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What Is Apidra Insulin Glulisine Injection?
Apidra is a brand name of for insulin glulisine, which is a rapid-acting insulin analog. Like all insulin analogs, it is a genetically modified version of naturally occurring human insulin. Rapid-acting insulin analogs are sometimes referred to as mealtime or bolus insulin because they help to regulate your blood sugar levels right after mealtime.
Apidra is currently the only mealtime insulin approved for you to take within 20 minutes after or within 15 minutes before starting a meal. It is taken as a subcutaneous (under the skin) injection and has a more rapid onset and a shorter duration of action compared to naturally occurring human insulin.
What Is Apidra Insulin Used For?
Apidra is for the treatment of adults or children (6 years and older) with type 1 or type 2 diabetes. It helps to improve blood sugar regulation. It is given by subcutaneous injection and is typically used with longer-acting basal background insulin to help give you a full day of protection against blood sugar fluctuations. Together with regular exercise, a healthy diet plan, and longer-acting insulin, this has been shown to help decrease blood sugar levels in children (6 years and older and adults with type I diabetes or adults with type II diabetes.
How Does Apidra Insulin Work?
The main therapeutic activity of insulin and insulin analogs is the control of sugar breakdown from food (carbohydrates, fats and proteins). Insulin helps lower blood sugar levels by activating blood sugar absorption by skeletal muscle and fat cells and preventing the liver from producing and releasing more sugar into the blood.
Apidra Vial has the same effect on blood sugar levels as naturally occurring human insulin when administered intravenously (into the vein). Still, when administered through subcutaneous (under the skin) injection, as with the Apidra SoloSTAR Insulin Pen, the effects are more rapid and have a shorter duration than naturally occurring human insulin.
Warnings Related to Apidra
The following are some of the most common warnings associated with Apidra:
- Taking Apidra can lower your blood glucose (sugar) levels, possibly leading to hypoglycemia.
- Even though Apidra works by lowering blood sugar levels, in some situations, such as illness or stress, your blood sugar levels may rise (hyperglycemia).
- There is a possibility that Apidra can cause a decrease in blood potassium levels (Hypokalemia).
- It is possible to experience injection site reactions with Apidra, including redness, swelling, or itchiness.
- An allergic reaction to insulin (including Apidra) may occur in rare cases.
- Women who are pregnant or breastfeeding should consult a healthcare professional before using Apidra. Insulin needs may change during this time.
What Are the Pros & Cons of the Apidra SoloSTAR Pen?
Pros of Apidra
- Works quickly to lower blood sugar.
- In addition to the vial, a prefilled pen is also available, which can be easier to use.
- If a patient is in the hospital and needs better control of their blood sugar levels, this can be given as an IV injection (intravenous means in a vein).
- Suitable for continuous insulin pumps.
- A dose adjustment is easily possible.
Cons of Apidra
- The medication should be administered multiple times a day (before each meal).
- It needs to be injected into the body
- It might be difficult for some people to administer this medication
- There is a high risk of low blood glucose levels.
- You can also gain weight as a result of this medication.
- Contains no other insulins (except NPH insulin) that can be mixed together in the same syringe.
Does Apidra Solostar Insulin Interact with Any Other Medications?
A potential interaction between insulin glulisine and any of the following drugs may be possible:
- ACE Inhibitors
- Atypical Antipsychotics
- Inhaled Corticosteroids
- Oral Corticosteroids
- Diabetes Medications
- Hepatitis C Antivirals
- HIV Protease Inhibitors
- Monoamine Oxidase Inhibitors
- Oral Contraceptives
- Quinolone Antibiotics
- St. John’s Wort
- Selective Serotonin Reuptake Inhibitors
- Thyroid Replacement Hormones
Frequently Asked Questions
Is it necessary to refrigerate Apidra?
In the case of unopened Apidra vials & Apidra SoloSTAR Pen®, keep them in a refrigerator between 36°F & 46°F (2°C and 8°C). Protect them from light. Do not freeze Apidra. If it has frozen, discard it.
Are there any side effects associated with Apidra insulin?
The following are common side effects:
- Blood sugar levels are low
- The skin may itch or develop a mild rash.
- Where the medicine was injected, the skin thickened or hollowed out.
What is the fast-acting nature of Apidra insulin?
There is only one mealtime insulin that is approved for use within 15 minutes before or within 20 minutes after a meal begins, called Apidra SoloSTAR®. Apidra is the only mealtime insulin that is approved for use within 15 minutes before or within 20 minutes after starting a meal.
How long does Apidra take to act?
There is a rapid-acting insulin analog called Apidra that has been shown to improve the glycemic control in patients with diabetes, both adults and children. Apidra’s use during mealtime should be performed within 15 minutes after starting a meal or within 20 minutes after starting a meal if it is being used in between meals.
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