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What Is a Janumet (Sitagliptin, Metformin) Tablet?
Janumet is a medication that combines two oral medications, metformin, and sitagliptin, which are used to manage diabetes and help regulate blood sugar levels. Metformin functions by reducing the production of glucose (sugar) in the liver and by decreasing the absorption of glucose in the intestines. On the other hand, sitagliptin plays a role in regulating the insulin levels produced by the body after food consumption.
Janumet is prescribed in conjunction with a proper diet and exercise regimen to improve blood sugar control in adults who have type 2 diabetes. It’s important to note that Janumet is not suitable for patients with type 1 diabetes.
Dosage, Usage & Storage of Janumet
The dosage and usage of Janumet (sitagliptin/metformin) can vary depending on individual factors like age, weight, kidney function, and the severity of diabetes. It’s crucial to follow your healthcare provider’s specific instructions. Here are some general guidelines:
Dosage
Janumet is available in different strengths, typically combining different amounts of sitagliptin and metformin. Common strengths include 50/500 mg, 50/1000 mg, 100/1000 mg, etc. These numbers indicate the milligrams of sitagliptin and metformin in each tablet, respectively. Janumet is usually taken twice a day, with meals. Your doctor will specify the exact dosage and timing.
Usage
- It’s recommended to take Janumet with meals to help reduce the risk of stomach upset. This ensures that the medication is absorbed correctly.
- Swallow the tablet whole with a full glass of water. Do not crush, chew, or break it.
- Try to take Janumet at the same time each day to maintain a consistent level of the medication in your body.
- Your healthcare provider will likely monitor your blood sugar levels regularly and may adjust your dosage as needed when you buy Janumet 50 1000.
How to Store?
Store Janumet (sitagliptin/metformin) at room temperature, away from moisture and light. Avoid exposing it to extreme heat or cold. Keep the medication in its original container with the lid tightly closed. Ensure it’s out of reach of children and pets. Do not use Janumet if it’s past its expiration date. If in doubt, consult your pharmacist or healthcare provider before you buy Janumet online.
How Does Janumet Work?
Janumet combines two medications, sitagliptin, and metformin, to manage type 2 diabetes. Sitagliptin increases incretin hormones, which stimulate insulin release and inhibit excess glucose production in the liver. Metformin Hydrochloride reduces liver glucose production and enhances muscle cell sensitivity to insulin. Together, they help regulate blood sugar levels, improve insulin utilization, and decrease excessive glucose production, contributing to more effective diabetes control combined with diet and exercise.
Side Effects of Janumet
Common Side Effects of Janumet may include diarrhea, upset stomach, gas, headache, or weakness. These effects often improve as your body adjusts to the medication. When taken with other diabetes medications that can cause low blood sugar, Janumet may increase the risk. Be aware of symptoms like sweating, shakiness, fast heartbeat, or blurred vision. Although rare, severe allergic reactions to Janumet can occur. Seek immediate medical attention if you experience rash, itching, swelling, severe dizziness, or difficulty breathing.
Other possible side effects are:
- Vitamin B12 Deficiency
- Joint Pain
- Skin Reactions, including Stevens-Johnson syndrome, are also associated with Janumet. Seek immediate medical attention if you notice any skin rash or blisters.
It’s essential to report any unusual or severe side effects to your healthcare provider promptly. Additionally, inform your doctor about any other medications or supplements you are taking, as they can interact with Janumet.
Warnings to Consider
- Metformin can lead to a rare but serious condition called lactic acidosis, particularly in those with kidney or liver issues.
- Before starting Janumet, your doctor will assess your kidney function. This drug may not be suitable for those with impaired kidney function.
- There have been rare reports of pancreatitis in individuals taking Janumet. Seek medical attention if you experience severe abdominal pain.
Janumet-Drug Interactions
Janumet (sitagliptin/metformin) can interact with various medications and substances. Here are some notable interactions:
- Insulin and Insulin-Secreting Agents
- Sulfonylureas
- Beta-Blockers
- Cimetidine
- Certain Diuretics (Thiazides)
- Iodinated Contrast Agents
- Alcohol
- Some medications, such as certain antibiotics or heart medications
Always consult your healthcare provider or pharmacist about potential interactions before starting a new medication, including Janumet. They will be able to provide you with personalized advice based on your specific health situation and when you buy Janumet 50 1000.
Frequently Asked Questions
Can I take Janumet with or without food?
Janumet is typically taken with meals. This helps reduce the risk of stomach upset and ensures the medication is absorbed correctly. It’s important to follow your healthcare provider’s instructions regarding when and how to take Janumet for the best results in managing your blood sugar levels.
Can I crush or cut Janumet in half?
No, Janumet tablets should not be crushed or cut in half. They should be swallowed whole with a full glass of water. Altering the tablet may affect its effectiveness and lead to incorrect dosing. If you have difficulty swallowing, consult your healthcare provider for alternative options.
Can Janumet be used in elderly individuals?
Yes, Janumet can be used in elderly individuals. However, dosage adjustments may be necessary based on factors like kidney function and overall health. Healthcare providers must assess individual circumstances and determine the most appropriate treatment plan for elderly diabetic patients.
Is Janumet available in generic form?
Yes, Janumet is available in generic form. The generic version contains the same active ingredients (sitagliptin and metformin) with the same strengths as the brand-name medication. Generic versions are typically more affordable and can be prescribed by healthcare providers as an alternative to the brand-name product.
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