Salmeterol 

Salmeterol Xinafoate 

Salmeterol Xinafoate is a long-acting bronchodilator used to prevent asthma and treat chronic obstructive pulmonary disease. It contains Salmeterol as its main ingredient that stimulates beta-2 receptors in the bronchial muscles, causing them to relax and open the airways. It is suitable for adults and children over four years old, particularly those who require long-term asthma or COPD management. Salmeterol comes in the form of an inhalation powder that is typically combined with fluticasone. It has 100 mcg, 250 mcg, and 500 mcg of fluticasone, with each dose containing 50 mcg of salmeterol strengths. You should consult a licensed healthcare practitioner for any concerns or queries regarding the medication use. You can buy salmeterol xinafoate online at the best prices from reputable sources to ensure your medication is safe and authentic.

Product Overview

Salmeterol Xinafoate is a long-acting bronchodilator used to treat asthma & chronic obstructive pulmonary disease (COPD). The main ingredient, Salmeterol, works by stimulating beta-2 receptors in the bronchial muscles, causing them to relax and open the airways. This action helps to prevent and manage symptoms such as shortness of breath, wheezing, and chest tightness.

Salmeterol Xinafoate is available in the form of an inhalation powder, typically combined with fluticasone. The strengths include 100 mcg, 250 mcg, and 500 mcg of fluticasone, with each dose containing 50 mcg of Salmeterol. This medication is taken via an inhaler device, following a specific dosage regimen as directed by a healthcare provider. It is suitable for adults and children over four years old, particularly those who require long-term asthma or COPD management.

While using Salmeterol Xinafoate, patients may experience side effects such as headache, throat irritation, muscle cramps, and rapid heartbeat. Serious side effects can include paradoxical bronchospasm and severe allergic reactions. Patients should take precautions by using this medication exactly as prescribed, not exceeding the recommended dose. In case of a missed dose, take it as soon as remembered unless it is nearly time for the next dose. Do not double up doses. Store Salmeterol Xinafoate in a cool, dry place, away from direct sunlight and moisture. For any concerns or adverse effects, consult a healthcare professional immediately. Always follow medical advice and the prescribed treatment plan to ensure safe and efficient use of Salmeterol Xinafoate.

What Are the Uses of Salmeterol Xinafoate?

It is used to:

• Prevent asthma attacks
• Treat chronic obstructive pulmonary disease

What Are the Forms & Strengths of Salmeterol Xinafoate?

Salmeterol Xinafoate comes in the form of an inhalation powder with the strengths of:

• Fluticasone: 100 mcg, 250 mcg, 500 mcg
• 50 mcg of Salmeterol

What Are the Recommended Dosage of Salmeterol Xinafoate?

For Asthma

Adults and adolescents (12 years and older):

• Typically 50 mcg (1 inhalation) twice daily, approximately 12 hours apart
• The maximum recommended dose is 100 mcg twice daily

Children (4-11 years):

• Usually 50 mcg (1 inhalation) twice daily

For Chronic Obstructive Pulmonary Disease (COPD):

Adults: 50 mcg (1 inhalation) twice daily

[Note: Remember, these recommendations may vary from person to person. Discuss it with your doctor, and they’ll customize your dosage accordingly.]

How to Use Salmeterol Xinafoate? 

Salmeterol is used to prevent asthma attacks & treat COPD. It is not used to treat an occuring asthma attack. To provide relief from an asthma attack that has already begun, you should use another medication. If you do not have another medication to use for an asthma attack, you should check with your doctor. To use Salmeterol for safe and efficient use, you should follow the given instructions:

• You should use this medication exactly as your doctor directed. Do not use more or less of it, more frequently, or in large quantities. 
• Before starting to take this medication, each time you get a refill, you should carefully read and follow the instructions for use that came along with this prescription medication. 
• Ask your physician or medical provider if you do not understand any part of the leaflet. 
• You should not stop using this medication without asking your doctor, as it may worsen your condition. Tell your doctor if you are planning to discontinue using this medicine. 
• For this medication to help prevent asthma or COPD attacks, you should maintain consistency in dosage and try to take it around the same time every day. 
• Ask your doctor to see how you use the inhaler regularly to ensure that you are using it properly. 

Follow the guidelines given below to use Salmeterol properly:

• Carefully open the pouch containing the medication. 
• To open the diskus, push your thumb from your body as far as it will go. You will hear a click sound and feel a snap. After this, the mouthpiece will appear.
• Slide the mouthpiece lever away from you until it clicks. It is now ready for use. 
• In this stage, if you push the lever away or close the diskus, you will lose the drug. 
• Breathe out normally and turn your head away from the diskus. Do not breathe into it.
• Hold the diskus at the level of your mouth and put it between your lips and mouth.
• Close your lips around the mouthpiece, but do not block the mouthpiece with your mouth. 
• Breathe in using your mouth as deeply as possible until you have taken a completely deep breath. 
• You should not breathe through your nose. 
• Hold your breath for ten seconds or while you remove the mouthpiece. Continue holding your breath as long as possible or for ten seconds, whichever comes first. This gives the medication time to settle in your lungs and airways. 
• Turn your head away from the diskus and breathe out slowly. 
• If your doctor has prescribed you more than one puff, you should take the second puff using the same steps you used for the first one. 
• When you are done, close the diskus. 
• To do so, place your thumb on the grip and slide it back towards you as far as possible until you hear a clicking sound. 
• You should keep the diskus dry at all times. Do not wash the mouthpiece or any part of the diskus. To clean it, you may use a dry cloth. 
• The diskus has a window showing the number of doses left in it. This helps you determine when you are going to run out of this medication. 
• When the window of the diskus shows that there are five doses left, you should refill your prescription. 
• If your condition does not improve or worsens, you should call your doctor. 
• Do not share this medication with others, even if they have the same symptoms as you.  

[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They’ll adjust it as needed over time.]

How Does Salmeterol Xinafoate Work?

Salmeterol xinafoate, a long-acting adrenergic receptor agonist (LABA), is crucial in managing asthma and chronic obstructive pulmonary disease (COPD) symptoms. It stimulates beta-2 receptors present in the bronchial muscles. Beta-2 receptors are part of the sympathetic nervous system and are involved in bronchodilation. By binding to these receptors, Salmeterol causes the bronchial muscles to relax, opening airways. This effect helps prevent and alleviate symptoms such as shortness of breath, wheezing, coughing, and chest tightness. It acts on the enzyme adenyl cyclase, increasing the concentration of cyclic adenosine monophosphate. Elevated cAMP levels reduce smooth muscle tone in the airways.

Important Safety Information for Using Salmeterol Xinafoate

What Are the Side Effects of Salmeterol Xinafoate?

Like every other medication, Salmeterol can cause side effects. Not all users will experience these side effects. These side effects don’t always require medical attention and go away on their own within a few days or weeks. The benefits of using salmeterol xinafoate often outweigh the risks for many patients. If you are concerned about the unwanted side effects, consult your doctor before using Salmeterol. Common side effects caused by salmeterol xinafoate are listed below: 

• Headache
• Throat irritation
• Muscle cramps
• Tremors (especially in the hands)
• Nervousness or anxiety
• Rapid heartbeat (tachycardia)
• Palpitations
• Nausea
• Dizziness
• Fatigue

Less common side effects of salmeterol xinafoate are listed below:

• Chest pain
• Irregular heartbeat (arrhythmia)
• High blood pressure
• Insomnia
• Skin rash or allergic reactions
• Changes in blood sugar levels
• Dry mouth
• Difficulty urinating
• Increased sweating
• Muscle pain or weakness

In rare cases, Salmeterol may cause severe side effects in some people. These side effects often require immediate medical attention and may be fatal if not treated on time. You should immediately report any unusual or severe side effects to your healthcare provider. Serious side effects caused by salmeterol xinafoate are as follows:

• Paradoxical bronchospasm: This is a sudden, unexpected tightening of the airways. Its symptoms may include increased wheezing, coughing, and difficulty breathing.
• Severe allergic reactions (anaphylaxis): It can lead to shock and be life-threatening if not treated properly. Its symptoms may include hives, swelling of the face/throat, difficulty breathing, and rapid pulse.
• Cardiovascular events: It is more common in patients with pre-existing heart conditions. It may include the risk of heart attacks, strokes, and arrhythmias. It may manifest as chest pain, irregular heartbeat, or shortness of breath. 
• Hypokalemia (low potassium levels): It can cause muscle cramps, weakness, fatigue, and, in severe cases, heart arrhythmias. Regular blood tests may be required to check potassium levels.
• Glaucoma or increased intraocular pressure can worsen existing glaucoma or potentially trigger its onset. Its symptoms may include eye pain, blurred vision, and halos around lights.
• Decreased bone density: It can increase the risk of osteoporosis and fractures.
• Adrenal suppression: It is more likely with long-term, high-dose use. It may lead to fatigue, weakness, and reduced ability to handle stress.
• Increased risk of asthma-related death: This risk is thought to be mitigated when used in combination with inhaled corticosteroids.
• Tolerance: The body may become less responsive to the medication over time.
• Increased risk of asthma-related death: Studies have shown a small but significant increase in asthma-related deaths associated with LABA use.

[Note: This list may not cover all possible side effects. Always consult with your healthcare giver for medical advice about side effects.]

Are There Any Warnings for Salmeterol Xinafoate? 

• Call your doctor or seek medical assistance immediately if your or your child’s symptoms do not get better or worsen after using this medication for one week, your short-acting inhaler does not seem to function properly, or you need to use it more often. 
• While you are receiving treatment with this medication, your doctor may ask you to carry a medical identification card (ID) stating that you are using Salmeterol. The card will further state that you may require additional medicine during a serious asthma attack, emergency, or unusual stress. 
• Salmeterol may cause paradoxical bronchospasm, which can make breathing difficult and may be life-threatening. After using this medicine, call your doctor immediately if you experience difficulty breathing, coughing, wheezing, or shortness of breath. 
• Call your doctor immediately if you or your child have a rapid heartbeat, chest pain, nervousness, shaking of feet or hands, a feeling of choking, or tightness or irritation in the throat. 
• While you are using this medication, hypokalemia may also occur. Check with your doctor if you experience any of the following symptoms: dry mouth, decreased urine, convulsions, increased thirst, loss of appetite, weakness, shortness of breath, mood changes, irregular heartbeat, unusual fatigue, muscle cramps or pain, or numbness or tingling in the feet, hands, or lips. 
• This medication can cause an imbalance in your blood sugar levels. Check with your doctor if you or your child have diabetes and notice a change in the tests of your blood or urine sugar. 
• You should not take or stop taking medications without consulting your doctor. 

What Are the FDA Boxed Warnings for Salmeterol Xinafoate?

The FDA boxed warning for salmeterol xinafoate highlights the risk of asthma-related death associated with this medication. Long-acting beta2-adrenergic agonists, including Salmeterol, can increase the risk of asthma-related death when used without inhaled corticosteroids. However, when LABA is used in combination with ICS, data from large scale clinical trials dont show a significant raise in the risk of serious asthma-related events such as hospitalizations, intubations, or death compared to ICS alone. It’s essential to prescribe salmeterol xinafoate only as an additional therapy for patients with inadequately controlled asthma who are already taking an ICS.

What Are the Salmeterol Xinafoate Precautions?

While determining if this medication is safe for you to take, you should weigh its pros and cons. Your doctor will help you decide whether this medication will work best. There are a few factors that you should take into consideration. These are given below:

• Tell your doctor if you have or have ever had an allergy to Salmeterol or any other medications. Also, tell them if you have any other allergic reactions or to any other ingredients present in the medication. Ask your doctor, pharmacist, or healthcare professional for the full list of ingredients. 
• The safety and efficacy of Salmeterol have not been established in children under four years of age. Consult your physician before giving this medication to children. 
• Elderly patients with heart or blood vessel problems may require special caution while taking Salmeterol. 
• You should make regular visits to your doctor to check your or your child’s progress. This will help your doctor to check for any unwanted side effects and ensure that this medication is working properly. 
• Tell your doctor about all the medications you are taking to treat your COPD or asthma. This includes all prescription, non-prescription, and over-the-counter drugs and herbal supplements you are currently taking or planning to take. Your doctor may suggest you stop using Salmeterol and use it only during a serious COPD attack. 
• Let your doctor know if you are currently using or have used MAO inhibitors or TCA for depression within the past 14 days. 

What Are the Contraindications of Salmeterol Xinafoate?

There are certain contraindications of Salmeterol Xinafoate that you should consider before taking this medication. They are as follows:

• Severe hypersensitivity to milk proteins or any component of the drug.
• Primary treatment for status asthmaticus or acute asthma/COPD episodes requiring intensive measures.
• Treatment of asthma without a long-term control medication like an inhaled corticosteroid.

What If You Missed a Dose of Salmeterol Xinafoate?

• If you have missed a dose of Salmeterol Sinafoate, you should take it as soon as you remember. 
• If it is almost time to take your next dose of Salmeterol, you may omit the missed dosage and continue taking your medication as per your regular dosing schedule. 
• Do not take double or extra doses of the same medication to compensate for the missed dose. 
• You can try setting a medicine reminder on your phone to prevent missing medication doses. 

[Note: If you have missed a medication dose and are unsure when to take the next one, immediately consult your doctor or pharmacist.]

What Happens If You Take Too Much of Salmeterol Xinafoate?

You should not take Salmeterol more than prescribed, more frequently, or in large quantities, as it can lead to unwelcome side effects. If you suspect an overdose of Salmeterol Xinafoate, you should seek immediate medical assistance. If someone is having severe symptoms such as difficulty breathing, seizures, or passing out, you can call your doctor, 911, or poison control helpline. You can also head to the nearest emergency room.  

[Note: If you consumed more than the recommended dose, get medical help immediately or call the Poison Help line at 1-800-222-1222.]

How to Store a Salmeterol Xinafoate?

• You should keep Salmeterol in its foil pouch unless you are ready to use it. 
• Store it in a dark, cool, and dry place at a controlled room temperature, away from direct sunlight, moisture, and excess heat. 
• After opening, you should throw away any part you have not used after six weeks or when the indicator signals zero, whichever comes first. 
• You should protect Salmeterol from excess temperature and moisture. 
• Do not keep it in the bathroom. 
• You should keep all medications, including Salmeterol Xinafoate, in a safe place, away from children’s sight and reach. 
• Do not use medications after their expiration date, which is the last day of the month mentioned in the prescription label or carton. 
• Do not keep medications that are outdated or no longer needed. Discard them safely. 
• Unless instructed otherwise, do not flush it down the toilet, pour it into the drain, or throw it in the household garbage bin, as it can cause pollution.
• You should throw the medications in such a way that children, animals, and others cannot consume them.  
• The best way to eliminate unwanted medications is to give them in the medicine take-back program. 
• To learn how to properly discard unwanted medications, consult your pharmacist, healthcare provider, or local waste disposal company. 

[Note: Discuss with your healthcare professional the proper disposal of unused medicine and any questions you may have regarding its storage.]

What Medications Interact with Salmeterol Xinafoate?

It is not advisable to use certain medications together, but some may be used together even if an interaction occurs. When taking Salmeterol, you should let your doctor or healthcare provider know about all the medicines you are taking or planning to take. It is crucial to tell your doctor about the medications listed below. If you are using both medications together, your doctor may want to change your dosage and frequency or monitor your symptoms closely for unwanted side effects. 

• Abametapir
• Acebutolol
• Amphetamine
• Arotinolol
• Atazanavir
• Atenolol
• Befunolol
• Betaxolol
• Bevantolol
• Bisoprolol
• Boceprevir
• Bopindolol
• Bucindolol
• Bupranolol
• Carbamazepine
• Carteolol
• Carvedilol
• Celiprolol
• Ceritinib
• Clarithromycin
• Cobicistat
• Conivaptan
• Darunavir
• Dasabuvir
• Dextroamphetamine
• Dilevalol
• Esmolol
• Fedratinib
• Fexinidazole
• Fosnetupitant
• Idelalisib
• Indinavir
• Itraconazole
• Ketoconazole
• Labetalol
• Landiolol
• Levobunolol
• Lisdexamfetamine
• Lopinavir
• Mavacamten
• Mepindolol
• Methacholine
• Metipranolol
• Metoprolol
• Nadolol
• Nebivolol
• Nefazodone
• Nelfinavir
• Netupitant
• Nilotinib
• Nirmatrelvir
• Omaveloxolone
• Ombitasvir
• Oxprenolol
• Paritaprevir
• Penbutolol
• Phenobarbital
• Pindolol
• Posaconazole
• Practolol
• Primidone
• Propranolol
• Ritonavir
• Saquinavir
• Sotalol
• Talinolol
• Telaprevir
• Telithromycin
• Tertatolol
• Timolol
• Voriconazole

What Are the Other Salmeterol Xinafoate Interactions?

Some medications should not be used around the time of eating certain foods since interactions may occur. Using tobacco or alcohol with such medication may also cause interactions. Discuss with your physician/ healthcare provider the use of your medications with certain foods, alcohol, or tobacco. Certain other medical problems may also affect the use of this medication. Share your complete medical history with your doctor, especially if you have the following conditions: 

• Asthma attack 
• Bronchospasm 
• COPD flare-up
• Diabetes 
• Heart or blood vessel disease 
• Heart rhythm problems 
• Hypertension 
• Hyperthyroidism 
• Hypokalemia 
• Liver disease 
• Ketoacidosis 
• Milk protein allergy 
• Seizures 

[Note: This isn’t a complete list, and there could be other drugs that interact with Salmeterol Xinafoate. Tell your doctor any prescription, over-the-counter medicines, and herbal products you’re taking.]

What Are the Salmeterol Xinafoate Alternatives?

People look for alternative medicines to Salmeterol because it may not suit them or if they are not getting the desired result from the medication. You should consult your doctor, pharmacist, or healthcare provider before changing your brand or dosage. They may help you decide what works best for you. Alternatives of salmeterol xinafoate may include:

Alternative Medications for COPD

• Spiriva (tiotropium)
• Advair Diskus (fluticasone propionate and salmeterol)
• Symbicort (budesonide and formoterol)
• Tudorza Pressair (aclidinium bromide)

Alternative Medications for Asthma

• ProAir HFA (albuterol)
• Singulair (montelukast)
• Pulmicort Flexhaler (budesonide)
• Dulera (mometasone and formoterol)

[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.]

Salmeterol Xinafoate Cost & Coupons

The cost of Salmeterol Xinafoate and options for obtaining it at a lower price is influenced by various factors, including health insurance coverage. Many patients find that their health insurance may not cover medications like Salmeterol Xinafoate for asthma or COPD, leading to significant out-of-pocket expenses- often more than $100 per month. To manage these costs, some patients turn to services like Polar Bear Meds, where they can purchase Salmeterol Xinafoate from Canada at a reduced price. Additionally, customers can use the Salmeterol Xinafoate coupon code WELCOMEPB10 to receive a 10% discount on their first order.

Frequently Asked Questions

How does Salmeterol xinafoate help manage chronic obstructive pulmonary disease (COPD)?

Salmeterol xinafoate helps manage COPD by relaxing the muscles around the airways, making breathing easier. It is a long-acting bronchodilator, relieving symptoms like wheezing and shortness of breath. Its effects typically last 12 hours, making it suitable for twice-daily dosing.

Can salmeterol xinafoate be used for exercise-induced bronchospasm?

Yes, salmeterol xinafoate can be used to prevent exercise-induced bronchospasm. When taken regularly, it helps in controlling symptoms associated with physical exertion by relaxing the bronchial muscles, thus preventing airway constriction during exercise. It’s typically used as a maintenance therapy and not for immediate symptom relief.

What are the potential side effects of long-term use of salmeterol xinafoate?

Long-term use of salmeterol xinafoate may lead to unwanted side effects such as headache, throat irritation, and muscle cramps. In some cases, patients might experience an increased heart rate or palpitations. Using this medication under a doctor’s supervision is important to manage any potential risks effectively.

How does salmeterol xinafoate interact with other asthma medications?

Salmeterol xinafoate is often used in combination with inhaled corticosteroids for better asthma control. It complements the anti-inflammatory effects of corticosteroids by providing bronchodilation. However, it should not be used with other long-acting beta-agonists to avoid the risk of overdose and increased side effects. Always consult a healthcare provider for appropriate medication combination.

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