Fluticasone Propionate and Salmeterol Xinafoate
Seretide Accuhaler
Seretide is a combination accuhaler containing two medications: fluticasone propionate, a corticosteroid, and salmeterol xinafoate, a long-acting beta2-agonist. These active ingredients are used to treat asthma and COPD (chronic obstructive pulmonary disease). Seretide accuhaler is an innovative and user-friendly device that improves breathing and prevents symptoms associated with asthma and COPD, including wheezing and breath shortness. This product can be used by adults and children, but each group has different dosage recommendations. Since Seretide accuhaler is a prescription medication, it should not be shared with other individuals, even if they have asthma or COPD. Doing so may cause serious allergic reactions, which can be fatal. Therefore, always follow your doctor’s advice before starting your treatment with Seretide accuhaler.
Product Overview
The Seretide accuhaler is a prescription medication designed to provide relief for patients with asthma and chronic obstructive pulmonary disease (COPD). This innovative inhaler combines two active ingredients, including fluticasone propionate, a corticosteroid that lowers inflammation in the airways, and salmeterol xinafoate, a long-acting beta2-agonist that helps lossens the muscles around the airways. Together, these components work to improve breathing and prevent symptoms like wheezing & shortness of breath. The Seretide accuhaler is FDA-approved and widely recommended by healthcare professionals.
This accuhaler has several strengths, including 50/100 mcg, 50/250 mcg, and 50/500 mcg of fluticasone/salmeterol. It comes in a user-friendly, dry powder inhaler form that delivers a consistent dose each time. To use, simply open the Accuhaler, exhale fully, keep the mouthpiece in your mouth & inhale deeply. It is suitable for adults and children over four years old. This combination medication works by lowering inflammation and expanding the airways, making it easier to breathe and reducing the frequency of asthma attacks and COPD exacerbations.
Common side effects of Seretide may include throat irritation, headache & hoarseness. It is important to rinse your mouth after each use to prevent oral thrush. Use the medication as prescribed by your medical provider. If you miss a dose, take it as soon as you remember, but skip it if it is almost time for your next dose. In case of an overdose, get medical attention immediately. Store the Seretide accuhaler in a cool, dry place away from moisture & direct sunlight to maintain its efficacy. Always keep it out of reach of children.
What Are the Uses of Seretide Accuhaler?
It is used for:
- Asthma: Seretide is prescribed for the regular treatment of asthma, also known as reversible obstructive airway disease. It can be used in adults, teenagers, and children 4 years of age and above. It is important to note that this medication is not suitable for the initial management of asthma unless the symptoms are uncontrolled.
- Chronic Obstructive Pulmonary Disease (COPD): Seretide is also used to treat moderate to severe COPD in adults who have symptoms after bronchodilator therapy.
What Are the Forms & Strengths of Seretide Accuhaler?
It is available in the form of a dry inhalation powder with the following strengths:
Seretide accuhaler
- 100/50 (100 mcg of fluticasone propionate and 50 mcg of salmeterol)
- 250/50 (250 mcg of fluticasone propionate and 50 mcg of salmeterol)
- 500/50 (500 mcg of fluticasone propionate and 50 mcg of salmeterol)
What Is the recommended dosage for Seretide Accuhaler?
The dosage recommendations for Seretide accuhaler depend on several factors, including the type and severity of your medical condition and the form of medication you take. Generally, medical professionals prescribe a starting dose and gradually adjust the drug doses as needed. It is important to note that the dosage recommendations below are only for the average dose. So, if you have been prescribed a different dose, do not change it without consulting your medical practitioner.
Dosage for Asthma
- For Adults & Adolescents (12 Years and Older): One inhalation of 50mcg salmeterol & 100mcg fluticasone propionate twice daily. You can also take one inhalation of 50mcg of salmeterol & 250mcg of fluticasone propionate.
- For Children 4 Years of Age and Above: Take one inhalation of 50mcg of salmeterol & 100mcg of fluticasone propionate two times a day.
- For Children Under 4 Years of Age: Medical professionals have not yet determined the safety and effectiveness of the medication.
Dosage for COPD
- For Adults: Take one inhalation of 50mcg salmeterol and 250mcg fluticasone propionate two times a day.
[Note: Remember, these recommendations may vary from person to person. Discuss it with your doctor, and they’ll customize your dosage accordingly.]
How to Use Seretide Accuhaler?
- Read the medication guide or PIL (patient information leaflet) thoroughly to know the detailed administration steps. If you have any queries, you can ask a healthcare professional to avoid any adverse complications.
- Follow the dosage recommendations exactly as they are mentioned on your prescription label.
- Seretide accuhaler is only for inhalation purposes. The medication should be inhaled directly into the lungs.
- Before using the accuhaler, you need to prepare the device. Hold the Accuhaler in one hand.
- Use the thumb of the other hand to slide the thumb grip until you hear a click. This action opens a small hole in the mouthpiece and readies a dose.
- Now, exhale completely and avoid breathing out into the accuhaler.
- Put the mouthpiece to your lips, making sure your lips form a tight seal around it.
- Inhale deeply and try to take the medication in one inhalation.
- Ensure you are inhaling the medication directly into your lungs.
- Once you are done, remove the accuhaler and hold your breath for 10 seconds. This step ensures that the medication settles into your lungs properly.
- Now, release the breath slowly.
- Slide the thumb grip back to the original position to close the device.
- This action resets the accuhaler for the next dose and protects the mouthpiece.
- Rinse your mouth with water & spit it out. This aids in minimizing the risk of developing a fungal infection in your mouth.
[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They’ll adjust it as needed over time.]
How Does Seretide Accuhaler Work?
The Seretide Accuhaler works by combining two active ingredients: fluticasone propionate and salmeterol xinafoate. Fluticasone propionate is a potent corticosteroid that lowers inflammation in the airways, while salmeterol xinafoate is a long-acting beta2-agonist that eases the tensed muscles around the airways. Together, these ingredients help to open up the airways, making it easier to breathe. This dual-action approach helps prevent and control symptoms of asthma & chronic obstructive pulmonary disease (COPD), such as wheezing and shortness of breath. The Seretide Accuhaler delivers a consistent dose of medication, ensuring effective management of these conditions.
Important Safety Information for Using Seretide Accuhaler
What Are the Side Effects of Seretide Accuhaler?
Common Side Effects of Seretide Accuhaler: Like every medication, Seretide can have different side effects. The below reactions may be temporary, lasting from a few days to weeks. However, if they persist for a long period of time and get intense, reach out to your healthcare provider right away. Common side effects of Seretide Accuhaler may include:
- Sinus inflammation
- Stomach discomfort
- Upper respiratory tract infection
- Cough
- Voice change
- Headache
- Aggressive behavior
- Mouth dryness
- Nasopharyngitis
- Fungal infection of the oropharynx
- Anxiety
- Arthralgia
- Back pain
- Blurred vision
- Bronchitis
- Contact dermatitis
- Contusion
- Cough
- Cutaneous reactions
- Dizziness
- Facial edema
- Headache
- Hoarseness
- Hyperactivity in children
- Hypersensitivity reactions
- Sleep disturbances
- Throat irritation
- Tremor
Serious Side Effects of Seretide Accuhaler: Other than the above common reactions, Seretide can cause several adverse effects, which can create life-threatening situations. If you observe any unusual signs that seem concerning, immediately visit the nearest clinic. Serious side effects of Seretide Accuhaler may include:
- Adrenal suppression
- Aggression
- Angioedema
- Atrial fibrillation
- Behavioral disturbances (children)
- Cardiac arrhythmias
- Cushing’s syndrome
- Decrease in bone mineral density
- Depression
- Glaucoma
- Growth retardation (children)
- Hyperglycaemia
- Hypokalaemia
- Paradoxical bronchospasm (on inhalation)
- Pneumonia
- Tachycardia
- Visual disturbances
- Heavy bleeding
- Chest pain
[Note: Remember, this list may not cover all possible side effects. Always consult with your healthcare giver for medical advice about side effects.]
Are There Any Warnings for Seretide Accuhaler?
Seretide accuhaler can cause severe side effects in certain patients, or it may not be an ideal treatment option for specific populations due to their medical conditions. So, if you are using this medication, you should remain cautious. Its warnings are as follows:
- Asthma Patients: Patients with exacerbated and unstable asthma symptoms should not use this accuhaler as Seretide is not for sudden asthma attacks. Always have a fast-acting inhaler (like salbutamol) for quick relief.
- Pneumonia: Studies have reported increased cases of pneumonia in patients with COPD using Seretide. Therefore, COPD patients should be aware of the possible development of pneumonia. Doctors should watch for signs of pneumonia in these patients, as pneumonia and COPD flare-ups can look similar.
- Corticosteroids: Seretide contains inhaled corticosteroids, and such corticosteroid increases the chances of experiencing systemic side effects in patients, which are less likely to happen with oral corticosteroids. The possible side effects may include Cushing’s syndrome, growth retardation, decreased bone density, behavioral changes, adrenal suppression, cataracts, and glaucoma. Patients switching from oral steroids to inhaled fluticasone propionate need special care and regular monitoring of adrenal function. Therefore, patients are advised to consult a medical practitioner before starting treatment with Seretide accuhaler.
- Cardiovascular Diseases: Using sympathomimetic drugs like Seretide can sometimes lead to increased systolic blood pressure and heart rate, particularly at higher doses. In rare cases, Seretide may cause irregular heartbeats such as extrasystoles, atrial fibrillation, and supraventricular tachycardia. Therefore, it is important to use Seretide cautiously in patients with existing heart conditions.
- Lower Serum Potassium: Sympathomimetic drugs can temporarily decrease serum potassium levels. Therefore, Seretide should be administered carefully to patients who are prone to low potassium levels.
- Diabetes Mellitus: While rare, patients have reported increased blood sugar levels while using Seretide. This should be taken into account when prescribing Seretide to patients with a history of diabetes mellitus.
What Are the FDA Boxed Warning for Seretide Accuhaler?
Boxed warnings, also called black-boxed warnings, are among the most stringent guidelines issued by the FDA. These warnings alert doctors and patients about the harmful effects of a particular drug, which can be life-threatening if overlooked. Seretide does not have any boxed warnings, meaning it is safe to use. However, its safety is based on the precautions you take. Therefore, if you are taking this drug, follow the instructions provided by your medical practitioner. If you have any concerns or noticed any unusual symptoms, it’s best to consult with an expert.
What Are the Seretide Accuhaler Precautions?
When considering treatment with Seretide accuhaler, patients should discuss every risk and benefit with their medical practitioner. Here are some of the precautions that you can take before using Seretide accuhaler to treat asthma and COPD:
- Before using this product/medication, patients should tell their healthcare provider if they have allergies or are allergic to any of the medication’s ingredients. The product may contain certain inactive components that can cause severe allergic reactions.
- When considering treatment with Seretide accuhaler, tell your physician about your or your family’s medical history, especially of:
- Adrenal sufficiency
- Cardiac arrhythmias
- Diabetes mellitus
- Electrolyte imbalance
- Long QT syndrome
- Hypertension
- Hyperthyroidism
- Hypokalaemia
- Lactose intolerance
- Severe cardiovascular disorder
- Thyrotoxicosis
- If you are undergoing surgery or any medical procedure, inform your medical expert or surgeon about the products you are using. This includes all prescription drugs, over-the-counter medications, and herbal products.
- If you are using your medication more often, it means your asthma is getting worse. Do not overlook this situation; talk to a medical professional.
- If Seretide accuhaler is not controlling your asthma, consult a doctor. You might need an alternate treatment.
- Seretide can cause serious asthma problems. If your condition does not improve or worsens over time, talk to your medical expert.
- Seretide accuhaler may make you wheeze more right away. If this happens on a regular basis, use a fast-acting inhaler and discontinue Seretide.
- When your asthma symptoms get under control, discuss them with your practitioner. They might gradually reduce your Seretide dose.
- If you have an electrolyte imbalance, correct your electrolyte disorder before starting your treatment with Seretide accuhaler.
- If you have asthma or COPD, avoid stopping the medication abruptly without consulting a medical professional. Doing so may increase the risk of side effects or exacerbate the condition, causing life-threatening situations.
- Patients with active or quiescent pulmonary tuberculosis must use this medication cautiously or under medical supervision.
- If you are pregnant or planning to have a baby, avoid using Seretide accuhaler unless it is clearly needed. While there are limited data, the medication used in this product may harm the unborn baby. Consult a medical professional and discuss every risk and benefit associated with it.
- It is not clear whether this medication is safe during breastfeeding. If you are a nursing mother, talk to your medical expert about the safety of this product for your breastfeeding child.
What Are the Contraindications of Seretide Accuhaler?
Seretide accuhaler is contraindicated in:
- Patients with hypersensitivity reactions to salmeterol xinafoate, fluticasone propionate, or any of the ingredients used in the medication’s formulation. You can check the product’s label or ask a pharmacist for detailed ingredient information.
- Patients with severe milk-protein allergy.
- Children under 4 years of age.
- Patients with QT syndrome
What If You Missed a Dose of Seretide Accuhaler?
Patients are usually advised not to miss their doses of any medication, and when it comes to controlling symptoms of asthma and COPD, taking medication on time becomes more important. However, if somehow you forget to use Seretide accuhaler:
- Take the missed dose as soon as possible unless your doctor advises otherwise.
- Call your doctor for specific instructions on what to do next.
- Remember not to take double doses.
- If it is almost time for the next dose, you may omit the missed dose and continue your regular dosing schedule.
- If you feel chest tightness before taking your dose, use a reliever puffer. You may get relief from it within minutes.
- Use medication apps or set phone reminders to avoid missing doses.
- Take your medication at the same time every day to get the most benefit from it.
- Make sure to get your prescription refilled before you run out of medicine. This will ensure that you do not miss any doses.
- If you have any questions or concerns about it, ask your medical practitioner. They will suggest alternate options that suit your body’s needs.
[Note: If you have missed a dose of your medication and are unsure about when to take the next one, immediately consult your doctor or pharmacist.]
What Happens If You Take Too Much of Seretide Accuhaler?
Overdosing any medication is not a solution. While patients are educated enough to know the complications of excessive dosing, there are times when they accidentally take too much of the prescribed medication. In such situations, patients can experience unusual symptoms, including:
- Significant muscle tremor
- Headache
- Increased blood pressure
- Rapid heartbeat
- Increased rate of breathing
- High blood sugar
If you are experiencing such overdose symptoms, visit the nearest clinic or get medical assistance immediately by calling 911.
[Note: If you consumed more than the recommended dose, get medical help right away or call the Poison Help line at 1-800-222-1222.]
How to Store a Seretide Accuhaler?
- Store your Seretide accuhaler below 30°C.
- Keep the product in its original container/packaging.
- Store it somewhere safe, away from the reach and sight of children and pets.
- Protect the product from direct heat and sunlight.
- Avoid refrigerating the product because if your accuhaler becomes extremely cold, it may not work properly. So, keep it away from frost.
- Do not flush the medication down the toilet.
- Avoid keeping it in damp or moist places like the bathroom or near the sink.
- Do not store it in the car or on window sills.
- Do not use a medication if its expiration date has passed. The expiration date is the last day of the month mentioned on the back of the prescription label or carton.
- You should dispose of the medications in such a way that children and animals cannot consume them, as it may cause accidental overdose and death if someone else consumes them.
- Ask a medical professional how to dispose of the product properly without damaging the environment.
- The best way to eliminate unwanted medications is to give them in the medicine take-back program.
[Note: Discuss with your healthcare professional about the proper disposal of any unused medicine and any questions you may have regarding its storage.]
What Medications Interact with Seretide Accuhaler?
Drug interactions occur when one or more medications are taken simultaneously. These interactions can either raise the risk of developing side effects in certain patients or affect the functioning of one of the drugs. Either way, it results in adverse reactions. Therefore, patients need to be aware of the drugs that may interact with their Seretide accuhaler medication. Below are some of the drugs that can interact with Seretide (fluticasone propionate and salmeterol xinafoate):
- Blood pressure-lowering medications. Examples are:
- Propranolol
- Atenolol
- Water pills
- Anti-bacterial medications. Some of its examples are:
- Itraconazole
- Ketoconazole
- Erythromycin
- Anti-viral medicines, including:
- Ritonavir
- Cobicistat-containing products
- Other Drugs:
- Levacetylmethadol
- Atomoxetine
- Domperidone
- Methacholine
- Sotalol
- Astemizole
- Acetazolamide
- Vandetanib
- Sulpiride
- Sevoflurane
- Quinidine
- Propofol
[Note: This isn’t a complete list, and there could be other drugs that interact with Seretide Accuhaler. Make sure to tell your doctor about any prescription, over-the-counter medicines, and herbal products you’re taking.]
What Are the Seretide Accuhaler Alternatives?
People usually take alternative drugs for many reasons. In some cases, the prescribed medication may not be an ideal option for them due to their medical conditions. On the other hand, they may not achieve the results they are aiming for. Therefore, you should talk to a medical professional before you start a particular treatment or if you want to change your medication. They may help you decide which medication is best suited for you. Some of the alternatives of Seretide accuhaler (fluticasone propionate and salmeterol xinafoate) are as follows:
- Breztri Aerosphere
- Spiriva
- Albuterol
- Advair Diskus
- Symbicort
- Combivent
- Dulera
- AirDuo RespiClick
- Wixela Inhub
- Breo Ellipta
- Trelegy Ellipta
- Asmanex HFA
- Qvar RediHaler
- Flovent HFA
[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.]
Seretide Accuhaler Cost & Coupons
It is important to note that Seretide accuhaler’s cost is not the same everywhere. The actual price of these accuhalers depends on several factors, including your insurance plan, location, and the pharmacies you use. Seretide, with its healing qualities, can be expensive for certain patients. Here, insurance coverage plays a significant role. You can buy your medication at affordable rates with an insurance coverage plan. However, not all drugs/medications are covered under the insurance plan. If you are residing in America and searching for affordable pharmacies to manage your medication’s cost, reach out to Polar Bear Meds. Here, you can buy Seretide accuhaler online from Canada in the USA at discounted rates. Moreover, first-time buyers can use the Seretide accuhaler coupon code WELCOMEPB10 to receive a 10% discount on their first order.
Frequently Asked Questions
Is Seretide accuhaler safe for long-term use?
Seretide accuhaler is generally safe for long-term use when taken as prescribed by your healthcare provider. It helps manage chronic conditions like asthma and COPD effectively. However, regular medical check-ups are essential to monitor your condition & adjust the dosage if necessary. Always follow your doctor’s advice and promptly report any unusual symptoms or side effects.
Can I stop using Seretide accuhaler?
Do not stop using Seretide accuhaler without consulting your medical provider. Sudden discontinuation of the medication can result in a return or worsening of asthma or COPD symptoms. Your doctor will guide you on how to gradually reduce the dose if discontinuation is necessary. Proper medical guidance ensures your symptoms remain controlled and prevents potential health complications.
Can I drink water immediately after using Seretide accuhaler?
Yes, you can gargle with water immediately after using the Seretide accuhaler but do not swallow it. In fact, it is advisable to rinse your mouth with water after each use to prevent potential side effects like oral thrush. Rinsing mouth with water helps clear any residual medication from your mouth, maintains oral hygiene, and reduces the risk of infection. Additionally, it ensures that the medication is not inadvertently swallowed, enhancing its effectiveness in the lungs.
Can Seretide accuhaler cause weight gain?
Weight gain is not a common side effect of Seretide accuhaler. However, the corticosteroid component, fluticasone, can cause weight gain in some individuals, especially with long-term use. If you notice significant weight changes, discuss them with your healthcare provider. They can provide guidance on controlling side effects and maintaining a healthy weight while using the medication.
Does Seretide accuhaler contain steroids?
Yes, Seretide accuhaler contains fluticasone propionate, which is a corticosteroid. This ingredient helps reduce inflammation in the airways, making it easier to breathe. The medication also includes salmeterol xinafoate, a long-acting beta2-agonist that relaxes the airway muscles. Together, these components effectively manage asthma and COPD symptoms, providing relief and improving respiratory function.
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