Fesoterodine
Toviaz
Toviaz is a prescription medication approved by the FDA for managing symptoms of overactive bladder, such as urgency, frequency, and urinary incontinence. It is available as an extended-release tablet in 4 mg and 8 mg strengths. The typical dose is 4 mg once each day, which may be increased to 8 mg based on the patient’s response to treatment and the effectiveness of Toviaz. You can take it with or without food. Your doctor will closely monitor your symptoms while you are using this medication. Potential side effects of Toviaz may include dry mouth, constipation, and dry eyes. You should talk to your doctor if you have any queries or concerns prior to using Toviaz. You can buy Toviaz online from reputable platforms to ensure its authenticity.
Product Overview
Toviaz is an FDA-approved extended-release medication containing fesoterodine as its active ingredient. It is used to treat the symptoms of an overactive bladder, including frequent urination, urgency, and incontinence. It works by reducing involuntary bladder muscle contractions, helping to control the bladder and alleviate symptoms. The prescription extended-release tablets are available in two strengths: 4 mg & 8 mg. The typical starting dose is 4 mg once each day, which can be increased to 8 mg based on individual response.
It should be taken at the same time every day and swallowed whole with or without food. This medication is suitable for adults with overactive bladder but requires special care in patients with renal or liver impairment or those who are elderly. Regular monitoring is recommended. Common side effects of Toviaz include dry mouth, constipation & dry eye. Rarely, in some cases, it can also cause severe side effects, including urinary retention or allergic reactions. You should report such symptoms to your doctor immediately.
Toviaz should not be used by patients with urinary or gastric retention, narrow-angle glaucoma, or those allergic to fesoterodine. Always discuss with your healthcare provider before starting or adjusting any medication, especially if taking other drugs that may interact with Toviaz. If you have missed a dose, you should take it as soon as remembered, unless the time to take the next dose is almost here. In case of an overdose, you should seek immediate medical assistance. For personalized guidance regarding dosage, storage, and more, get in touch with an expert medical practitioner. If you want to buy Toviaz online, obtain it using your doctor’s prescription.
What Are the Uses of Toviaz?
This medication is used to treat:
- Overactive Bladder
- Bladder Muscle Dysfunction
- Urinary Incontinence
What Are the Forms & Strengths of Toviaz?
Toviaz (fesoterodine fumarate) is available in the following forms and strengths:
Extended-Release Tablets: These are designed to release the medication slowly over time.
- 4 mg tablets
- 8 mg tablets
What Are the Recommended Dosage of Toviaz?
The dosage of Toviaz for overactive bladder treatment is usually based on factors such as the effectiveness of the medication and the tolerance, and the needs of the patient. While the dosage schedule mentioned below is generalized, the usual initial dose is 4 mg once daily. However, if your doctor has prescribed you a different dosage, follow their instructions and do not make any changes to your medication dosage or duration without consulting your doctor first, as it can cause harm. Additionally, avoid using it in large doses, more or less than prescribed, or more frequently.
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- Starting Dosage: The usual starting dose is 4 mg once daily.
- Maintenance Dosage: Depending on your response to the medication and tolerance, your doctor may increase the dose to 8 mg once daily if the lower dose is not sufficiently effective.
- Adjustments for Special Populations:
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- Elderly Patients: Older adults may start with the lower dose to assess how well they tolerate the medication.
- Patients with Renal or Liver Impairment: The dose should not exceed 4 mg once daily for patients with moderate to severe renal or moderate hepatic impairment.
[Note: Remember, these recommendations will differ from person to person. We suggest discussing it with your medical expert, and they’ll customize your Toviaz dosage accordingly.]
How to Use Toviaz?
Before using Toviaz for urinary frequency control, you should carefully read and follow the directions for use given on the prescription label or if your pharmacist or healthcare provider has given you a patient information leaflet (PIL) and medication guide. If you have any queries regarding Toviaz’s use or if you have difficulty understanding any parts of the leaflet, ask your doctor or pharmacist.
- Take Toviaz precisely as prescribed by your doctor, typically once daily. It’s important to take it simultaneously each day to maintain consistent medication levels.
- Do not crush, chew, or break the tablet. Swallow it whole with a glass of water.
- Toviaz can be taken with or without food, depending on your preference or as advised by your healthcare provider.
- If you miss a dose of Toviaz, take it as soon as you remember. However, if it’s nearly time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for the missed one.
- Regular check-ups with your healthcare provider are necessary to monitor your medication response and make any necessary adjustments to your treatment.
[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They’ll tailor it as needed over time.]
How Does Toviaz Work?
Toviaz (fesoterodine) functions as an antimuscarinic medication that targets specific receptors in the bladder known as muscarinic receptors. By binding to these receptors, Toviaz effectively blocks the action of acetylcholine, a neurotransmitter involved in the involuntary contraction of the bladder muscle. This action helps to relax the bladder, reducing the urgent and frequent need to urinate and the incidence of involuntary urine leakage, which are common symptoms associated with overactive bladder syndrome. This mechanism helps improve urinary control and extends the bladder’s capacity, thereby increasing comfort and quality of life for individuals with urinary incontinence and overactivity.
Important Safety Information for Using Toviaz
What Are the Side Effects of Toviaz?
Common Side Effects of Toviaz: Toviaz can cause certain temporary side effects for some people who use it. These side effects subside without any medical intervention in a couple of days or weeks. However, if they persist or become worrisome, it is essential to let your doctor or healthcare provider know. This list does not include all possible side effects of Toviaz, and there may be others as well. Talk to your doctor if you have any concerns regarding Toviaz use beforehand. Common side effects of this medication include:
- Dry mouth: This is one of the most commonly occurring side effects of Toviaz, primarily caused by its anticholinergic properties. It can also reduce the normal saliva production which leads to a feeling of dryness in the mouth, which can cause discomfort and difficulty swallowing or speaking. To manage symptoms of a dry mouth, you should stay adequately hydrated, chew sugar-free gum, and use saliva substitutes if you have severe dry mouth. Avoiding tobacco and alcohol is also helpful.
- Constipation: The anticholinergic action slows down the digestive system, reducing bowel motility. To prevent or manage constipation, you should increase fiber intake, drink plenty of water & engage in regular physical activity. After consulting with your doctor, you can use oral laxatives occasionally to avoid dependency. If constipation becomes severe or persistent, you should consult a doctor who may recommend adjusting the dose or exploring alternative treatment options.
- Headache: This is a frequently reported side effect associated with the use of Toviaz, which could be due to the drug’s effects on neurotransmitters in the brain. Headaches can also be caused by dehydration. To manage this side effect, you should stay hydrated, rest in a quiet and dark environment & use over-the-counter pain relievers, including acetaminophen or ibuprofen, after talking to your doctor. If headaches become frequent or severe, it’s important to contact a doctor to rule out other underlying causes or consider switching to a different medication.
- Dizziness: This can happen due to the medication’s effects on the central nervous system which can a drop in blood pressure or affect balance, especially when standing up quickly. To prevent dizziness, you should rise slowly from sitting or lying down after extended periods to avoid sudden movements. You can also try to stay hydrated to prevent dizziness. If dizziness is frequent or leads to fainting, it is important to consult a healthcare provider.
- Nausea: This is caused by the gastrointestinal effects of Toviaz, which may include slowed gastric emptying. This can cause discomfort in the stomach. To manage or prevent symptoms of nausea, you should take the medication with food or a milky drink and eat smaller, more frequent meals. Avoiding heavy or greasy foods can also help prevent the side effect. If nausea becomes severe or persistent, you may require a dosage adjustment.
- Blurred vision: Due to the anticholinergic activity of Toviaz, it can affect the eye’s ability to focus properly. This can cause temporary blindness or short-sightedness. You should ensure that the lighting is adequate when reading or doing tasks that require clear vision. If blurred vision persists or becomes bothersome, it is important to discuss the issue with a healthcare provider, as it could indicate the need to adjust the medication or dosage.
- Urinary tract infection: Toviaz works by relaxing the bladder muscles, which can lead to incomplete emptying of the bladder. When urine stays in the bladder for long time, it can create an environment that promotes bacterial growth, leading to infections. Preventing UTIs involves ensuring that the bladder is fully emptied during urination, drinking plenty of water to flush out bacteria, and practicing good hygiene. If symptoms of a UTI develop, you should consult a healthcare professional.
- Dry eyes: This is another side effect of Toviaz which can occur due to the medication’s anticholinergic action. like dry mouth, which is caused by the drug inhibiting the body’s normal secretions. To manage symptoms of dry eyes, you should use lubricating eye drops or artificial tears. It is also helpful to avoid environments that may exacerbate dryness, such as windy or air-conditioned spaces. Wearing sunglasses when under the sun can also protect the eyes from further irritation.
Serious Side Effects of Toviaz
Toviaz, like all medications, can cause serious side effects, although they are relatively rare. Patients should be aware of these potential risks and seek immediate medical attention if they experience any of the following serious side effects:
- Angioedema: Swelling of the face, lips, tongue, or throat, which can cause difficulty breathing and swallowing. This requires urgent medical intervention.
- Severe Allergic Reactions: Symptoms may include hives, rash, itching, chest tightness, or severe dizziness.
- Urinary Retention: Inability to urinate or severe difficulty urinating, which might require medical attention to avoid further complications.
- Central Nervous System Effects: Severe dizziness, confusion, hallucinations, or memory problems can occur, particularly in elderly patients or those with existing CNS disorders.
- QT Prolongation and Heart Rhythm Changes: Unusually fast or irregular heartbeat, palpitations, or severe dizziness, which could indicate a potentially life-threatening heart rhythm disorder.
- Aggravation of Symptoms of Dementia: In older adults, particularly those with conditions like Alzheimer’s disease, Toviaz can cause confusion, agitation, and worsening of dementia symptoms.
- Vision Changes: Including blurred vision and difficulty focusing may signal severe eye problems, especially in those with controlled narrow-angle glaucoma.
[Note: Remember, this list may not cover all possible side effects. Always consult with your healthcare giver for medical advice about side effects.]
Are There Any Warnings for Toviaz?
While using toviaz for bladder health, you should be aware that it can cause serious health issues, particularly for specific groups. If you have concerns, discussing alternative treatments with your doctor or pharmacist is crucial.
- Angioedema: Toviaz may cause swelling of the face, lips, tongue, or throat, a serious allergic reaction that can obstruct breathing. This reaction can occur with the first dose or after multiple doses. If you experience these symptoms, immediately stop taking the medication and seek emergency medical assistance.
- Urinary and Gastrointestinal Blockages: Toviaz should not be used by individuals with bladder blockages, as it can impair your ability to completely empty your bladder, potentially leading to kidney damage and other complications. Additionally, avoid fesoterodine if you have blockages in your stomach or intestines, as it can slow digestion and exacerbate gastrointestinal symptoms.
- Vision Changes: Toviaz can affect vision, particularly in those with glaucoma. It is not recommended for those with uncontrolled narrow-angle glaucoma. Consult your healthcare provider to determine your specific type of glaucoma before taking this medication.
- Dizziness and Drowsiness: Toviaz can cause dizziness and drowsiness, impacting your alertness. Avoid driving or engaging in activities requiring sharp focus until you understand how the medication affects you.
- Myasthenia Gravis: If you suffer from myasthenia gravis, a condition that weakens muscles, consult your healthcare provider before using Toviaz as it may worsen symptoms.
What Are the Toviaz Precautions?
- Allergic Reactions: Avoid Toviaz if you have any known allergy to fesoterodine or its components, which can cause symptoms like hives, swelling, and difficulty breathing.
- Bladder Blockage: If you have a history of urinary or gastric retention or uncontrolled narrow-angle glaucoma, use Toviaz with caution. It can aggravate these conditions.
- Kidney or Liver Impairment: Patients with moderate to severe kidney or liver impairment may require dosage adjustments or close monitoring due to the increased risk of side effects.
- Central Nervous System Effects: Toviaz may cause dizziness and sleepiness; avoid driving or operating heavy machinery until you know how Toviaz affects you.
- Anticholinergic Burden: Since Toviaz has anticholinergic properties, using it with other medications with similar effects can increase the risk of anticholinergic side effects like dry mouth, constipation, and confusion, especially in elderly patients.
- Heart Rhythm Changes: Toviaz can potentially cause QT prolongation, a heart rhythm disorder that can be serious. This is more likely in those with existing heart conditions or those taking other medications that affect heart rhythm.
- Heat Prostration: Due to decreased sweating, Toviaz can increase the risk of heat prostration (due to decreased sweating) in hot environments.
- Pregnancy and Breastfeeding: Discuss with your healthcare provider if you are pregnant or plan to become pregnant. The effects of Toviaz during pregnancy are not well-studied. It’s also unknown whether Toviaz passes into breast milk.
What Are the Contraindications of Toviaz?
The contraindications for using Toviaz include:
- Allergy to fesoterodine or any component of the formulation: Patients with a known hypersensitivity to fesoterodine or any of its components should not take Toviaz.
- Urinary retention: Those who have or are at risk of urinary retention should not use Toviaz.
- Uncontrolled narrow-angle glaucoma: Patients with this condition should avoid Toviaz due to the risk of exacerbating their symptoms.
- Gastric retention: Toviaz is contraindicated in patients with gastric retention, as the medication may worsen this condition.
- Severe liver impairment: Due to reduced clearance of the drug, patients with severe liver impairment should not use Toviaz.
What If You Missed a Dose of Toviaz?
To get the most benefit out of Toviaz, you should stay consistent in using your medicine. To help you remember to take it, you can fix a time that is most convenient for you and take it at that same time each day. If you miss a dose of Toviaz, take it as soon as you remember. However, if it’s almost time for your next scheduled dose of this medication, skip the missed dosage and continue with your routine dosing schedule. Do not take two doses simultaneously to make up for the missed dose. It’s important to maintain a regular schedule to ensure the medication’s effectiveness, so try setting reminders or alarms to help you remember your doses.
[Note: If you have missed a dose of your medication and are unsure about when to take the next one, immediately consult your doctor or pharmacist.]
What Happens If You Take Too Much of Toviaz?
Taking too much Toviaz can lead to an overdose, which may result in severe symptoms requiring immediate medical attention. Overdose symptoms could include severe dry mouth, blurred vision, difficulty urinating, constipation, confusion, hallucinations, fast or irregular heartbeat, and possibly seizures. In extreme cases, an overdose may lead to delirium or coma. If you suspect an overdose of Toviaz, seek emergency medical care or call the Poison Help line immediately to manage the situation effectively.
[Note: If you consumed more than the recommended dose, get medical help right away or call the Poison Help line at 1-800-222-1222.]
How to Store a Toviaz?
Storing Toviaz (fesoterodine) properly is important to maintain its effectiveness. Here are the recommended storage guidelines:
- Temperature: Store Toviaz at room temperature, ideally between 20°C to 25°C (68°F to 77°F). Avoid storing the medication in areas where it might be exposed to excessive heat or cold.
- Humidity: Keep Toviaz in a dry place. Avoid locations that are prone to moisture, such as bathrooms or near sinks.
- Original Packaging: Retain Toviaz in its original packaging until ready to use. This helps protect the medication from light and moisture.
- Safety: Ensure that Toviaz is kept out of reach of children and pets to prevent accidental ingestion.
- Disposal: If you need to dispose of expired or unused Toviaz, do not throw it in the trash or flush it down the toilet. Check with your pharmacist or a local waste disposal company about safe disposal methods.
[Note: Discuss with your healthcare professional about the proper disposal of any unused medicine and any questions you may have regarding its storage.]
What Medications Interact with Toviaz?
Toviaz may interact with several medications, which can affect how Toviaz or the other medications work or increase the risk of serious side effects. It’s important to discuss all your current medications with your healthcare provider before starting Toviaz. Here are some common types of medications that can interact with Toviaz:
- Anticholinergics: Concurrent use of other anticholinergic drugs can enhance the effects of Toviaz, potentially leading to increased side effects such as dry mouth, constipation, and urinary retention.
- CYP3A4 Inhibitors: Medications that inhibit the enzyme CYP3A4 can increase the levels of fesoterodine in the blood, enhancing its effects and side effects. Examples include:
- Ketoconazole
- Itraconazole
- Clarithromycin
- Ritonavir
- CYP3A4 Inducers: Drugs that induce CYP3A4 can decrease the blood levels of fesoterodine, potentially reducing its effectiveness. Examples include:
- Rifampin
- Carbamazepine
- Phenobarbital
- Potassium Channel Blockers: These can interact with fesoterodine and exacerbate effects on cardiac function.
- Cholinesterase Inhibitors: Used primarily in Alzheimer’s disease, these drugs can oppose the action of anticholinergics like Toviaz and might exacerbate bladder symptoms.
[Note: This isn’t a complete list, and there could be other drugs that interact with Toviaz. Make sure to tell your doctor about any prescription, over-the-counter medicines, and herbal products you’re taking.]
What Are the Toviaz Alternatives?
While Toviaz is an effective extended-release medicine used to treat symptoms of an overactive bladder, it may not be suitable for everyone due to contraindications or hypersensitivity to any of its ingredients. In such cases, people look for alternatives to Topiaz. While there are many alternatives available on the market, you should not use them without first discussing them with your doctor, as they can cause unfavorable side effects. Some of the alternatives include:
- Ditropan XL (oxybutynin)
- Detrol (tolterodine)
- Enablex (darifenacin)
- Vesicare (solifenacin)
- Sanctura (trospium)
- Myrbetriq (mirabegron)
- Urispas (flavoxate)
[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.]
Toviaz Cost & Coupons
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Frequently Asked Questions
Is it safe to discontinue Toviaz abruptly?
It is advisable to consult your healthcare provider before stopping Toviaz. While this medication helps to relax the bladder muscles and manage symptoms of overactive bladder, it does not cure the condition. Discontinuing the drug without medical guidance might lead to the return of symptoms. However, in the case of a severe allergic reaction, you should immediately stop taking the medication and seek emergency medical assistance.
Can I cut Toviaz tablets in half?
You should not chew, cut, or crush fesoterodine Toviaz tablets. They are designed as extended-release tablets to release the medication gradually over time. Altering the tablet by cutting it could disrupt this mechanism, potentially leading to improper release. Discuss alternative treatments or swallowing the tablets; it’s important to discuss alternative therapies or forms of medication with your healthcare provider.
Does Toviaz lead to constipation?
Constipation is indeed a common side effect associated with Toviaz. To help mitigate this, consider incorporating high-fibre foods into your diet and staying hydrated by drinking ample physical activity. Additionally, you can consult with your healthcare provider about using a fiber supplement. If constipation becomes troublesome, your provider may consider adjusting your dosage or exploring alternative treatment options.
Can Toviaz cause urinary retention?
While uncommon, Toviaz can cause urinary retention, where the bladder retains too much urine. Clinical studies indicate that about 1% of people experience this side effect. It’s important to avoid taking Toviaz if you already have urinary retention or any urinary tract blockage, as this can lead to kidney injury and other complications. Consult your healthcare provider to determine if Toviaz is suitable for you.
How long does it take for Toviaz to start working?
In one study, people taking Toviaz for overactive bladder (OAB) symptoms saw improvement after 1 week of treatment. However, it can take up to 8 weeks or longer to see more noticeable results. It’s important to continue taking Toviaz daily, even if you don’t see immediate results.
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