Levalbuterol Tartrate

Levosalbutamol

Levosalbutamol, often known as Levalbuterol, is an FDA-approved medication for the treatment of breathing problems such as asthma & chronic obstructive pulmonary disease (COPD). This quick-relief drug helps prevent lung problems, including wheezing and shortness of breath. It is a short-acting bronchodilator that functions by relaxing the muscles present in the airways, thus increasing the airflow to the lungs. Children and adults can use this medication, but their dosage may vary depending on various factors, including the severity of the condition and the body needs of each patient. Therefore, it is advisable to follow the dosing schedule provided by your healthcare provider.

Levosalbutamol Overview

Levosalbutamol, also known as Levalbuterol, is a prescription medication widely used to treat respiratory conditions like asthma and chronic obstructive pulmonary disease (COPD). Its active ingredient is Levalbuterol, a selective beta2-adrenergic receptor agonist. This inhaler effectively relaxes the muscles in the airways to improve breathing. Levosalbutamol is FDA-approved, ensuring its efficacy and safety for prescribed use.

Levalbuterol is available in inhalation solution and aerosol, each with distinct strengths. To use the inhaler, shake it well before each spray and inhale the prescribed number of puffs, usually every 4 to 6 hours as needed. This medication is suitable for adults, but for children, it has different dosage recommendations based on their age groups and the specific form of the medication. It works by stimulating beta2-adrenergic receptors in the lungs, leading to muscle relaxation and airway dilation, which eases breathing difficulties.

While effective in use, it has specific side effects, which may include tremors, nervousness, headache, and dizziness. To minimize risks, follow the prescribed dosage and schedule. If a dose is missed, take it as soon as possible unless it is nearly time for the next dose; do not double the dose. In case of an overdose, get medical attention right away. Store the inhaler or your medication at room temperature, away from sunlight and heat, and keep it out of reach of children.

What Are the Uses of Levosalbutamol?

Levosalbutamol is used to prevent lung problems caused by conditions like asthma and COPD. These problems are as follows:

• Wheezing
• Shortness of breath
• Coughing
• Chest tightness

What Are the Forms & Strengths of Levosalbutamol?

This medication is available in the following forms and strengths:

Nebulizer Solution

• 0.31mg/3mL
• 0.63mg/3mL
• 1.25mg/3mL
• 1.25mg/0.5mL

Aerosol

• 45mcg/actuation

What Are the Recommended Dosages of Levosalbutamol?

Adult Dosage for COPD

• Inhalation Aerosol: Take two inhalations of 90 mcg orally every 4 to 6 hours or one inhalation of 45 mcg orally every 4 hours. 
• Inhalation Solution: The usual recommended dosage of Levosalbutamol is 0.63 mg. It should be administered orally by nebulization thrice daily, every 6 to 8 hours. Moreover, patients with severe asthma or who are not responding to the initial dose should inhale 1.25 mg orally by nebulization thrice daily.

Adult Dosage for Asthma

• Inhalation Aerosol: Take two inhalations of 90 mcg orally every 4 to 6 hours or one inhalation of 45 mcg orally every 4 hours. 
• Inhalation Solution: The usual recommended dosage of Levosalbutamol is 0.63 mg. It should be administered orally by nebulization thrice daily, every 6 to 8 hours. Moreover, patients with severe asthma or who are not responding to the initial dose should inhale 1.25 mg orally by nebulization thrice daily.

Children’s Dosage for COPD

• Inhalation Aerosol: This medication is not recommended for children below 4 years of age. If the children are 4 years or older, they should be given two inhalations of 90 mcg administered orally every 4 to 6 hours or one inhalation of 45 mcg every 4 hours.
• Inhalation Solution: This medication is not recommended for children below 6 years of age. If the children are within the age group of:
  • 6 to 11 Years: The usual dosage is 0.31 mg, administered orally by nebulization thrice a day. Remember, the dosage should not exceed the maximum dose of 0.63 mg inhaled orally thrice a day.
  • 12 Years or Above: The recommended dosage is 0.63 mg, administered orally by nebulization thrice a day. Moreover, children with severe asthma or who are not responding to the initial dose should be given 1.25 mg orally by nebulization thrice daily.

Children’s Dosage for Asthma

• Inhalation Aerosol: This medication is not recommended for children below 4 years of age. If the children are 4 years or older, they should be given two oral inhalations of 90 mcg every 4 to 6 hours or one inhalation of 45 mcg every 4 hours.
• Inhalation Solution: This medication is not recommended for children below 6 years of age. If the children are within the age group of:
  • 6 to 11 Years: The typical dosage range is 0.31 mg, administered orally by nebulization thrice a day. Remember, the dosage should not exceed the maximum dose of 0.63 mg inhaled orally thrice a day.
  • 12 Years or Above: The recommended dosage is 0.63 mg, administered orally by nebulization thrice a day. Moreover, children with severe asthma or who are not responding to the initial dose should be given 1.25 mg orally by nebulization thrice daily.

[Note: Remember, these recommendations may vary from person to person. Discuss it with your doctor, and they’ll customize your dosage accordingly.]

How to Use Levosalbutamol? 

• Before jumping to the basic administration steps, read all the instructions carefully mentioned in the patient information leaflet. 
• Follow the dosage instructions exactly as instructed by your medical provider to avoid any complications.
• An adult should supervise any child using this inhalation medication.
• Before using the inhaler, make sure to prime the device when using it first time. Pump the fours sprays into the air but away from your face. You must prime the inhaler if it has not been used for over three days.

If it is an inhaler:

• Shake the container well before each use.
• Remove the inhaler mouthpiece and breathe out completely. Then, put the mouthpiece into your mouth and close your lips. Now, breathe in slowly, but remember to push the canister down while breathing. 
• Hold your breath for ten seconds and breathe out steadily.
• If you are inhaling more than one time, keep a 1-minute gap between each inhalation and make sure to shake the inhaler again for a second puff.
• Once you are done with the whole process, dry clean the device and store it with a cap on the mouthpiece. 
• Clean your inhaler weekly by taking out the canister and rinsing the mouthpiece under warm running water for at least 30 seconds. Shake off the excess water and let the components air dry thoroughly before reassembling the inhaler.

If it is a solution:

• Levalbuterol solution comes with a nebulizer. Before using it, mix the concentrate with a liquid. You can ask your pharmacist for the liquid selection. 
• To use the solution with a nebulizer, you need to open the package and pour the medicine into the nebulizer chamber. Use the medicine that is prescribed to you, not more or less of it.
• Now, connect the mask with the compressor’s drug chamber.
• Sit in an upright position comfortably and place the mask, covering your mouth and nose.
• Turn the compressor on.
• Inhale the mist slowly until the drug chamber is empty.
• Clean your device after each use, following the instructions that came with the nebulizer.
• Use the plastic vial only once. Throw away the medication after one use, even if only a few drops are left in it.

[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They’ll adjust it as needed over time.]

How Does Levosalbutamol Work?

Levosalbutamol works by stimulating beta2-adrenergic receptors in the lungs, which relaxes the airways’ muscles. This relaxation helps to expand the airways, making it easier to breathe. It is particularly effective in treating conditions like asthma & chronic obstructive pulmonary disease (COPD), where airway contraction causes breathing difficulties. By quickly improving airflow, the Levosalbutamol inhaler provides relief from symptoms like wheezing, shortness of breath, and chest tightness.

Important Safety Information for Using Levosalbutamol

What Are the Side Effects of Levosalbutamol?

Levosalbutamol can cause certain side effects, which are usually temporary. Depending on their severity, these side effects last from a few days to weeks. If these side effects persist more than the mentioned period or become intense, talk to a medical expert right away. Here are some of the common side effects of Levosalbutamol:

• Rapid heartbeats
• Dizziness
• Headache
• Tremors
• Trouble sleeping
• Runny nose
• Sore throat
• Nervousness
• Chest tightness
• Vomiting
• Dry mouth
• Coughing
• Accidental injury
• Bronchitis 

Levosalbutamol may also cause certain serious side effects, which can be life-threatening if not taken prompt action. If you are experiencing any unusual or serious side effects while taking your medication, contact a medical practitioner right away. Some of the serious side effects of Levosalbutamol may include:

• Severe skin rash
• Itching on the skin
• Hives
• Swelling of the face, throat, tongue or lips
• Irregular heart rhythm 
• Chest pain
• High blood pressure
• Low potassium levels
• Wheezing or trouble breathing that becomes worse after each use.
• Choking
• Constipation
• Confusion
• Severe allergic reactions

[Note: Remember, this list may not cover all possible side effects. Always consult with your healthcare giver for medical advice about side effects.]

Are There Any Warnings for Levosalbutamol? 

Before using this medication, beware of the following warnings:

• Paradoxical Bronchospasm: Levosalbutamol can cause paradoxical bronchospasm, which may be life-threatening. If this occurs, stop using the medication immediately and seek alternative treatment. This typically happens with the first use of a new canister.
• Deterioration of Asthma: Asthma may worsen suddenly over hours or gradually over days. If a patient needs more doses of Levosalbutamol than the prescribed one, this is a sign of asthma destabilization and requires reevaluation of the patient’s treatment, possibly adding anti-inflammatory medication like corticosteroids.
• Use of Anti-Inflammatory Agents: Using a beta-adrenergic agonist like Levosalbutamol alone may not control asthma in many patients. Consider adding anti-inflammatory agents, such as corticosteroids, to the treatment plan early on. 
• Cardiovascular Effects: Beta-adrenergic agonists, including Levosalbutamol, can cause significant cardiovascular effects, which may consist of changes in heart rate, blood pressure & ECG readings. Although these symptoms are very rare to occur after administration of Levosalbutamol, if they appear, discontinue using this medication. Patients with cardiovascular disorders like coronary insufficiency, arrhythmias, and hypertension should be cautious while using this medication.
• Do Not Exceed Recommended Dose: Excessive use of inhaled sympathomimetic drugs can be fatal in asthma patients. The exact cause of death is unclear but may involve cardiac arrest following severe asthma attacks and hypoxia.
• Coexisting Conditions: Patients using beta-adrenergic bronchodilators like Levosalbutamol have reported systolic and diastolic blood pressure changes. Therefore, this medication should be used with caution in patients who have cardiovascular disorders, convulsive disorders, hyperthyroidism, diabetes mellitus, or those highly responsive to sympathomimetic amines. 
• Hypokalemia: Levosalbutamol may cause significant hypokalemia in some patients, potentially leading to adverse cardiovascular effects. This effect is usually temporary and does not require supplementation.

What Are the FDA Boxed Warning for Levosalbutamol?

Black box or boxed warnings are the most serious warnings issued by the FDA for a particular drug. These warnings alert doctors and patients about the medication’s harmful effects, which can be life-threatening. Levosalbutamol did not receive any such warnings from the FDA.

What Are the Levosalbutamol Precautions?

While using Levosalbutamol, patients should be aware of the following precautions:

• If you are considering using this medication for your lung problems, tell your medical provider about your allergies if you are allergic to any of the medication’s ingredients or similar drugs like albuterol and metaproterenol. This product may contain certain inactive components that can cause allergic reactions.
• Before using this medication, inform the medical professional about the medical history, especially of diabetes, kidney problems, seizures, high blood pressure, or heart problems.
• Avoid consuming alcohol or marijuana while taking this medication, as Levosalbutamol can make you dizzy. Intaking such substances may worsen the side effects. So, it is advised not to drive or use machines requiring alertness.
• If you are taking an inhalation solution, avoid using the nebulizer solution if it seems colorless or unclear.
• Do not use too much medication too often, as it can result in adverse side effects, which can be life-threatening. Get medical assistance if the medication is not working properly.
• If you are undergoing surgery or any medical procedure, inform your medical expert or dentist about the products you use. This includes all prescription drugs, nonprescription drugs, and herbal products.
• If you are pregnant or planning to have a baby, use this medication when needed urgently. Consult with a medical professional first and discuss every risk and benefit with them to avoid harming the unborn baby.
• It is not clear whether the drug enters breast milk or not. So, if you are taking this medication or considering using it, talk to a medical expert.

What Are the Contraindications of Levosalbutamol? 

This medication is not recommended for patients with active hypersensitivity or a history of hypersensitivity to Levosalbutamol, any ingredients used in its formulation, or racemic albuterol. If you have used this medication with such condition, you may experience adverse allergic reactions, which may include:

• Rash
• Bronchospasm
• Anaphylaxis
• Oropharyngeal edema
• Urticaria
• Angioedema

What If You Missed a Dose of Levosalbutamol?

Generally, patients are advised not to miss any dose of their medication, but if you have skipped your medication, you can:

• Take the missed dose as soon as possible or whenever you remember.
• If it is almost time for the next dose, you can skip the missed dose and continue following your usual dosing schedule.
• Remember not to take double doses to make up for the missed dose. Doing so can lead to serious complications.
• Use Levosalbutamol inhalation regularly for effective results.
• Use medication apps or set reminders on your phone to avoid skipping any doses. 
• If you are still unsure about the missed medicines, you can ask a medical professional. They will suggest alternate options.

[Note: If you have missed a dose of your medication and are unsure about when to take the next one, immediately consult your doctor or pharmacist.]

What Happens If You Take Too Much of Levosalbutamol?

Overdosing on Levosalbutamol can cause serious symptoms due to too much beta-adrenergic stimulation. These symptoms may include:

• Seizures
• Chest pain
• High or low blood pressure
• Rapid heartbeat (up to 200 beats/minute)
• Irregular heartbeats
• Nervousness
• Headache
• Tremors
• Dry mouth
• Palpitations
• Nausea
• Dizziness
• Fatigue
• General discomfort, and 
• Trouble sleeping 
• Low potassium levels 
• Severe misuse can lead to cardiac arrest and even death 

If you are experiencing any of the above overdose symptoms, get medical help by calling 911. Doctors may use a cardioselective beta-blocker since it can cause bronchospasm. Moreover, there is not enough evidence to know if dialysis helps in case of an overdose.

[Note: If you consumed more than the recommended dose, get medical help right away or call the Poison Help line at 1-800-222-1222.]

How to Store a Levosalbutamol?

• Keep your Levosalbutamol inhaler at 20° to 25°C. Store it with the mouthpiece facing downwards. 
• Avoid keeping the device in heat or direct sunlight.
• Do not refrigerate the inhaler.
• If your device has a number indicator on it and shows ‘0’, you can throw it as it indicates that all sprays have been used.
• Do not keep your inhaler near an open flame or high heat, such as in a car. Overheating can cause the canister to explode. 
• Once your inhaler is no longer useful, throw it away properly. Do not try to puncture or burn the empty canister. 
• Keep the device out of reach and sight of children and pets.
• Ask a medical professional or pharmacist how to dispose of the inhaler carefully without damaging the environment.
• Do not flush it down the toilet.

[Note: Discuss with your healthcare professional about the proper disposal of any unused medicine and any questions you may have regarding its storage.]

What Medications Interact with Levosalbutamol?

Levosalbutamol can interact with different medications, which can cause harmful reactions in your body. These interactions can happen in two ways. They can either reduce the effectiveness of the drug by disturbing its functioning or increase the risk of side effects. Below is the list of drugs that can interact with Levosalbutamol. Remember, this list does not contain every drug.

• Carteolol
• Carteolol ophthalmic
• Carvedilol
• Ceritinib
• Cocaine nasal
• Cocaine topical
• Labetalol
• Levobunolol ophthalmic
• Metipranolol ophthalmic
• Metolazone
• Nadolol
• Ozanimod
• Papaverine
• Penbutolol
• Propranolol
• Pindolol
• Ribociclib
• Sotalol
• Timolol
• Timolol ophthalmic
• Ziprasidone
• Xylometazoline nasal
• Voclosporin
• Voriconazole
• Quetiapine
• Quinidine
• Ketamine
• Ketoconazole
• Isoniazid
• Isoproterenol
• Albuterol
• Benzthiazide
• Doxepin
• Entrectinib
• Flutamide
• Gemifloxacin
• Hydrocortisone
• Isoniazid

What Are the Other Levosalbutamol Interactions?

Besides drug interaction, Levosalbutamol also has certain alcohol, food, and disease interactions:

• Caffeine
• Cardiovascular
• Diabetes
• Hypokalemia
• Seizures
• Renal dysfunction

[Note: This isn’t a complete list, and there could be other drugs that interact with Levosalbutamol. Make sure to tell your doctor about any prescription, over-the-counter medicines, and herbal products you’re taking.]

What Are the Levosalbutamol Alternatives?

Some of the alternatives to Levosalbutamol are:

• Breztri Aerosphere
• Symbicort
• Prednisone
• Trelegy Ellipta
• Montelukast
• Anoro Ellipta
• Budesonide/formoterol /glycopyrrolate
• Breo Ellipta
• Spiriva
• Albuterol
• Advair Diskus
• Combivent

[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.]

Levosalbutamol Cost & Coupons

Levosalbutamol cost can be influenced by various other factors, such as health insurance, location, and pharmacy from which you buy. While it is an FDA-approved medication, it can be quite expensive for some people to buy. Health insurance can manage this cost, but not every insurance plan covers all drugs. Therefore, if you are searching for online sources to buy Levosalbutamol inhalers at affordable prices without any insurance coverage, reach out to Polar Bear Meds. Additionally, customers can use the Levosalbutamol coupon code WELCOMEPB10 for more discounted rates to receive a 10% discount on their first order.

Frequently Asked Questions

Can I take Levosalbutamol if I have a seizure disorder?

If you have a condition like seizure disorder, it is crucial to consult your doctor before taking Levosalbutamol, as this medication may lead to central nervous system stimulation. Therefore, take medical assistance first; the experts will evaluate every risk and benefit and may adjust your treatment plan accordingly. Always disclose your complete medical history to your medical provider to determine the best possible care and avoid complications.

What happens if I do not prime my Levosalbutamol inhaler?

Prime means to spray the solution into the air before using it. So, if you do not prime your Levosalbutamol inhaler, it may not deliver the correct dose of medication. Priming ensures the inhaler is ready for use, providing an accurate dose with each puff. Without priming, the first few doses may be insufficient, reducing the effectiveness of the treatment. To prime the inhaler, follow the manufacturer’s instructions, which typically involve shaking the inhaler and releasing a few test sprays into the air.

Can I drink alcohol during my treatment with Levosalbutamal?

It is best recommended to avoid consuming alcohol while using Levosalbutamol. Alcohol can also raise the risk of side effects, including dizziness and headache. It can also interfere with the effectiveness of the medication. Combining alcohol while taking this medication might exacerbate respiratory issues or other side effects. Consult your physician for personalized advice regarding alcohol consumption during your treatment, as they can provide guidance based on your particular health condition and treatment plan.

For how long do I have to use the Levosalbutamol inhaler?

The duration of Levosalbutamol inhaler use depends on your condition and your doctor’s recommendations. Some patients may need it for short-term relief during an acute asthma attack, while others might require long-term use for managing chronic conditions like asthma or COPD. Always follow your healthcare provider’s instructions regarding the duration of use. Regular check-ups are also essential to reassess your condition and adjust the treatment plan as necessary to ensure optimal control of your symptoms.

Can I take my Levosalbutamol inhaler while traveling?

Yes, you can take your Levosalbutamol inhaler while traveling. Ensure it is stored properly, away from extreme temperatures, and keep it within easy reach, especially during flights or long journeys. Carry a spare inhaler and your prescription in case of emergencies or delays. Check your travel regulations to see whether you are allowed to carry medications and carry a doctor’s note if necessary. This ensures you have continuous access to your medication and can manage your respiratory condition effectively while on the move.

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