
Apixaban



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We offer competitive pricing on all our medications. Find a lower price? We'll match it from any verified Canadian online pharmacy! Know More
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Select the prescribed dosage and quantity, then proceed to checkout.
Sign in or create a new account.
Upload your prescription.
Complete your purchase by processing the payment.
Shipping takes approximately 3-5 business days.
Eliquis (apixaban) is a prescription-only anticoagulant (blood thinner) used to prevent and treat serious, potentially life-threatening blood clots. It reduces the ability of blood to form clots, helping lower the risk of stroke in atrial fibrillation and preventing deep vein thrombosis (DVT) or pulmonary embolism (PE).
Eliquis tablets are intended for long-term or short-term use, depending on the condition being treated. Always take Eliquis under the guidance of a licensed healthcare provider. For patients seeking cost savings, licensed pharmacies in Canada may offer competitive pricing and discreet delivery options, helping make treatment more affordable without compromising quality.
| Generic Name | Apixaban |
|---|---|
| Brand Name | Eliquis |
| Drug Class | Factor Xa inhibitor (oral anticoagulant) |
| FDA First Approval | 2012 |
| Prescription Required | Yes, Eliquis is prescription‑only (Rx‑only) |
| Dosage Forms | Oral tablets |
| Strengths | 2.5 mg, 5 mg |
| FDA‑Approved Uses (Indications) | • Reduce risk of stroke & systemic embolism in non‑valvular atrial fibrillation • Treatment of DVT (deep vein thrombosis) • Treatment of PE (pulmonary embolism) • Reduce risk of recurrent DVT & PE after initial therapy • DVT prevention after knee or hip replacement surgery |
| Eliquis Boxed Warning (FDA) | • Spinal/Epidural hematoma risk with neuraxial anesthesia or spinal puncture • Premature discontinuation raises the risk of thrombotic events |
| Common Side Effects (FDA‑listed) | • Bleeding (most common) • Bruising • Anemia |
| Serious Risks | • Major bleeding • Spinal/epidural hematoma |
| Contraindications | • Active pathological bleeding • Severe hypersensitivity to apixaban |
| Storage | • Store these tablets at 20°C to 25°C (68°F-77°F) • Excursions allowed: 15°C to 30°C (59°F-86°F) • Keep in original container; protect from moisture |
| Administration Route | Oral tablet |
| Manufacturer | Bristol‑Myers Squibb / Pfizer |
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“Healthcare providers prescribe Eliquis for its FDA-approved uses:
Below are general Eliquis dosing guidelines. Always follow your healthcare provider’s instructions, as Eliquis doses may be adjusted based on kidney function, age, body weight, or other medications.
| Condition | Typical Starting Dose | Maintenance Dose | Duration |
|---|---|---|---|
| Non‑valvular atrial fibrillation (AFib) | 5 mg orally twice daily | 5 mg twice daily | Ongoing (long‑term) |
| AFib (dose adjustment) | 2.5 mg twice daily | Use if patient has ≥2 of: age ≥80 yrs, weight ≤60 kg, or serum creatinine ≥1.5 mg/dL | Ongoing |
| DVT or PE treatment | 10 mg twice daily for the first 7 days | Then 5 mg twice daily | At least 6 months (as directed) |
| Prevention of recurrent DVT/PE | 2.5 mg orally twice daily | 2.5 mg twice daily | Long‑term (after ≥6 months of treatment) |
| DVT prevention after hip replacement surgery | 2.5 mg orally twice daily | 2.5 mg twice daily | 35 days (start 12-24 hours post‑surgery) |
| DVT prevention after knee replacement surgery | 2.5 mg orally twice daily | 2.5 mg twice daily | 12 days (start 12-24 hours post‑surgery) |
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Eliquis works by blocking Factor Xa, a protein the body uses to form blood clots. When Factor Xa is blocked, the blood is less likely to clot too easily. This helps prevent dangerous clots that can cause a stroke, deep vein thrombosis (DVT), or pulmonary embolism (PE).
By targeting this specific step in the clotting process, Eliquis helps maintain blood flow through the blood vessels. It provides a stable anticoagulant effect without the need for routine blood tests in most people.
Like all medications, Eliquis can cause side effects, although not everyone experiences them.
Eliquis Boxed Warning:
Important Points:
Eliquis (apixaban) should not be taken with certain medications that strongly affect its metabolism or increase bleeding risk.
| Drug Class | Drug Examples |
|---|---|
| Strong CYP3A4/P-gp inhibitors | Ketoconazole, Itraconazole, Ritonavir, Clarithromycin |
| Strong CYP3A4/P-gp inducers | Rifampin, Carbamazepine, Phenytoin, St. John’s Wort |
| Other anticoagulants | Heparin, Enoxaparin, Dabigatran, Rivaroxaban |
| Antiplatelet agents | Aspirin, Clopidogrel, Prasugrel, Ticagrelor |
| NSAIDs | Ibuprofen, Naproxen |
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Here are some Eliquis alternatives you may consider consulting with your doctor:
| Medication | Drug Class |
|---|---|
| Eliquis (apixaban) | Factor Xa inhibitor |
| Xarelto (rivaroxaban) | Factor Xa inhibitor |
| Pradaxa (dabigatran) | Direct thrombin inhibitor |
| Savaysa (edoxaban) | Factor Xa inhibitor |
| Warfarin | Vitamin K antagonist |
| Heparin/LMWH | Injectable anticoagulant |
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Below is an Eliquis head-to-head comparison of mechanisms, dosing, monitoring, renal use, and bleeding risk:
| Attribute | Eliquis (Apixaban) | Pradaxa (Dabigatran) | Xarelto (Rivaroxaban) | Warfarin |
|---|---|---|---|---|
| Mechanism | Factor Xa inhibitor | Direct thrombin (IIa) inhibitor | Factor Xa inhibitor | Vitamin K antagonist (reduces II, VII, IX, X) |
| Typical dosing (NVAF) | 5 mg BID; 2.5 mg BID if dose-reduction criteria met | 150 mg BID; dose adjust in renal impairment | 20 mg QD with food; dose adjust in renal impairment | Individualized dosing; INR 2–3 |
| Routine monitoring | Not required; monitor for bleeding | Not required; monitor for bleeding | Not required; monitor for bleeding | Requires regular INR checks and dose adjustments |
| Renal considerations | Less renal clearance; dose reduction in select patients | Mostly renally cleared; sensitive to kidney function | Dose adjustment needed; higher renal clearance than Eliquis | Not renally cleared; often used in severe renal failure or dialysis |
| Food/diet interactions | No restrictions | Capsules must be swallowed whole | 15-20 mg must be taken with food | Vitamin K intake affects INR; a consistent diet is required |
| Drug interactions | Avoid strong CYP3A4/P-gp inhibitors or inducers | Affected by P-gp inhibitors/inducers | Avoid strong CYP3A4/P-gp inhibitors or inducers | Many interactions via CYP2C9, 1A2, 3A4; multiple prescription/OTC conflicts |
| Bleeding profile | May have lower GI bleeding risk than Pradaxa and Xarelto; lower intracranial bleeding vs Warfarin | Higher GI bleeding risk | Higher GI bleeding risk | Higher risk of intracranial bleeding |
| Administration | Tablets can be crushed or suspended | Capsules must not be opened or crushed | High-dose tablets with food | Multiple strengths; frequent dose changes based on INR |
| Use notes | Often used in older adults, CKD, or high bleeding risk | May be avoided in severe renal impairment | Once-daily convenience; bleeding risk is higher than Eliquis | Often chosen for cost, or severe renal failure; requires monitoring |
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Ordering Eliquis online through a licensed Canadian pharmacy gives you safe, reliable access to your medication at potentially lower costs. Many patients pay up to 90% less than at U.S. pharmacies. New customers may use the Eliquis coupon code WELCOMEPB10 to receive an additional 10% off their first order. To give customers added confidence, we also offer a price-match guarantee, helping ensure you receive the best available price when ordering from Polar Bear Meds.
You can submit your Eliquis prescription easily through your online account after placing your order. A scanned copy or a clear photo of the prescription can be uploaded directly to the website. Additionally, prescriptions may also be sent by email or fax (1-888-804-1287). If a prescription is missing or incomplete, our support team will contact you to help complete the process.
This information is for educational purposes only and does not replace any professional medical advice, diagnosis, or treatment. Always consult a licensed healthcare expert before starting, stopping, or changing Eliquis dosages. Individual results, dosing, and Eliquis side effects may vary.
https://www.webmd.com/drugs/2/drug-163073/eliquis-oral/details
https://www.mayoclinic.org/drugs-supplements/apixaban-oral-route/description/drg-20060729
https://my.clevelandclinic.org/health/drugs/19106-apixaban-tablets
https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/202155s000lbl.pdf
https://www.drugs.com/eliquis.html

Dr. Jackson Miller is a board-certified medicine physician & hospitalist. He is a healthcare professional with a strong background in patient care. With years of experience and a patient-first approach, he believes the foundation of good health is a patient who feels informed and empowered. He contributes to medical content review, drawing on his background in clinical practice and patient education. He focuses on presenting health information in a clear, accurate, and accessible way to help readers make informed decisions. His work emphasizes clarity, evidence-based guidance, and understandable explanations of medical topics.
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