

Fasenra (benralizumab) is a biologic medication approved by the FDA for treating severe eosinophilic asthma in adults and children aged 6 and older. It is administered as a subcutaneous injection, either by a healthcare professional using a prefilled syringe or by the patient using a prefilled autoinjector pen after proper training. Fasenra targets and helps eliminate eosinophils, reducing inflammation in the airways and decreasing asthma flare-ups. Its long-term safety continues to be studied, so it is essential to discuss your health history and any medications you take with your doctor before starting Fasenra. It is not a rescue inhaler and should not be used for sudden asthma attacks. If you plan to buy Fasenra online, be sure to talk to your doctor. They will guide you on the benefits and risks of the medication and help reduce the chance of adverse side effects.
Fasenra (benralizumab) is a monoclonal antibody designed to treat severe eosinophilic asthma in adults and children aged 6 and older. It targets eosinophils — white blood cells that contribute to airway inflammation and asthma flare-ups. By attaching to the interleukin-5 receptor on eosinophils, Fasenra signals the immune system to eliminate these cells, reducing inflammation and the risk of asthma attacks. Beyond asthma, Fasenra is also FDA-approved to treat eosinophilic granulomatosis with polyangiitis (EGPA) in adults and hypereosinophilic syndrome (HES) in patients aged 12 and older.
Fasenra is administered as a subcutaneous injection. It comes in two forms: a prefilled syringe, given by a healthcare professional, and a prefilled autoinjector pen, which patients can use after receiving training from a healthcare provider. For severe asthma, the recommended dosage is one injection every four weeks for the first three doses, followed by one injection every eight weeks. Its long-term safety is still being studied, so it is crucial to discuss your health history and any current medications with your doctor before starting treatment. Fasenra is not intended for use during sudden asthma attacks and should not replace a rescue inhaler.
Important safety information includes avoiding known allergens, using a peak flow meter daily, and considering an annual flu shot to help prevent exacerbations. No formal drug interaction studies have been completed, so always inform your healthcare provider of all medications, herbs, or supplements you are taking. Fasenra must be stored in a refrigerator but can be kept at room temperature for up to 14 days if needed. Proper disposal of unused medication and used autoinjector pens is essential to prevent accidental use and environmental harm. Always follow your doctor's guidance on using and storing Fasenra.
Fasenra (benralizumab) is an FDA-approved biologic used as an add-on maintenance treatment for three conditions:
Fasenra is being studied for other conditions, such as COPD and nasal polyps, but these are not yet FDA-approved.
Important: Fasenra is not a rescue inhaler. It should not be used to treat sudden asthma attacks or a severe episode known as status asthmaticus. Always take it as prescribed, and ask your healthcare provider whether it's right for you.
This medication is available as a solution for subcutaneous injection, meaning it’s injected under the skin. It comes in two forms:
Dosage Information:
The dosage for Fasenra may vary depending on the patient’s age and the severity of the condition. Doctors usually prescribe a starting dose and gradually adjust it as per the individual’s response to the treatment. The following section includes only the average doses of the medication. If you have been prescribed a different dose, do not change it without consulting a medical professional.
Fasenra Dosage for Severe Asthma Management
Fasenra Dosage for Pediatrics
[Note: Remember these recommendations may vary depending on person to person. Discuss it with your doctor, and they’ll customize your dosage accordingly.]
When considering treatment with Fasenra, you must know how to administer the medication properly. Below are some of these steps:
[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They’ll adjust it as needed over time.]
Fasenra targets a specific type of white blood cell known as eosinophils, which play a role in the inflammation associated with asthma. Eosinophils have a protein on their surface called the interleukin-5 receptor. Fasenra works by attaching to this receptor on the eosinophils, signaling the immune system to eliminate them. By reducing the number of eosinophils, the medication decreases inflammation in the airways, which lowers the risk of asthma flare-ups.
Within just 24 hours of administration, Fasenra can remove nearly all eosinophils from the bloodstream. However, treating severe eosinophilic asthma effectively usually takes more time, and improvements in the condition are gradual. It is important to continue taking Fasenra to maintain control over asthma and reduce the likelihood of flare-ups.
Common Side Effects of Fasenra: Before you use Fasenra for eosinophilic asthma, you must know that the medication can cause several side effects. These reactions are generally common and do not require immediate medical attention, as they subside within a few days or weeks. However, if they persist for more than the mentioned period or worsen, contact your medical professional. Some of these common side effects may include:
Serious Side Effects of Fasenra: Benralizumab, one of the active ingredients of Fasenr, can cause adverse reactions. If these side effects are left overlooked, they result in life-threatening situations. So, when considering treatment with Fasenra, be mindful of any unusual symptoms. Some of these side effects may include:
[Note: Remember, this list may not cover all possible side effects. Always consult with your healthcare giver for medical advice about side effects.]
Before you plan to buy Fasenra online, discuss your health history with your doctor, as this medication may not be suitable for you if you have certain medical conditions or other health factors. These warnings are as follows:
When considering treatment with Fasenra for eosinophilic asthma, you must be aware of the below precautions, as following these preventive measures can reduce the risk of potential side effects:
This medication is contraindicated in the following conditions:
[Note: If you have missed a dose of your medication and are unsure about when to take the next one, immediately consult your doctor or pharmacist.]
Don’t use more Fasenra than your doctor recommends. If you think you have taken too much Fasenra, call your doctor immediately. For guidance, you can also contact America’s Poison Centers at 800-222-1222 or use their online tool. If your symptoms are severe, call 911 or go to the nearest emergency center immediately.
[Note: If you consumed more than the recommended dose, get medical help right away or call the Poison Help line at 1-800-222-1222.]
Proper storage is crucial to maintaining the long-term effectiveness of any medication. If you plan to buy Fasenra from Canada, follow the below storage guidelines:
[Note: Discuss with your healthcare professional about the proper disposal of any unused medicine and any questions you may have regarding its storage.]
Currently, there are no known interactions between Fasenra and any drugs, herbs, foods, or supplements. However, it is still important to be cautious and informed. Before starting Fasenra for severe asthma management, discuss all the medications you are taking with your doctor or pharmacist. This includes over-the-counter and prescription drugs, as well as vitamins, herbs, and supplements. Sharing this information helps your healthcare provider ensure that there are no potential interactions that could affect your treatment. If you have any questions or concerns about possible drug interactions, do not hesitate to ask your doctor or pharmacist. They can provide you with the most accurate and personalized advice.
[Note: This isn’t a complete list, and there could be other drugs that interact with Fasenra. Make sure to tell your doctor about any prescription, over-the-counter medicines, and herbal products you’re taking.]
Drug alternatives offer a convenient way for patients to switch their treatment options from one to another. This choice is influenced by many factors, including the lack of suitability due to an existing medical condition. While many popular drugs are available in the market, patients are advised not to take any medicine without consulting their doctor. The medical professional will examine your condition and determine the best medication for you. Here are some drugs that you can take in place of Fasenra:
[Note: Your doctor will choose what's best for you. Don't use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.]
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Dr. Jackson Miller is a board-certified medicine physician & hospitalist. He is a healthcare professional with a strong background in patient care. With years of experience and a patient-first approach, he believes the foundation of good health is a patient who feels informed and empowered. He contributes to medical content review, drawing on his background in clinical practice and patient education. He focuses on presenting health information in a clear, accurate, and accessible way to help readers make informed decisions. His work emphasizes clarity, evidence-based guidance, and understandable explanations of medical topics.
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