Osphena

Buy Osphena Online from Licensed Canadian Pharmacies

Osphena (generic name, ospemifene) is an effective medicine used after menopause for the treatment of moderate to severe pain during sex (dyspareunia) and vaginal dryness. These symptoms are caused by vulvar and vaginal atrophy, where low estrogen leads to thinning and drying of the vaginal tissues.

If you are diagnosed with either of these conditions mentioned above, your doctor will provide you with a prescription to order Osphena from Canada. It is not a controlled medication and is available in 60 mg tablets.

Osphena is a SERM (selective estrogen receptor modulator). That means it “acts like” estrogen in some parts of the body and differently in others. In the vaginal lining, it helps make tissues thicker, more elastic, and better lubricated, which can ease painful intercourse and dryness over time.

Drug Summary

Osphena is used to treat:

• Dyspareunia (Painful Intercourse)
• Vaginal dryness (due to menopause-related vulvar and vaginal atrophy)

What Are the Benefits of Osphena?

• Patients using this medicine experience improved vaginal dryness and less pain during sex with one once-daily oral tablet.
• Osphena helps thicken and restore the vaginal lining, which becomes thin and fragile after menopause.
• This medicine improves overall vaginal comfort in daily life, not just during sexual activity.

Osphena Dosage for Moderate to Severe Dyspareunia (Painful Intercourse)

• Typical dose: Take a 60 mg tablet by mouth, once a day with food.
• Duration:
• This medicine is used for the shortest duration until your treatment goals are met.
• The need for treatment is usually re-evaluated periodically during follow-up visits.

Osphena Dosage for Moderate to Severe Vaginal Dryness

• Typical dose: One Osphena 60 mg tablet by mouth. Take it once per day with food.
• Duration: It is used until the treatment goals are met with regular assessments.

Dose adjustments:

• No dose adjustment is generally needed for mild to moderate kidney or liver disease.
• Osphena should not be used in women with severe hepatic (liver) disease.

Read the patient leaflet properly after you buy Osphena online from Canada to use it correctly.

• Take your dose, ideally at the same time every day.
• You can take it with food, which helps this medicine to be absorbed better.
• Swallow the tablet whole with water. There’s no need to crush, chew, or break it unless your health care provider approves of any other method.

How Osphena Works

Osphena belongs to a group of medicines called selective estrogen receptor modulators (SERMs). These medicines interact with estrogen receptors, proteins in cells that respond to estrogen.

In the vaginal lining and surrounding tissues, Osphena acts in an estrogen-like way. It helps make the tissue thicker, more flexible, and more moist. This can lessen friction and micro tears that cause pain during sex and can reduce dryness and irritation.

Side Effects of Osphena

Common Osphena side effects may include:

• Hot flushes or hot flashes
• Vaginal discharge
• Muscle spasms or leg cramps
• Headache
• Increased sweating (hyperhidrosis) or night sweats
• Vaginal bleeding or spotting (vaginal hemorrhage)

Serious side effects (rare): Call 911 or go to the nearest hospital right away if any of these side effects occur:

• Allergic reactions
• Endometrial problems
• Blood clot (pulmonary embolism or deep vein thrombosis)
• Stroke or heart attack

Boxed Warning: Risk of Endometrial Cancer

Osphena acts like estrogen in the uterus (the womb), and can affect blood clotting. This increases the risk of endometrial cancer (cancer of the lining of the uterus). Any vaginal bleeding after menopause must be checked immediately.

Below are warnings that you should consider before you start your treatment with this medicine:

• Osphena may raise the risk of deep vein thrombosis (DVT), stroke, and pulmonary embolism (PE). Do not use it if you have a history of:
• Blood clots
• Stroke
• Heart attack
• Women with high blood pressure, high cholesterol, diabetes, obesity, or who smoke may need closer monitoring.
• Do not use this medicine if you have:
• Unexplained vaginal bleeding
• Estrogen-dependent cancers (for example, some uterine cancers)
• Known or suspected pregnancy
• Severe liver disease, because the medicine is processed through the liver
• It is not recommended for women with current or past breast cancer, because safety has not been clearly established.
• If you will undergo major surgery or expect long periods without movement, your health care provider may advise you to stop taking Osphena 60 mg tablets in advance so that the risk of blood clots can be reduced.

Osphena can be helpful for postmenopausal vaginal symptoms, but it must be used under careful medical supervision. Take these precautions while using this medicine:

• It should not be used during pregnancy or while trying to become pregnant.
• Regular pelvic exams, breast exams, and mammograms are recommended.
• Report any unexpected bleeding, spotting, or discharge right away.
• Never share your Osphena tablets to someone else.

If you forget to take a dose of Osphena 60 mg tablets, take it when you remember the same day. If the time is close to your next routine dose, then skip the one you missed and resume your regular dosing schedule.

Do not take extra tablets to cover up for the missed or forgotten dose. When in doubt, speak with your doctor or pharmacist for advice.

If you take more Osphena tablets than prescribed, it may raise the risk of serious side effects, including:

• Abnormal uterine bleeding
• Severe hot flashes
• Symptoms of blood clots or stroke (like chest pain, shortness of breath, leg swelling, or neurologic changes)

But if you suspect an overdose, contact your local emergency services or call Poison Control Center at their toll-free number 1-800-222-1222

How to Store Osphena?

You should store your Osphena tablets carefully, it’s to maintain their effectiveness. Here’s how you can do this:

• Keep it in its original container, tightly closed. It is to protect from moisture.
• Store Osphena at room temperature, 68°F to 77°F (20°C to 25°C).
• Do not use tablets past the expiration date printed on the bottle or pack.
• Dispose of any expired or unused medicine carefully through a medicine take-back program (if available).
• Don’t flush the tablets down the toilet.
• Store this medicine away from children and pets to prevent any accidental ingestion.

Many medicines can affect how Osphena works or be affected by it, especially those processed by the liver enzymes. They include CYP3A4, CYP2C9, and CYP2C19, as well as those that act like estrogens.

Medications that may interact with Osphena include:

• Diflucan (fluconazole)
• Nizoral (ketoconazole)
• Rifadin (rifampin)
• Rimactane (rifampin)
• Coumadin (warfarin)
• Premarin (conjugated estrogens)
• Jantoven (warfarin)

Alternatives to Osphena are available that you may consider after speaking with your doctor. Below are some:

• Ospemifene (generic version)
• Imvexxy vaginal inserts (estradiol)
• Vagifem vaginal tablets (estradiol)
• Estring vaginal ring (estradiol)
• Premarin Vaginal Cream (conjugated estrogens)
• Estrace tablets (estradiol)
• Yuvafem (estradiol vaginal tablet)
• Intrarosa Vaginal Inserts (prasterone)
• Femring (estradiol acetate vaginal ring)

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Osphena Cost & Coupons

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