


Spiriva is a prescription medicine used to help people with COPD (chronic obstructive pulmonary disease). This includes conditions like emphysema & chronic bronchitis. Spiriva contains the active ingredient tiotropium bromide monohydrate, which relaxes the muscles around your airways in the lungs, making it easier to breathe. Spiriva 18 mcg is supplied as a dry powder in capsules for inhalation once daily using the HandiHaler device. Each capsule requires two inhalations per dose.
| Product Name | Spiriva |
|---|---|
| Active Ingredient | Tiotropium bromide monohydrate |
| Drug Class | Long-acting muscarinic antagonist (LAMA) / Anticholinergic bronchodilator |
| FDA Approval Status | FDA-approved for COPD maintenance therapy |
| Available Forms | Inhalation powder in a capsule |
| Strengths Available | 18 mcg |
| Routes of Administration | Inhalation (via HandiHaler device) |
| Administration Frequency | Once daily (1 capsule, inhaled in two breaths) |
| Spiriva Uses | Maintenance treatment of COPD (chronic bronchitis, emphysema). Also, reduces exacerbations and improves lung function |
| Spiriva Contraindications | Hypersensitivity to tiotropium, ipratropium, atropine derivatives, or milk proteins |
| Spiriva Storage | Store capsules in a blister pack at room temperature |
| Prescription Required | Rx only |
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Spiriva is FDA-approved to:
Follow these Spiriva administration guidelines for COPD maintenance:
Follow this Spiriva dosage guide to effectively treat your condition:
| Category | Details |
|---|---|
| Recommended Adult Dose of Spiriva | 1 capsule once daily |
| Maximum Spiriva Dose | Do not exceed 1 capsule (18 mcg) in 24 hours |
| Onset of Action | Relief begins within 30 minutes. Full benefit within 3-7 days |
| Duration of Effect | Continuous bronchodilation for 24 hours |
| Children | Not approved under 18 years |
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Spiriva functions by relaxing the muscles around the airways in the lungs. It blocks certain receptors called muscarinic receptors that normally cause the airway muscles to tighten. By preventing this tightening, Spiriva keeps the airways open, making breathing easier. The effect lasts for a full day, which is why it is taken only once daily. This long-lasting relaxation helps reduce symptoms like shortness of breath and prevents flare-ups in people with COPD.
If you miss a dose of Spiriva 18 mcg capsule (HandiHaler), take it as soon as you remember. However, if it is close to your next scheduled dose, skip the missed Spiriva dose and continue with your regular schedule. Do not take two doses within 24 hours to make up for a missed dose.
Taking Spiriva for COPD more than once daily can lead to overdose-type side effects. This includes dry mouth, constipation, eye discomfort, stomach pain, blurred vision, dizziness, confusion, and heart rhythm problems. If you suspect a Spiriva overdose, contact the poison control center or your healthcare provider immediately. Do not wait for Spiriva overdose symptoms to appear.
Here are some Spiriva side effects you may experience:
| Common Side Effects of Spiriva Capsules | Irregular heartbeat, palpitations | Rare or Serious Side Effects of Spiriva Capsules |
|---|---|---|
| Dry mouth | Throat irritation | Serious allergic reactions |
| Cough | Hoarseness of voice | Sudden breathing difficulty or bronchospasm |
| Upper respiratory tract infection | Headache | Eye pain, blurred vision, halos (possible glaucoma attack) |
| Runny or stuffy nose | Dizziness | Urinary retention (difficulty or pain while urinating) |
| Sinus infection | Nausea | Irregular heartbeat, palpitations |
| Constipation | Stomach upset | Severe chest pain |
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Follow these Spiriva storage guidelines:
Here are the Spiriva interactions you should know:
Consider the following Spiriva alternatives if this medication doesn’t prove to be effective for your condition:
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The information provided here about Spiriva (tiotropium bromide monohydrate) is for general educational purposes only and is not intended as medical advice. Spiriva is a prescription medication, and its use should be prescribed only by a licensed healthcare professional. Individual dosing, administration, and safety considerations may vary, and not all potential side effects, interactions, or contraindications are listed. Do not start, stop, or change your medication regimen without consulting your doctor or pharmacist. This content does not replace professional medical evaluation and should not be used for self-diagnosis or treatment.

Dr. Jackson Miller is a board-certified medicine physician & hospitalist. He is a healthcare professional with a strong background in patient care. With years of experience and a patient-first approach, he believes the foundation of good health is a patient who feels informed and empowered. He contributes to medical content review, drawing on his background in clinical practice and patient education. He focuses on presenting health information in a clear, accurate, and accessible way to help readers make informed decisions. His work emphasizes clarity, evidence-based guidance, and understandable explanations of medical topics.
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