Edoxaban

Buy Lixiana Online

Lixiana is a prescription medication used to treat and prevent blood clots. Its active ingredient is edoxaban, a direct factor Xa inhibitor. It is available in the form of a tablet with strengths of 15 mg, 30 mg, and 60 mg, to be taken once daily, orally by mouth, with or without food. It works by inhibiting factor Xa, an enzyme crucial in blood clotting, effectively reducing clotting formation. For personalized guidance and advice for the safe and efficient use of the medication, you should consult a licensed healthcare professional. You can buy Lixiana (edoxaban) online at affordable prices from reputable sources. 

Product Overview

Lixiana, containing the active ingredient edoxaban, is a potent anticoagulant used to prevent and treat blood clots. Edoxaban is a direct factor Xa inhibitor, meaning it selectively blocks factor Xa, an enzyme crucial in the blood clotting process. By inhibiting this enzyme, Lixiana effectively reduces the formation of blood clots.

Available in strengths of 15, 30, and 60 mg, Lixiana is typically taken orally once daily, with or without food. This simple dosing regimen enhances patient adherence to treatment. Lixiana is suitable for adults who require anticoagulation for conditions such as atrial fibrillation or venous thromboembolism. It provides reliable anticoagulation without the need for routine blood monitoring, offering a convenient alternative to traditional medications like warfarin.

Common side effects of Lixiana include bleeding complications, which can range from minor to severe. Patients should be carefully monitored for signs & symptoms of bleeding & seek immediate medical attention if they experience unusual bleeding or bruising. It is crucial to inform medical providers about any other medications being taken, as drug interactions can affect the efficacy and safety of Lixiana. In case of a missed dose, take it as soon as remembered unless it is nearly time for the next dose. Do not double up doses. Overdose may lead to excessive bleeding; seek emergency help if this occurs.

What Are the Uses of Lixiana?

It is used in adults for:

• Preventing stroke and systemic embolism 
• Deep vein thrombosis and pulmonary embolism

What Are the Forms & Strengths of Lixiana?

Lixiana is available in the form of an oral tablet with the following strengths:

• 15 mg
• 30 mg
• 60 mg

What Are the Recommended Dosage of Lixiana?

For Atrial Fibrillation

• 60 mg once daily to be taken by mouth. 

For Deep Vein Thrombosis

• 60 mg taken once daily following five to ten days of initial therapy with parenteral anticoagulant therapy. 

For Pulmonary Embolism

• 60 mg to be taken orally once daily following five to ten days of initial therapy with a parental anticoagulant. 

[Note: These recommendations may vary from person to person. Discuss them with your doctor; they’ll customize your dosage accordingly.]

How to Use Lixiana?

• Before taking this medication, carefully read and follow the directions for use that came along with this prescription. If you have any questions or concerns or do not understand any part of the leaflet, ask your doctor or pharmacist. 
• Use Lixiana exactly as prescribed by your doctor. Do not use more or less of it, in large quantities or for longer than prescribed. 
• This medication is available as tablets, which can only be obtained with a prescription.
• To prevent the first stroke in patients with atrial fibrillation, the recommended dosage is 60 mg, taken orally by mouth once every day. 
• Swallow the tablet as a whole with a full glass of water. Do not break, crush, or chew it. 
• If you have difficulty swallowing the tablets as a whole, you should discuss other ways of taking this medication. Your doctor may recommend crushing and breaking the tablets and mixing them with water or apple juice immediately before swallowing them. Your doctor may also give you the crushed tablets through a tube in the nose or stomach. 
• This medication may be taken with or without food, but it is best recommended to take it around the same time every day. 
• You should not stop taking this medication abruptly without consulting a licensed healthcare professional, as it can lead to unwanted health problems caused by blood clots. 

[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They’ll adjust it as needed over time.]

How Does Lixiana Work?

Lixiana, also known by its generic name edoxaban, is an anticoagulant medication that belongs to a class of drugs known as direct factor Xa inhibitors. It works by selectively blocking the action of factor Xa which is a critical enzyme in the blood clotting cascade. By inhibiting factor Xa, Lixiana effectively reduces the body’s ability to form blood clots. This mechanism of action interrupts both the intrinsic and extrinsic pathways of coagulation, leading to a decreased production of thrombin and, consequently, less fibrin formation. 

Important Safety Information for Using Lixiana

What Are the Side Effects of Lixiana?

Common Side Effects of Lixiana: 

Like other medications, Lixiana may cause side effects in some people. It is important to note that not everyone using this medication will experience side effects while using this medication. Most of the side effects caused by Lixiana are not serious and disappear within a few days or weeks as your body adjusts to the medication. Common side effects caused by Lixiana may include:

• Bleeding (various types)
• Anemia
• Nausea
• Rash

Mild Side Effects of Lixiana: 

Mild side effects caused by Lixiana do not usually require medical attention and disappear on their own within a few days or weeks as your body adjusts to the medication. 

• Dizziness
• Headache
• Abdominal pain
• Fatigue
• Abnormal liver function tests

Serious Side Effects of Lixiana: 

In certain rare cases, Lixiana may cause serious side effects in some people. Severe side effects require prompt medical attention and can be life-threatening if not treated promptly. You should report any new or worsening symptoms to your healthcare provider. If you are concerned about side effects caused by this medication or want to learn about how to prevent and manage side effects caused by this medication, consult a licensed healthcare provider. Serious side effects caused by Lixiana may include:

• Major bleeding events may lead to hospitalization, transfusions, or even be life-threatening in severe cases.
• Spinal/epidural hematoma. Its symptoms may include back pain, numbness, muscle weakness, or incontinence.
• Increased risk of thrombotic events if discontinued abruptly
• Severe allergic reactions. Its symptoms may include difficulty breathing, swelling of the face/throat, and severe rash.
• Liver injury
• Increased bleeding risk in specific populations such as elderly patients, patients with renal impairment, or individuals with low body weight may be at higher risk.

[Note: This list may not cover all possible side effects. Always consult with your healthcare provider for medical advice about side effects.]

Are There Any Warnings for Lixiana? 

• Lixiana is designed to reduce dangerous clotting, but it can also increase the risk of serious and potentially fatal bleeding. Contact your doctor immediately if you experience more frequent bruising, difficulty stopping bleeding from cuts, or more frequent nosebleeds. Seek urgent medical help if you experience stomach bleeding symptoms, such as passing blood in the stool, vomiting that looks like coffee, or coughing up blood.
• If you have decreased renal function or kidney disease, Lixiana may accumulate in your body, raising the risk of side effects. Discuss with your doctor how this medication might impact your kidney condition, whether dosage adjustments are necessary, and if any special monitoring is required.
• The safety and efficacy of Lixiana in patients with severe liver impairment have not been established. For those with liver dysfunction or liver disease, it is essential to consult with your doctor regarding how this medication may affect your liver condition, dosing adjustments, and the need for specific monitoring. Lixiana is not recommended for individuals with severe liver dysfunction.
• Lixiana should not be taken by individuals with spinal or epidural catheters in place or within 5 hours of their removal. It is also not recommended for those receiving pain medication through an epidural catheter.
• Do not discontinue Lixiana without consulting your doctor. Premature cessation of Lixiana increases the risk of severe blood clots.
• If you plan to have surgery, including a dental procedure, tell your doctor, dentist, or surgeon about all your medications, including Lixiana. Your doctor may advise stopping the medication temporarily to minimize the risk of extreme bleeding during surgery and delayed healing afterward.
• It is unknown if Lixiana passes into breast milk. If you are breastfeeding, discuss with your doctor whether you should continue taking Lixiana and the potential impact on your baby. 
• Lixiana should only be used during pregnancy if the potential benefits justify the risks. If you get pregnant while taking this medication, contact your doctor immediately.

What Are the FDA Boxed Warning for Lixiana?

A boxed warning for Lixiana (edoxaban) has been issued by the FDA due to certain risks associated with its use. 

• Decreased Effectiveness in People with Atrial Fibrillation & Good Kidney Function: Before starting Lixiana, your doctor will test your kidney function with a creatinine clearance (CrCl) test. If your kidneys work very well (CrCl greater than 95 mL/min) and you have atrial fibrillation, Lixiana might not be effective in preventing strokes.
• Warning for Stopping Treatment Early: Do not stop taking Lixiana without consulting your doctor. Stopping it too soon increases the risk of blood clots, which can cause a stroke. Your doctor might stop the medication temporarily before surgery or a medical/dental procedure and will tell you when to start it again. If you must stop taking Lixiana, your doctor might prescribe another medication to prevent blood clots.
• Risk of Spinal or Epidural Blood Clots (Hematomas): Lixiana can increase the risk of serious blood clots in the spine, which can cause permanent paralysis. You are at higher risk if you have an epidural catheter, take NSAIDs or other blood thinners, have had spinal surgery, or have spine problems. Your physician will monitor you carefully if you have any of these risk factors. Inform your doctor immediately if you experience tingling or numbness in your legs and feet, incontinence, back pain, or muscle weakness in your legs and feet.

What Are the Lixiana Precautions?

• Before you start taking Lixiana, you should share your complete medical history with your doctor. Especially if you have the following conditions:
  • Stomach ulcer or recent stroke
  • Have a liver disease that slo affects your clotting ability
  • Pregnant 
  • Breastfeeding 
  • Currently experiencing severe or dangerous bleeding. 
  • Are taking certain medications to reduce the risk of bleeding, such as warfarin, apixaban, dabigatran, and heparin. 
• Before taking this medication, tell your doctor if you have an allergy to it, edoxaban, or any other medications. Also, tell your doctor if you have an allergy to any of the ingredients present in the product. Ask your doctor or pharmacist for the full list of ingredients. 
• It is crucial that you visit your doctor on a regular basis while using this medication to ensure that it is working properly and to determine whether you should continue taking it. Your doctor may also recommend that you take certain tests, such as blood & urine tests, to check for unwanted side effects. 
• Do not take other medications without consulting your doctor. 
• Contact your physician immediately if you have unusual bruising, bleeding, abnormal vaginal bleeding, tarry, black stools, headache, dizziness, swelling, or unusual nosebleeds. These may be signs of bleeding problems.  
• This medication may increase your risk of forming blood clots in the epidural area or spine, which may cause long-term or permanent paralysis. 

What Are the Contraindications of Lixiana?

Lixiana is contraindicated for use in patients who have/are:

• A hypersensitivity to Lixiana or any of the ingredients in the medication. 
• Existing severe or existing bleeding
• Taking certain medications, such as apixaban, heparin, dabigatran, warfarin, tinzaparin, and enoxaparin, reduces the risk of clotting.  
• Have a condition that increases the risk of experiencing dangerous or severe bleeding, such as a stomach ulcer or stroke. 
• Have liver disease that affects clotting ability
• Pregnant or suspected pregnancy
• Breast-feeding 

What If You Missed a Dose of Lixiana?

• If you have missed a dose of Lixiana, you should take it as soon as you remember and return to your regular medication dosage schedule. 
• However, if it is almost time to take your next dose, you may omit the missed dose and continue taking your medication according to your regular dosing schedule. 
• Do not take double or extra doses of the same medication to compensate for the missed dose, as it can cause undesirable side effects. 
• You can set a reminder on your phone to prevent missed doses further.

[Note: If you have missed a medication dose and are still determining when to take the next one, consult your doctor or pharmacist immediately.]

What Happens If You Take Too Much of Lixiana?

Lixiana overdose may lead to hemorrhage. If you suspect an overdose, you should immediately call your doctor, 911, or the poison control helpline. You can also head to the nearest emergency room. 

[Note: If you consumed more than the recommended dose, get medical help immediately or call the Poison Help line at 1-800-222-1222.]

How to Store a Lixiana?

• You should store Lixiana tablets in their original container, tightly closed away from excess heat, direct sunlight, and moisture. 
• Do not keep it in the bathroom or near the sink. 
• Keep all medications, including Lixiana, in a safe place, away from the sight and reach of children and pets. 
• Do not keep medications that are outdated or no longer needed. Discard them safely. 
• Do not pour them in wastewater, flush them down the toilet or throw them in the household garbage bin. 
• You should dispose of Lixiana in such a way that prevents animals, children, and others from consuming it.
• For more information on properly disposing of unwanted medications, you can consult your pharmacist, healthcare provider, or local waste disposal company. 

[Note: Discuss with your healthcare professional the proper disposal of unused medicine and any questions you may have regarding its storage.]

What Medications Interact with Lixiana?

Certain medications may interact with Lixiana and interfere with how it may work. Before taking Lixiana, tell your doctor or healthcare provider about all the medications you are taking or plan to take, including all prescription, non-prescription, over-the-counter, and herbal or vitamin supplements. This list is not complete, and there may be other drugs that interact with Lixiana. 

• Warfarin 
• Enoxaparin 
• Fluconazole 
• Erythromycin 
• Clarithromycin 
• Rifampicin 
• Dronedarone 
• Quinidine 
• Verapamil 
• Ciclosporin
• Carbamazepine 
• Phenytoin
• Phenobarbital
• Ibuprofen 
• Aspirin

What Are the Other Lixiana Interactions?

Other than medications, certain herbs, food items, beverages, and supplements may interact with Lixiana and affect its effectiveness. If you are concerned about potential interactions with Lixiana, consult a licensed healthcare provider. They will help you learn how to prevent and manage the symptoms. 

• St John’s wort
• Grapefruit 
• Alcohol
• Coenzyme Q10

[Note: This isn’t a complete list, and there could be other drugs that interact with Lixiana. Tell your doctor about any prescription, over-the-counter medicines, and herbal products.]

What Are the Lixiana Alternatives?

People look for alternative medicines to Lixiana when they do not suit them or do not get the desired results. There are many effective alternative medicines to Lixiana present in the market. However, you should not use any substitute medicines without consulting your healthcare provider. Let your doctor know if you plan to change or start a new medication. They will help you determine the medication that works best for you. Some alternatives for Lixiana are as follows:

• Xarelto (rivaroxaban)
• Pradaxa (dabigatran)
• Eliquis (apixaban)
• Carvedilol (carvedilol)
• Digoxin (digoxin)

[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.]

Lixiana Cost & Coupons

The cost of Lixiana and options for obtaining it at a lower price are influenced by various factors, including health insurance coverage. Many Americans find their health insurance does not cover medications like Lixiana for weight loss, leading to high out-of-pocket expenses- often more than $1000 per month. To manage these costs, some Americans turn to services like Polar Bear Meds, where they can buy Lixiana from Canada in the USA at a reduced price. Additionally, customers can use the Lixiana coupon code WELCOMEPB10 to receive a 10% discount on their first order.

Frequently Asked Questions

How does Lixiana interact with other medications?

Lixiana may interact with certain medications, including other anticoagulants, antiplatelet drugs, and some antifungals. These interactions can affect its efficacy and increase the risk of bleeding. It’s crucial to tell your healthcare provider of all medications you are currently taking or plan to take to manage potential interactions effectively.

Can Lixiana be used in patients with renal impairment?

Lixiana dosage may need adjustment in patients with renal impairment. The medicine is primarily eliminated by the kidneys, so impaired kidney function can affect its clearance. Patients with significant renal issues should consult their healthcare provider for appropriate dosing and monitoring.

How should Lixiana be discontinued?

Lixiana should not be stopped abruptly without medical guidance. If discontinuation is necessary, your healthcare provider will provide a tapering plan or alternative management to minimize the risk of thrombotic events. Always follow professional advice to ensure safety.

What is the impact of liver disease on Lixiana use?

Patients with severe liver disease should avoid using Lixiana due to the risk of increased bleeding and impaired drug metabolism. Moderate liver impairment requires careful monitoring and potential dose adjustments. Ask your healthcare provider for personalized guidance if you have liver conditions.

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