus With Other Insulins?

Don’t mix Tresiba or Lantus with other insulins unless your doctor says it’s okay. Mixing can change how well they work and might raise the chance of low blood sugar, particularly for people with type 1 or type 2 diabetes. Always ask your doctor for advice that fits your needs.

What Should You Do if You Miss a Dose of Tresiba or Lantus?

If you miss a dose of Tresiba or Lantus, take it when you remember unless it’s almost time for your next dose. Don’t take two doses at once. Just go back to your regular schedule after that.

Are Tresiba and Lantus Safe During Pregnancy?

Talk to your doctor if you’re pregnant and thinking about Tresiba or Lantus. They will check your health and help you pick the safest medicine for your diabetes during pregnancy.

How Do Tresiba and Lantus Affect Weight Management?

Tresiba, Lantus, appetite, metabolism, weight gain, weight fluctuations.

Can Tresiba or Lantus Cause Allergic Reactions?

Yes, Tresiba and Lantus can cause allergic reactions, but it’s not common. You might see symptoms like itching, rash, or swelling, which could indicate serious side effects. If you notice anything weird after using these insulins, talk to your doctor.

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