Insulin Glargine

Toujeo Solostar Prefilled Pens

Toujeo Solostar Pen contains a long-acting insulin used to manage blood sugar levels in people with diabetes. It is FDA approved and is available as a pre-filled pen. It has the active ingredient, Insulin Glargine, which works by continuously releasing insulin into the bloodstream, maintaining steady glucose levels. Dosages vary based on individual needs and type of diabetes, with frequent monitoring recommended to adjust doses. It is suitable for adults with both type 1 and type 2 diabetes, it should not be used for diabetic ketoacidosis or by those with allergies to its components. You can buy Toujeo Solostar 300 units/ml pens online from Canada with a valid prescription that can be received from a primary caregiver.

Product Overview

Toujeo Solostar is a long-acting insulin formulation designed to help manage blood glucose levels in individuals with type 1 and type 2 diabetes. This medication, containing the active ingredient Insulin Glargine, is administered through a pre-filled disposable pen. It mimics natural insulin by forming micro precipitates under the skin that slowly release insulin, providing up to 24 hours of basal insulin coverage. 

Toujeo Solostar is typically prescribed in specific dosages based on the patient’s body weight and previous insulin use, with adjustments made according to blood sugar monitoring results.

For new patients, the starting dose can range from 0.2 units/kg to half of the estimated total daily insulin dose, complemented by mealtime insulin for type 1 diabetes. 

Regular glucose monitoring is crucial to optimize the dosage and minimize risks such as hypoglycemia. Toujeo Solostar is not suitable for treating diabetic ketoacidosis or for patients with known hypersensitivity to its ingredients. Its efficacy and safety profile make it a valuable option for long-term diabetes management, but it requires careful dosage management and regular medical consultation.

What Are the Uses of Toujeo SoloStar Pens?

Toujeo Solostar 300 units/ml is used to treat:

• Diabetes mellitus

[Important warning: It is not recommended for the treatment of diabetic ketoacidosis.]

How Many Units Are in a Toujeo Solostar Pen?

• Toujeo Solostar comes in the form of Pre-filled disposable pen.
• This pen contains 450 units of insulin glargine in 1.5 milliliters (mL) of solution. It can give up to 80 units of insulin glargine in a single injection.

What Are Typical Dosage of Toujeo Solostar Prefilled Pens?

Your doctor will usually begin with a low dose and adjust it gradually to find the right dosage for you. Below is information on dosages that are commonly recommended, but it’s important to follow the specific dosage your doctor prescribes. Your doctor will determine the best dosage based on your individual needs to ensure safe and effective treatment.

For Insulin-Naive Patients with Type 1 Diabetes

• A starting dose of 1/3 to 1/2 of the daily insulin dose is recommended. Short-acting insulin should be given during each meal to complete the daily insulin dose, which should be 0.2 to 0.4 units per kilogram of body weight.
• The maximum glucose-lowering effect may take five days to manifest, and the first dose may not be adequate to cover metabolic needs within 24 hours. 

For Insulin-Naive Patients with Type 2 Diabetes

• In the beginning, 0.2 units per kilogram of body weight should be taken once a day.

For Patients with Either Type 1 or Type 2 Diabetes Already on Insulin Therapy

• Start Toujeo at the same dose as your long-acting insulin once daily if you are currently on it. To maintain the same level of glycemic control as patients taking Lantus (insulin glargine, 100 units/ml), Toujeo will require a higher daily dose.
• Start Toujeo at 80% of the total daily dosage of NPH or insulin detemir for patients on twice-daily long-acting or intermediate-acting insulin.
• During the first few weeks of Toujeo treatment, monitor glucose frequently.

[Note: These Toujeo Solostar dosage recommendations may differ from individual to individual. Discuss it with your healthcare professional, and they’ll decide your dosage accordingly.]

How to Use Toujeo Solostar Pens?

Here’s a step-by-step guide on how to administer Toujeo Solostar:

• Step 1. Make sure you have the correct medication and that it has not expired.
• Step 2. Wash your hands thoroughly with soap and water. If necessary, clean the injection site with an alcohol swab and let it dry.
• Step 3. Check the Toujeo Solostar pen for any damage or leaks. If you notice anything unusual, do not use it.
• Step 4. If this is your first time using the pen or if you haven’t used it in a while, you may need to prime it. This involves dialing a dose and pressing the injection button to release a drop of insulin. Follow the instructions provided with your pen.
• Step 5. Dial the dose of insulin prescribed by your healthcare provider and ensure the dose is set correctly.
• Step 6. Insert the needle into the injection site at a 90-degree angle (perpendicular to the skin). Press the injection button fully to deliver the dose of insulin.
• Step 7. After injecting the insulin, keep the needle in place for a few seconds to ensure the entire dose has been delivered.
• Step 8. Carefully remove the needle from your skin. Properly dispose of it in a sharps container.
• Step 9. Store the Toujeo Solostar pen according to the manufacturer’s instructions, typically at room temperature (between 59°F and 86°F. Do not freeze it or expose it to high temperatures.
• Step 10. Regularly monitor your blood sugar levels as recommended by your healthcare provider to ensure that your diabetes is being adequately managed.

[Note: Your doctor will decide the right amount of Toujeo Solostar for you based on your condition, following guidelines and studies on the drug. They’ll adjust your Pregnyl dosage as needed over time.]

How Does Toujeo Work in the Body?

Toujeo Solostar contains Insulin Glargine, a long-acting insulin analogue. It works by imitating the natural insulin produced by the body. After injection, insulin glargine forms micro precipitates in the fatty tissue under the skin, from which small amounts of insulin are continuously released into the bloodstream over an extended period (up to 24 hours). This steady release helps to regulate blood sugar levels between meals and overnight, providing consistent basal insulin coverage. Toujeo Solostar treats diabetes by controlling high blood sugar levels over time.

What Are the Safety Guidelines for Using Toujeo Insulin?

What Are the Side Effects of Toujeo Solostar Insulin?

Common Toujeo SoloStar Side Effects: Toujeo SoloStar, used to manage blood sugar in people with diabetes, may cause some common and usually temporary side effects. These side effects typically last a few days to a couple of weeks. If they continue for a longer period, become uncomfortable, or worsen, it’s important to reach out to your doctor or pharmacist for advice. Here are some of the common side effects of Toujeo SoloStar:

• Low blood sugar levels: You may experience dizziness, sweating, shakiness, or confusion when your blood sugar drops too low.
• Injection site reactions: After using Toujeo, you might notice redness, itching, or swelling where you injected the medication. These reactions usually go away on their own.
• Weight gain: Some people may gain weight while using Toujeo SoloStar, which is a common side effect of insulin therapy.

Mild Toujeo SoloStar Side Effects: In addition to the common side effects, Toujeo SoloStar can cause mild side effects that are usually temporary and may improve as your body gets used to the medication. If these mild side effects don’t go away or start to bother you, it’s a good idea to speak with your healthcare provider. Here are some mild side effects you might experience:

• Headache: You may feel mild discomfort or pain in your head, which can be a temporary reaction to the medication.
• Nasopharyngitis: This is the inflammation of the nose and throat, often causing a stuffy or runny nose and mild throat discomfort.
• Upper respiratory tract infection: You might notice cold-like symptoms, such as a cough or sore throat.
• Nausea: Some people may feel slightly sick to their stomach after starting Toujeo.

Serious Toujeo SoloStar Side Effects: While Toujeo SoloStar is a helpful medication for managing diabetes, it can sometimes cause serious side effects that need urgent medical attention. If you experience any of the following side effects while using Toujeo SoloStar, contact your doctor immediately. If the side effects appear life-threatening or you think you are having a medical emergency, call your local emergency number or 911 right away. Serious side effects of Toujeo SoloStar include:

• Severe hypoglycemia: This is dangerously low blood sugar that requires help from others to treat.
• Hypokalemia: Low potassium levels in your blood can cause muscle weakness, cramps, or an irregular heartbeat.
• Allergic reactions: Watch for signs like rash, itching, swelling, or difficulty breathing.
• Injection site lipodystrophy: This involves changes in the fat tissue at the injection site, causing lumps or indentations.
• Fluid retention or edema: Swelling caused by fluid buildup, often noticeable in the legs or ankles.

[Note: This list may not cover all possible side effects of Toujeo Solostar. Always consult with your healthcare giver for medical advice about side effects.]

Who Should Not Take Toujeo?

Before starting Toujeo, it’s important to consult with your doctor. Certain people should avoid using Toujeo, including those with a known allergy to insulin glargine or any other ingredient in the medication. Always speak with your healthcare provider to determine if Toujeo is safe and appropriate for you:

• Hypoglycemia Risk: Toujeo Solostar can cause hypoglycemia (low blood sugar), especially if the dose is too high, if meals are skipped, or if strenuous exercise is not compensated with additional food intake. Severe hypoglycemia can lead to unconsciousness, seizures, or even death. Patients should be educated on recognizing and managing hypoglycemia.
• Adjustment of Dosage: Your dosage may need to be adjusted when initiating or discontinuing concomitant medications, changing meal patterns, during intercurrent illnesses, or changes in physical activity. Close monitoring of blood glucose levels is essential in such situations.
• Hypersensitivity Reactions: Toujeo Solostar has been associated with hypersensitivity reactions, including anaphylaxis, angioedema, and generalized skin reactions. If signs of hypersensitivity reactions occur, discontinue Toujeo Solostar and initiate appropriate treatment promptly.
• Injection Site Reactions: Insulin therapy may cause injection site reactions such as pain, erythema, pruritus, rash, swelling, or bruising. Rotate injection sites within the same region to reduce the risk of lipodystrophy.
• Hypokalemia Risk: Insulin therapy can lead to hypokalemia (low potassium levels) due to the redistribution of potassium from the extracellular space to the intracellular space. Monitor potassium levels and adjust treatment as necessary.
• Fluid Retention and Heart Failure: Excessive insulin dosing can cause fluid retention and exacerbate heart failure. Patients with heart failure or renal impairment may be more susceptible to these effects. Use caution and monitor for signs and symptoms of fluid retention.
• Hypoglycemia in Elderly Patients: Older people are at increased risk of hypoglycemia due to reduced renal function, altered drug clearance, and increased sensitivity to insulin. Adjust dosage cautiously in elderly patients and monitor closely for hypoglycemia.
• Driving and Operating Machinery: Hypoglycemia can impair concentration and reaction time, affecting the ability to drive or operate machinery. Patients should be advised to take precautions to avoid hypoglycemia while performing activities that require mental alertness.
• Renal or Hepatic Impairment: Insulin requirements may be altered in patients with renal or hepatic impairment. Monitor blood glucose levels closely and adjust insulin dosage as needed.

What Precautions Should Be Taken When Giving Insulin Glargine?

Before starting treatment with Toujeo Solostar (insulin glargine) (1.5 ML/pen) 300 units/ml, it’s essential to discuss your health history with your doctor. Insulin Glargine may not be suitable if you have certain medical conditions or factors that could affect its safety or effectiveness. Some key considerations include:

• Toujeo Solostar can lower your blood sugar levels, so be vigilant for signs of low blood sugar (hypoglycemia).
• If you have kidney or liver problems, discuss them with your doctor. You may need particular adjustments to your Toujeo Solostar dosage.
• Watch out for signs of allergic reactions, like rash or swelling. Let your doctor know if you experience any.
• Change where you inject Toujeo Solostar to prevent skin reactions or changes in fat under your skin.
• If you’re pregnant or breastfeeding, talk to your doctor before using Toujeo Solostar. Your insulin needs may change during this time.
• Toujeo Solostar’s safety and effectiveness in children need to be established. If your child needs it, consult your doctor.
• You may be more sensitive to Toujeo Solostar’s effects if you’re older. Your doctor may need to adjust your dosage and monitor you closely.
• Toujeo Solostar could lower your potassium levels, especially if you have kidney problems or take certain medications. Your doctor will monitor this.
• If you change your exercise or diet habits, let your doctor know. You may need adjustments to your Toujeo Solostar dosage.
• Low blood sugar can affect your ability to drive safely. If you feel hypoglycemic, avoid driving until your blood sugar stabilizes.

Are There Any Contraindications for Toujeo Solostar Insulin?

Toujeo Solostar insulin should not be used by the people mentioned below:

• Do not use Toujeo if you are experiencing an episode of hypoglycemia.
• Toujeo is not suitable for treating diabetic ketoacidosis. 
• Avoid Toujeo if you are allergic to insulin.
• Toujeo is not approved for use in children younger than six years old.

What Happens If You Miss a Dose of Long-Acting Insulin?

Here are some guidelines that you can follow when you miss a dose of Toujeo Solostar (insulin Glargine):

• If you remember shortly after you missed the dose and there’s still a significant amount of time before your next scheduled dose, go ahead and take it.
• If it’s almost time for your next scheduled dose, ignore the missed one and take your next dose at the regular time. 
• Do not double the dose to make up for the missed one.

[Note: If you have missed a Toujeo Solostar dose and are still determining when to take the next one, immediately consult your doctor or pharmacist.]

What Happens If You Take Too Much Toujeo?

An overdose of Toujeo Solostar can lead to severe hypoglycemia, causing symptoms like shakiness, confusion, and, in extreme cases, loss of consciousness or death.

[Note: If you administered more than the recommended dose of Toujeo Solostar, get medical help immediately or call the Poison Help line at 1-800-222-1222.]

What Temperature Should Toujeo Insulin Be Stored At?

Here are some interactions you may follow to store your Toujeo Solostar prefilled pens properly:

• Toujeo Solostar should be stored in the refrigerator between 36°F and 46°F. Do not freeze it. If it is accidentally frozen, discard it.
• An unopened Toujeo Solostar pen can be kept at room temperature for up to 28 days. Avoid exposure to excessive heat or direct sunlight.
• Keep Toujeo Solostar pens away from direct light in the refrigerator and at room temperature.
• If a Toujeo Solostar pen has not been opened, keep it in the refrigerator until the expiration date is printed on the label. Once opened, it can be stored at room temperature for up to 28 days.
• Store Toujeo Solostar pens out of the reach of children and pets.

[Note: Discuss the proper storage and disposal of Toujeo Solostar with your healthcare professional.]

What Medications Interact with Toujeo (Insulin Glargine)?

Drug interactions can affect how your medications work or could increase the risk of serious side effects. This information does not cover all possible interactions. It’s important not to start, stop, or change the dosage of any medicines without your doctor’s permission. Here are some drugs that may interact with Toujeo Solostar:

• Amlodipine, Carvedilol, Metoprolol: These can lower blood pressure, which may make you more prone to low blood sugar (hypoglycemia).
• Aspirin, Atorvastatin, Rosuvastatin, Simvastatin: These can affect how your body handles insulin, potentially causing blood sugar fluctuations.
• Furosemide, Hydrochlorothiazide: Diuretics can affect potassium levels, increasing the risk of low potassium (hypokalemia) while using insulin.
• Gabapentin, Tramadol: These may mask the symptoms of low blood sugar, making it harder to recognize hypoglycemia.
• Glimepiride, Januvia, Jardiance, Metformin: These are also diabetes medications and can increase the risk of low blood sugar when taken with insulin.
• Humalog, NovoLog, Ozempic, Trulicity, Victoza: These are other insulin or diabetes treatments. Using them with Toujeo may require careful monitoring to avoid low blood sugar.
• Levothyroxine: Thyroid medications can affect your insulin needs, so adjustments might be needed.
• Omeprazole, Pantoprazole: These acid reducers may impact how insulin is absorbed.
• Vitamin B12, Vitamin D3: While not directly dangerous, these vitamins can alter how your body manages nutrients and energy, affecting overall health when combined with insulin.

[Note: This is not a complete list; there could be other drugs that interact with Toujeo Solostar. Tell your doctor about prescription, over-the-counter medicines, and herbal products.]

What Is an Alternative to Insulin Glargine Solostar?

Toujeo Solostar is a long-acting insulin that helps manage blood sugar for people with Type 1 or Type 2 diabetes. However, if you’re facing issues like Toujeo Solostar price, side effects, or allergic reactions, there are alternative options available. Here they are:

• Basaglar (insulin glargine)
• Lantus (insulin glargine)
• Semglee (insulin glargine)
• Levemir (insulin detemir)
• Tresiba (insulin degludec)
• Zepbound (tirzepatide)
• Glumetza (metformin)
• Rezvoglar (insulin glargine)
• Toujeo Max SoloStar (insulin glargine)
• Toujeo (insulin glargine)
• Lantus SoloStar (insulin glargine)

[Note: Your doctor will choose the best Toujeo Solostar alternative. Only use these alternative medications after consulting your healthcare provider. Taking them by yourself may cause serious side effects.] 

Toujeo Solostar Coupons & Cost

Toujeo Solostar, a long-acting insulin for diabetes management, can be prohibitively expensive in Americans, with prices often making it difficult for patients to afford without insurance. Buy Toujeo Solostar online from Canada through Polar Bear Meds to significantly lower your healthcare costs. We offer Toujeo Solostar at a much-reduced price compared to U.S. pharmacies. Use the exclusive Toujeo Solostar coupon code “WELCOMEPB10” to receive an extra 10% off your first purchase. Additionally, joining our referral program can help you save even more, potentially up to $200 on future orders. Polar Bear Meds ensures that essential diabetes medications are accessible and affordable for U.S. residents.

Frequently Asked Questions

How long does it take for Toujeo to take effect?

Toujeo SoloStar is a long-acting insulin that works several hours after injection and works evenly for 24 hours. It typically takes about 6 hours to begin its effects after injection, and its impact may last more than 36 hours. Remember to consult your healthcare provider for personalized guidance on using Toujeo. 

How long does Toujeo SoloStar last after opening?

An opened Toujeo SoloStar pen can be stored at room temperature below 86°F (30°C) and should be used within 56 days. Remember not to store the pen with the needle attached, and always dispose of needles properly in a puncture-proof container.

How long can Toujeo (insulin glargine) be used after the expiration date?

Do not use your pen after the expiration date. If your Toujeo SoloStar has expired, it’s essential to dispose of it properly and obtain a new one. Using expired insulin can affect its effectiveness and may not provide the desired blood sugar control. Always follow your healthcare provider’s instructions regarding insulin usage and storage.

Can Toujeo be given twice a day?

Even though Toujeo SoloStar is usually given once a day, some people may experience better blood sugar control if the dose is split and given twice daily (every 12 hours). Toujeo is particularly beneficial for those who suffer from hypoglycemia in the morning or persistent hyperglycemia at dinner. However, following your healthcare provider’s guidance regarding insulin usage and dosing is essential.

How long does it take for Toujeo to lower blood sugar?

Toujeo works gradually to lower your blood sugar, but it can take up to 5 days for the full effect to be noticed. Because of this, any adjustments to your dosage should be made cautiously and only every 3 to 4 days. This allows your doctor to monitor how your body is responding to the medication and make the appropriate changes if needed.

Where is the best place to inject Toujeo?

When injecting Toujeo, it’s important to choose the right spot for the best absorption and comfort. You should inject it into areas of soft tissue. The recommended places are the outer thigh, the soft area on the back of your upper arm, or the abdomen—making sure to avoid the 2-inch area around your belly button. Also, avoid injecting too close to the bony area above your knee.

What is the difference between Toujeo SoloStar and Toujeo Max SoloStar?

Toujeo comes in two types of insulin pens: the SoloStar and the Max SoloStar. The Toujeo SoloStar pen is similar to the Lantus pen and delivers a maximum of 80 units of insulin per dose. On the other hand, the Toujeo Max SoloStar pen is designed for larger doses, allowing you to dial up to 160 units of insulin per injection. The Max SoloStar is more convenient for those who need higher doses to manage their blood sugar levels effectively.

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