Tranylcypromine

Parnate

Parnate is an effective medication that the FDA approves for the treatment of depression, primarily major depressive disorder in adults. While it is a chronic condition, it generally occurs in episodes. These depressive episodes can last for several weeks or months, thus making the patients suffer from severe depression. This disorder/condition causes persistently low mood and loss of interest in things that you previously enjoyed. Parnate is a prescription medication that can not be bought from pharmacies easily. Depression is a concerning mental health condition; therefore, people should not share their medication with others, even if they share the same condition. Doing so will increase the risk of side effects in other patients, which can be fatal. Lastly, if you have been prescribed this medication, always order Parnate tablets from a trusted pharmacy.

Product Overview

Parnate is a prescription medication approved by the FDA for treating major depressive disorder, or MDD, in adults. It contains the active ingredient Tranylcypromine, a potent monoamine oxidase inhibitor (MAOI). This disorder, also known as clinical depression, causes depressed mood and makes you lose interest in activities that once brought joy to you. Tranylcypromine works by increasing the levels of certain chemicals in the brain.

Parnate is available in tablet form, typically in a strength of 10 mg. It is taken orally, usually once or twice daily, as prescribed by a medical professional. It is essential to stick to the dosing instructions precisely. Parnate is intended for adults diagnosed with depression and is not recommended for children or adolescents. It works by restricting the monoamine oxidase enzyme, thereby preventing the breakdown of mood-regulating neurotransmitters and enhancing their activity in the brain.

Common side effects of this medication are dizziness, dry mouth, constipation, and insomnia. Patients are advised to avoid certain foods & beverages that contain high levels of tyramine, as this can cause dangerous increases in blood pressure. It is important to inform your healthcare provider of any other medications you are taking to avoid potential interactions. Do not double up on doses. In the event of a Parnate overdose, seek immediate medical attention. Store Parnate tablets at room temperature and out of the reach of children and pets. If you order Parnate tablets online, follow your healthcare provider’s guidance thoroughly and promptly report any unusual side effects.

What Is Parnate Prescribed For?

This medication is used for the following conditions:

• Depression
• Depressive psychosis
• Dementia with depressive features
• Arteriosclerotic dementia with depressive features

What Strengths & Forms Does Parnate Comes In?

Parnate is available in the form of an oral tablet with a strength of 10 mg.

What Are the Recommended Dosage of Parnate?

Parnate starting dose depends on various factors, including the type and severity of your medical condition, body weight, and the form of Parnate you take. Generally, doctors usually prescribe a starting dose and gradually adjust the doses of the medication as needed. It is important to note that these dosage recommendations are only the average dose. So, if you have been prescribed a different dose, do not change it without consulting your medical practitioner.

Recommended Dosage

Doctors usually recommend taking a 30 mg dose of Parnate each day in divided doses. If you do not respond adequately, your medical practitioner will increase the dosage by 10 mg daily every 1 to 3 weeks. The maximum daily dose of Parnate is 30 mg twice daily, i.e., 60 mg per day. 

Switching from Other Antidepressants to Parnate

• If you were previously taking contraindicated antidepressants with Parnate, wait for 4 to 5 half-lives of the other antidepressant or any active metabolite to pass before starting the treatment with Parnate. 
• If you were taking an MAO inhibitor antidepressant, wait for at least one week before starting Parnate. This helps reduce the risk of additive effects.

Switching from Parnate to Other MAOIs or Contraindicated Antidepressants:

• After stopping Parnate treatment, wait for at least one week before starting another MAOI or any other antidepressant that is contraindicated.

[Note: Remember, these recommendations may vary from person to person. Discuss it with your doctor, and they’ll customize your dosage accordingly.]

How to Take Parnate?

If you plan to buy Parnate online, you must know the proper administration steps to get the best results from the medication. Here are some important steps on how to take Parnate:

• Before jumping on the administration steps, read your medication guide or patient information leaflet thoroughly to understand the information in detail. If you have any doubts, ask your medical professional.
• Take Parnate by mouth with or without food unless your doctor prescribes otherwise. 
• Swallow the tablets as a whole with a glass of water or as your practitioner instructed.
• Avoid breaking, chewing, or crushing the medicine, as this will release the drug at once.
• If you are unable to swallow the tablets, visit your healthcare practitioner. They will suggest alternate options that suit your needs.
• Do not exceed or subceed your medication’s doses without consulting a medical professional. Doing so can cause severe side effects.
• Stop taking this medication if you are undergoing surgery or any medical procedure.
• Complete the course of your treatment even if you feel better.
• Do not discontinue the use of Parnate abruptly. This will result in withdrawal symptoms like confusion, restlessness, headache, hallucinations, diarrhea, and weakness. 
• Try to take the doses simultaneously every day to get the most benefit from it.

[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They’ll adjust it as needed over time.]

What Is the Mechanism of Action for Parnate?

Parnate, containing Tranylcypromine, works by restricting the enzyme monoamine oxidase (MAO). This enzyme breaks down neurotransmitters in the brain, including serotonin, norepinephrine, and dopamine. By blocking these MAO inhibitors, Parnate increases the levels of these mood-regulating chemicals. This expansion helps improve mood and reduce depressive symptoms. The enhanced presence of these neurotransmitters leads to improved communication between brain cells, contributing to the antidepressant effects of Parnate. This mechanism makes Parnate an effective treatment for major depressive disorder, providing relief from the symptoms of depression.

Important Safety Information for Using Parnate

What Are the Side Effects of Parnate?

Common Side Effects of Parnate: This medication can cause some common reactions in certain patients that are generally temporary. These effects last from a few days to weeks. However, if any of the side effects last longer than the described period, get intense, or bother you, contact your healthcare provider right away. Common side effects of Parnate may include:

• Weakness: This medication can lower blood pressure, reducing oxygen and nutrients flow to muscles. Due to this, you can feel tired or weakness after taking Parnate. This side effect is common and may disappear within a few days or weeks.
• Drowsiness: Parnate can cause drowsiness by increasing serotonin and other neurotransmitter levels, which may alter the balance between wakefulness and sleep signals in the brain. It can also lead to sedation as a side effect of its effects on central nervous system activity.
• Nausea: This medication affects certain chemicals in the brain, which can lead to gastrointestinal disturbanes, thus making you feel nauseous. Additionally, it can also interact with other substances like tyramine-rich foods, causing nausea. If you experience persistent nausea, talk to your doctor.
• Frequent Headaches: Many people experience frequent headaches after taking this medication. This is a common side effect that usually occurs when your body tries to adjust to the drug’s effects. Once you get used to the drug, this side effect will diminish.
• Vision Changes: Affected blood vessles in the eyes can lead to fluctuations in blood flow and pressure. As a result you notice vision changes symptoms like blurred vision, seeing halos around light, and other visual disturbancecs. 
• Stomach Pain: When you take Parnate for depression treatment, it irritates the stomach lining, leading to pain and discomfort around the stomach area. This pain is usually mild and may lessen over time. 
• Restlessness: An affected neurotransmitter levels in the brain can cause restlessness in certain patients, leading to increased nervous system activity. This effect can cause feelings of agitation, anxiety, and inability to stay still. 
• Not Feeling Hungry: Similar to the above side effect, Parnate can affect the brain’s neurotransmitter levels, which are responsible for controlling hunger. This can lead to reduced desire to eat, making you feel less hungry than usual. Moreover, the medication can cause gastrointestinal effects, contributing to reduced appetite.
• Diarrhea: This medication can affects your digestive system, leading to increased bowel movements and irritation of the intestines. In this side effect, you can experience loose and watery stools associated with stomach discomfort. 
• Constipation: Parnate can cause constipation because it affects the muscles & nerves in your digestive tract, slowing down bowel movements. This side effect is indicated by difficulty passing stools and infrequent bowel movements. Additionally, the medication can reduce the secretion of fluids in the intestines, making stools harder and more difficult to pass.
• Chills: Parnate can control your body’s temperature. This regulation interferes with the normal functioning of your nervous system, leading to fluctuations in body temperature and making you feel cold or shivering. Additionally, it can also cause other symptoms like fever, contributing to the sensation of chills.
• Less Urination: Your urine output may lower due to the medication’s effects on the muscles and nerves that control your bladder. This can cause a decrease in the frequency and volume of urine. Additionally, the medication can cause dehydration or interact with other substances, further reducing urine output.
• Dry Mouth: Many users have noticed dry mouth after taking Parnate as the medication affects the saliva production in the mouth. This can lead to reduced saliva, making your mouth feel dry and uncomfortable. 
• Numbness: Tranylcypromine can cause numbness feeling as it affects the nerve signals, leading to sensations like tingling or loss of feeling in certain parts of your body.
• Ringing in Your Ears: This condition is also known as tinnitus, and it usually happens when the medication affects the auditory nerves and blood flow to the inner ear. However, this side effect is experienced at the start of the treatment and does not require any immediate medical attention.
• Difficulty Having an Orgasm: Parnate may interfere with certain neurotransmitters that regulate sexual functions. This alteration can make it harder for people to reach orgasm. This side effect is not severe, but if it impacts your personal life, reach out to a medical professional. 
• Difficulty While Sleeping: The medication can disturb sleep patterns by impacting neurotransmitters that control sleep, leading to insomnia or restless sleep.
• Impotence: Many Parnate users have noticed impotence after using this medication. This side effect happens as the drugs affect the blood flow and nerve signals that are essential for achieving and maintaining an erection.

Serious Side Effects of Parnate: Besides basic side effects, Parnate can also lead to adverse impacts that can cause life-threatening situations if left untreated. Therefore, if you are experiencing any unusual side effects that may seem severe to you, reach out to your nearest medical practitioner. Serious side effects of Parnate may include:

• Fainting: There are chances that this medication can reduce blood flow to the brain, causing lower blood pressure. This fluctuation in blood pressure levels can lead to fainting, especially when standing suddenly. If it is mild it can be controlled, but severe low levels of blood pressure can result in adverse complications.
• Mood Changes: Parnate alters serotonin and norepinephrine levels, affecting mood and mental clarity. These changes can make the brain overactive, leading to feelings of agitation, confusion, or emotional instability.
• Muscle Stiffness: Tranylcypromine effects on dopamine and serotonin levels can overstimulate muscle control. This can further lead to increased tension or stiffness in the muscles.
• Tremor or Shaking: By altering neurotransmitters like dopamine, Parnate can interfere with the normal control of muscle movements, causing involuntary shaking or tremors.
• Edema: This is a medical condition where fluid builds up in the body’s tissues, leading to swelling. So, when you take Parnate for depression treatment, the components present in the medication affect fluid balance and circulation, causing fluid retention, especially in the lower extremities, like ankles and legs.
• Sudden Weight Gain: Fluid retention and changes in metabolism can lead to sudden weight gain in certain patients. This change in body weight is not related to any dietary intake or physical activity. 
• Abnormally High Blood Pressure: Parnate has many interactions, and tyramine is one of them. If you consume food rich in tyramine, it can cause increased norepinephrine levels. This can constrict blood vessels, leading to dangerously high blood pressure. 
• Severe Eye Problems: This medication can raise eye pressure and affect blood flow to ocular tissues, potentially leading to serious eye issues such as glaucoma. If you experience any of the following symptoms, report it to your doctor:
  • Sudden vision loss
  • Eye pain
  • Eye swelling
  • Seeing halos around light
  • Tunnel vision
  • Blurred vision
• Heart Problems: High norepinephrine levels can overstimulate the heart, causing various heart issues. This happens due to the drug’s effects on the body. If you notice any of the below signs, seek immediate medical attention:
  • Irregular or rapid heartbeat
  • Chest fluttering
  • Breath shortness
  • Dizziness
  • Lightheartedness
  • Fainting
• Slurred Speech: The medication can disrupt how nerves control the muscles, which is important for speaking. This alteration makes it harder to form clear words or causes slurred speech.
• Weakness on Arm or Leg: Tranylcypromine may disrupt the blood flow to certain areas of the body, leading to weakness in an arm or leg. As a result, making movements can become difficult for you.
• Difficulty in Walking: By affecting brain areas that controls movement and balance, this medication can cause problems with walking, such as unsteady or jerky steps. This side effect can become severe if left untreated and cause various problems in performing daily activities.
• Loss of Coordination: Due to durg’s effect on the brain, you may lose the ability to control precise muscles movements. This can cause difficulty in performing coordinated actions like writing or reaching for objects.
• Unsteadiness: Parnate may affect brain chemicals that help with balance, making it harder to stay stable while standing or walking, increasing the risk of falls. If not treated timely, it can cause life-threatening situations.
• High Fever: The medication can overstimulate the nervous system & interfere with the body’s ability to control temperature, often causing dangerously high fevers, especially in serotonin syndrome.
• Excessive Sweating: Tranylcypromine can increase your norepinephrine levels, overactivating sweat glands. This rise can lead to excessive sweating even when you are not physically active.

[Note: Remember, this list may not cover all possible side effects. Always consult with your healthcare giver for medical advice about side effects.]

Are There Any Warnings for Parnate? 

Parnate can cause severe side effects in certain patients, or it may not be a suitable treatment option for specific populations due to their medical conditions. So, if you are using Parnate for depression treatment, you should remain cautious as it has several warnings, which are as follows:

• Serotonin Syndrome: Cases of serotonin syndrome, a potentially life-threatening condition, have been reported by patients when used Parnate with other serotonergic drugs such as SSRIs, SNRIs, tricyclic antidepressants, and others. Its symptoms may include mental changes, autonomic instability, neuromuscular issues, seizures, and gastrointestinal problems. If you are noticing such signs, discontinue the use of Parnate with the mentioned drugs.  
• Activation of Mania or Hypomania: Parnate can trigger manic/hypomanic episodes in people with bipolar disorder. Examine patients for a personal or family history of bipolar disorder, mania, or hypomania before starting this medication. Monitor patients closely for any signs of mania during treatment.
• Hypotension: Parnate can cause hypotension, including postural hypotension, especially at doses above 30 mg daily. Its symptoms include dizziness and fainting, particularly in patients with existing hypertension. Gradually increase doses in susceptible individuals and monitor for blood pressure changes. Lying down can help relieve postural hypotension. Be cautious of additive effects when used with other hypotensive agents.
• Hypotension and Hypertension during Anesthesia and Perioperative Care: Discontinue Parnate at least ten days before elective surgery. If this is not possible, avoid anesthetics and techniques that increase the risk of hypotension or hypertension. Carefully assess the risks of using such agents and adjust perioperative care accordingly.
• Hepatotoxicity: Parnate can cause hepatitis and increased aminotransferases. Therefore, patients need to monitor their liver function regularly. If you are experiencing any signs of liver toxicity, discontinue its use immediately. Moreover, patients with cirrhosis have an increased risk of central nervous system (CNS) side effects, such as excessive drowsiness, so they should also be monitored closely.
• Hypoglycemia in Diabetic Patients: Parnate can cause hypoglycemia in diabetic patients taking insulin or other glucose-lowering agents. Doctors should monitor their patient’s blood glucose levels closely and adjust the dosage of glucose-lowering medications to prevent hypoglycemic episodes.

What Are the FDA Boxed Warning for Parnate?

Boxed warnings are issued by the FDA for a particular drug to alert doctors and patients about its harmful effects. By knowing these warnings, you can take preventive measures to avoid potential risks. Parnate also received certain boxed warnings that are as follows:

• Suicidal Thoughts and Behaviors in Adolescents & Young Adults: Clinical studies have shown a high risk of suicidal thoughts and behaviors in patients using antidepressants. These patients were majorly among the age group of under 24 years. The risks may vary depending on the drugs patients use, but the highest risk was observed in patients with major depressive disorder (MDD). There is no specific data on whether the risk of suicidal thoughts & behavior in children, adolescents, and young adults is due to prolonged use of the medication (usually more than four months). Additionally, antidepressants can delay depression recurrence but may also increase suicidal thoughts. To ensure patient safety, the FDA suggests doctors monitor their patients for clinical worsening, emergence of suicidal thoughts, and behavior changes during initial drug therapy and dosage adjustments.  
• Hypertensive Crisis and Hypertension: Excessive consumption of foods and beverages containing tyramine can increase the chances of developing a hypertensive crisis. Additionally, co-administration of Parnate with other drugs can trigger a hypertensive crisis. Patients should frequently monitor their blood pressure and make sure there’s enough time between taking Parnate and other medications. Additionally, avoid food or beverages with tyramine-rich content.

What Are the Precautions for Parnate?

When considering treatment with Parnate, patients should discuss every risk and benefit with their medical practitioner. Here are some of the precautions that you can take before using Parnate for major depressive disorder:

• Before starting your treatment with Parnate (Tranylcypromine), ensure that you tell your medical practitioner about your allergies or if you are allergic to any of the medication’s ingredients. The product may contain certain inactive components, causing adverse allergic reactions. 
• When undergoing surgery or a medical procedure that requires contrast dye usage, like myelography, inform your healthcare provider about the products you use. This includes all prescription medications, over-the-counter drugs, and herbal products.
• If you plan to order Parnate tablets online, tell your medical practitioner about your or your family’s medical history, especially if it is:
  • Cerebrovascular disease
  • High blood pressure
  • Heart problems
  • Frequent headaches
  • Mental disorders
  • Pheochromocytoma (type of adrenal gland tumor)
  • Liver problems
  • Kidney issues
  • Parkinson’s syndrome
  • Seizures
  • Overactive thyroid
  • Glaucoma
• Patients with heart problems should not use this medication as it can cause chest pain. So, avoid doing intense exercise while taking Parnate.
• This medication may make you dizzy or drowsy. Substances like alcohol and marijuana can worsen this condition. Therefore, patients taking this medication are advised not to drive or use heavy machines that require alertness.  
• Diabetic patients should remain cautious while taking this medication. Parnate may lower your blood glucose levels, so you should examine your sugar levels regularly and share the reading with a professional practitioner. If you have noticed signs like rapid heartbeat, hunger, blurred vision, dizziness, sudden sweating, shaking, or tingling in your hands or feet, immediately visit your healthcare provider.
• Parnate is suitable for adult use. Older patients should avoid this medication as they are more likely to experience its side effects, especially effects on their blood pressure.
• If you are pregnant or planning to have a baby, avoid using this drug unless it is clearly needed. This drug may cause harm to the developing fetus. Discuss every risk and benefit with a medical practitioner before making any decision.
• Parnate can enter into breast milk. So, if you are a nursing mother, talk to an expert physician before breastfeeding your child.
• Mental disorders like depression are a serious problem. So, do not abruptly discontinue the use of Parnate, as it can cause withdrawal symptoms like nausea, dizziness, irritability, headache, and insomnia. Talk to a professional and discuss your situation; they will gradually lower your dose instead of stopping it suddenly. 
• After stopping Parnate, the effects of MAO inhibition can last up to 10 days. Be cautious when using other substances or consuming foods high in tyramine.
• If emergency treatment with a drug that interacts with Parnate is necessary, stop Parnate promptly and monitor the patient closely for adverse reactions. Examples of such drugs include linezolid, intravenous methylene blue, and direct-acting sympathomimetics like epinephrine.
• This medication may exacerbate anxiety and agitation in depressed patients. If such people are using Parnate, closely monitor them for increased anxiety and agitation. 

What Are the Contraindications for Parnate?

This medication is contraindicated in:

• Patients who have confirmed or suspected cerebrovascular defects/cardiovascular disorders.
• Patients with pheochromocytoma
• Combination with certain drugs, including 
  • MAO inhibitors
  • SSRIs
  • SNRIs
  • Tricyclic antidepressants 
  • Bupropion 
  • Buspirone
  • Sympathomimetics 
  • Meperidine
  • Dextromethorphan

What If You Missed a Dose of Parnate?

Generally, doctors recommend not to miss a dose of Parnate, but if you have forgotten a dose of your medication:

• Take the medication as soon as possible or whenever you remember.
• If it is almost time for the next dose, you may omit the missed dose and continue your usual dosing schedule.
• Remember not to take double doses of Parnate at the same time, as it can increase the risk of side effects.
• Use medication apps or set reminders on your phone to avoid skipping any doses.
• You can use a pill box for timely medication administration. These boxes have separate compartments for each week. You can organize your doses weekly. 
• If you are still unsure about the missed dose, consult a medical professional. 

[Note: If you have missed a dose of your medication and are unsure about when to take the next one, immediately consult your doctor or pharmacist.]

What Happens If You Take Too Much of Parnate?

Doctors usually advise not to take extra doses of Parnate as this medication can cause adverse reactions if overdosed. However, if you have mistakenly overdosed and are experiencing any unusual symptoms, visit the nearest clinic. Symptoms of Parnate overdose may include:

• Insomnia
• Dizziness
• Weakness
• Hypotension
• Anxiety
• Restlessness
• Mental confusion
• Agitation
• Seizures
• Hypertension associated with severe headache
• Myoclonic fibrillation of skeletal muscles (twitching)

If you notice any of the above symptoms, discontinue the use of Parnate immediately and seek medical assistance or call 911.

[Note: If you consumed more than the recommended dose, get medical help right away or call the Poison Help line at 1-800-222-1222.]

How to Store a Parnate?

To maintain the long term effectiveness and safety of your medication, proper storage is important. If you plan to buy Parnate online, follow the below storage guidelines to keep your medication safe. 

• Store the product at a controlled room temperature within 15° to 30°C/59° to 86°F.
• Keep the medication in its original packaging and store it in a tight and light-resistant container.
• Place a safety lock on the container to avoid poisoning your child or pet, as many medication containers are not child-resistant.
• Store the medication somewhere safe, away from out of reach and sight of children and pets.
• Do not flush the medication down the toilet.
• Avoid keeping your tablets in damp or moist areas like the bathroom or near the sink.
• Protect the medication from light and moisture.
• Do not keep it under direct sunlight.
• Discard the medication when it is not in use or reaches its expiration date.
• You should dispose of your medications in such a way that children and animals cannot consume them, as it may cause accidental overdose and death if someone else consumes them.
• The best way to eliminate unwanted medications is to give them in the medicine take-back program.
• Ask a medical professional or pharmacist how to properly dispose of the product without damaging the environment.

[Note: Discuss with your healthcare professional about the proper disposal of any unused medicine and any questions you may have regarding its storage.]

What Medications Interact with Parnate?

Drug interactions occur when one or more medications are taken simultaneously. These interactions can either raise the risk of developing side effects in certain patients or it can affect the functioning of one of the drugs. Either way, it results in adverse reactions. Therefore, patients need to be aware of the drugs that may interact with their Parnate medication. Below are some of the drugs that can interact with Parnate (Tranylcypromine):

• Acrivastine
• Almotriptan
• Amezinium
• Amineptine
• Benzphetamine
• Brimonidine
• Bromodiphenhydramine
• Brompheniramine
• Buclizine
• Chlorphenoxamine
• Cinnarizine
• Citalopram
• Clemastine
• Desipramine
• Desvenlafaxine
• Eletriptan
• Entacapone
• Femoxetine
• Fenfluramine
• Flunarizine
• Fluoxetine
• Guanadrel
• Guanethidine
• Hydroxytryptophan
• Hydroxyzine
• Isocarboxazid
• Isoetharine
• Isometheptene
• Levodopa
• Levomethadyl
• Melitracen
• Meperidine
• Mephentermine
• Metaraminol
• Norepinephrine
• Nortriptyline
• Opicapone
• Opipramol
• Pheniramine
• Reserpine
• Sertraline
• Tramadol
• Vortioxetine
• Zolmitriptan

What Are the Other Parnate Interactions?

Besides drug interactions, there are other Parnate interactions too:

• Tyramine-rich food
• Hyperthyroidism
• Alcohol
• Hypertension/CVD
• Liver disease
• Pheochromocytoma
• Hypoglycemia
• Parkinsonism
• Schizophrenia/Bipolar
• Seizures
• Angina
• Bipolar disorder screening
• Diabetes
• Hypotension
• Renal disease

[Note: This isn’t a complete list, and there could be other drugs that interact with Parnate. Make sure to tell your doctor about any prescription, over-the-counter medicines, and herbal products you’re taking.]

What Are the Alternatives to Tranylcypromine (Parnate)?

People usually take alternative drugs for many reasons. In some cases, the prescribed medication may not be an ideal option for them due to their medical conditions. On the other hand, they may not achieve the results they are aiming for. Therefore, you should talk to a medical professional before you start a particular treatment or if you want to change your medication. They may help you decide which medication is best suited for you. Some of the alternatives of Parnate are as follows:

• Bupropion 
• Cymbalta
• Sertraline
• Lexapro
• Zoloft
• Citalopram
• Fluoxetine
• Wellbutrin XL

[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.]

Parnate Cost & Coupons

It is important to note that the cost of Parnate is not the same everywhere. The actual price of these tablets depends on several factors, including your insurance plan, location, and the pharmacies you use. Parnate, with its therapeutic qualities, can be a bit expensive for certain patients. Here, insurance coverage plays a significant role. You can buy your medication at affordable rates with an insurance coverage plan. However, not all drugs/medications are covered under the insurance plan. If you are residing in America and searching for affordable pharmacies to manage your medication’s cost, reach out to Polar Bear Meds. Here you can buy Parnate online from Canada in the USA at discounted rates. Moreover, first-time buyers can use the Parnate coupon code WELCOMEPB10 to receive a 10% discount on their first order.

Frequently Asked Questions

Does Parnate come under the controlled substance?

No, Parnate is not classified as a controlled substance. However, it is a prescription medication and should be used under the supervision of a healthcare provider. It is essential to adhere to your physician’s instructions and only use Parnate as directed to ensure safety and effectiveness in treating major depressive disorder.

Which foods should I avoid while taking Parnate?

While taking Parnate, avoid foods high in tyramine, such as aged cheeses, cured meats, fermented foods, and certain alcoholic beverages like red wine and beer. Consuming these foods can cause dangerous increases in blood pressure. Moreover, it is always best to talk to a medical professional for a personalized diet chart. They will provide a complete list of foods that you must avoid and adhere strictly to these dietary restrictions.

Does Parnate affect my sleep?

Yes, Parnate can affect your sleep cycle. Some patients may experience insomnia or difficulty sleeping while taking this medication. If you notice major changes in your sleep or have trouble sleeping, inform an expert physician, who may adjust your dosage or suggest ways to manage this side effect, ensuring your overall treatment remains effective.

Will I gain weight during my treatment with Parnate?

Weight gain is not a common side effect of Parnate. However, individual responses to medications can vary. If you experience noticeable changes in your weight, discuss this with your medical practitioner. They can help determine the cause, suggest appropriate measures to manage any weight-related concerns and adjust your treatment plan if necessary.

What happens if I stop taking Parnate? 

Stopping Parnate abruptly can lead to withdrawal symptoms and recurrence of depressive symptoms. It is important to follow your medical provider’s guidance when discontinuing the medication. They will usually recommend gradually tapering off the dose to minimize withdrawal effects and ensure a safe discontinuation process, reducing the risk of adverse effects.

Is Parnate sedating?

Yes, Parnate can be sedating for certain patients and can cause drowsiness, sleepiness, and dizziness, particularly at the start of your treatment. At the same time, some people also experience stimulating effects like high energy and alertness. To know how this medication affects your body, consult a medical professional. 

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